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Information on SUBCLASS 4.49.1
Subclass Accession number: 1346
Subclass: 4.49.1 PSSM
Type: EH beta-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 2.5 (>50 %)  2.5 (>75 %)  2.5.1 (>50 %)  2.5.1 (>75 %)  2.5.1.152.5.1.18
GO : GO:0004156 (>50 %)  GO:0004364 (>75 %)  GO:0016765 (>50 %)  GO:0016765 (>75 %)  
SCOP : 51604 (>75 %)  51609 (>75 %)  51717 (>50 %)  51718 (>50 %)  52832 (>75 %)  52833 (>75 %)  52862 (>75 %)  
 Number of loops: 3

Average sequence ID (%) : 39.7 +/- 13.5
Average RMSD (Å) : 0.400 +/- 0.100

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: YhXVphXX
(φψ)-conformation: bpabaeaa
Pattern: [MY][IT][IL][FGV][Y][FW][NP][V][KR][AG]x[ACT][EH][AP][ILM][R][LMY][L][FL][AE][DY]
Conservation:0.005-0.6190.102-1.8532.8281.014-0.3780.7560.4800.013-1.105-0.7790.118-0.097-0.2421.447-0.7790.756-0.343-0.777-0.546
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1glq_A_31glq   A323YTIVYFPVRGRCEAMRMLLADEEEEE-SSSGGGHHHHHHHHHbbbbbxabaeaaaaaaaaaaa
1m0u_A_501m0u   A5070YTLFYFNVKALAEPLRYLFAYEEEEEESSSGGGHHHHHHHHHbbbbbxabaeaaaaaaaaaaa
2gst_A_22gst   A222MILGYWNVRGLTHPIRLLLEYEEEEEESS-TTTHHHHHHHHHxbbbbxabaeaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1glq_A_31glq   A     GTBS-(P-NITROBENZYL)GLUTATHIONE Y - 7
1glq_A_31glq   A     GTBS-(P-NITROBENZYL)GLUTATHIONE F - 8
1glq_A_31glq   A     GTBS-(P-NITROBENZYL)GLUTATHIONE P - 9
1glq_A_31glq   A     GTBS-(P-NITROBENZYL)GLUTATHIONE V - 10
1glq_A_31glq   A     GTBS-(P-NITROBENZYL)GLUTATHIONE G - 12
1glq_A_31glq   A     GTBS-(P-NITROBENZYL)GLUTATHIONE R - 13
1m0u_A_501m0u   A     GTTGLUTATHIONE Y - 54
1m0u_A_501m0u   A     GTTGLUTATHIONE F - 55
1m0u_A_501m0u   A     GTTGLUTATHIONE A - 59
1m0u_A_501m0u   A     GTTGLUTATHIONE L - 60
2gst_A_22gst   A     GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE Y - 6
2gst_A_22gst   A     GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE W - 7
2gst_A_22gst   A     GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE V - 9
2gst_A_22gst   A     GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE R - 10
2gst_A_22gst   A     GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE G - 11
2gst_A_22gst   A     GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE L - 12

Clusters included in this Subclass
CLUSTER: EH.6.221