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Information on SUBCLASS 5.1.2
Subclass Accession number: 1360
Subclass: 5.1.2 PSSM
Type: EH beta-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.1 (>75 %)  3.1.1 (>75 %)  3.1.1.4
GO : GO:0005509 (>75 %)  GO:0016298 (>75 %)  GO:0016788 (>75 %)  GO:0016789 (>75 %)  
SCOP : 48618 (>75 %)  48619 (>75 %)  48623 (>75 %)  
 Number of loops: 40

Average sequence ID (%) : 10.2 +/- 12.9
Average RMSD (Å) : 0.970 +/- 0.304

Consensus geometry
d (Å): 11 delta (°): 45-90 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: XhpXXXpXp
(φψ)-conformation: bbpaappaa
Pattern: x[acfgikltv]x[ACFGILPTV][acdgnpst]x[adegknrst]x[dehnpqst]x[cdehknqrs][adegknqrt][acfgiklmv]x
Conservation:-1.000-0.079-0.8600.7750.280-1.4010.138-0.6871.550-0.8360.6861.778-0.179-1.164
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a4i_A_661a4i   A6982HIKLPRTTTESEVMEEEE-TT--HHHHHbbbxxaaxbaaaaa
1aky_*_1971aky   -197210WAGVDASQPPATVWEEEEETTS-HHHHHxbbbxaaxxaaaaa
1atz_A_9271atz   A932945LLDGSSSFPASYFDEEE-SSSS-HHHHHxxxaxaabwaaaaa
1bjn_A_3341bjn   A335348RASIYNAMPLEGVKEEE--TTS-HHHHHbbxbxaaxxaaaaa
1bw0_A_3871bw0   A387400FTRLTTTRPVEVYREEEEE--S-HHHHHbbbbxaaxxaaaaa
1d0n_A_5781d0n   A578589..WVGAGASEAEKT..EE-TT--HHHHH..pbxaaxbaaaaa
1dqn_A_1981dqn   A198209..LFDINLSESEVT..EEESSS-HHHHH..xbbaaxxaaaaa
1eg5_A_3471eg5   A350363RISLCKYNTEEEVDEEE--TT--HHHHHbbbxbaaxbaaaaa
1elu_A_3671elu   A369382RACCHYITDEEEINEEE--TT--HHHHHbbbbbaaxbaaaaa
1g4i_A_811g4i   A8194EITCSSENNACEAFEEEE-TTS-HHHHHbxbxxaapxaaaaa
1gkp_A_871gkp   A93106MCCPSRNDDALEGYEE---TTS-HHHHHxxaxxaabxaaaaa
1hn0_A_8711hn0   A874887EYMVFLDATPEKMGEEEEETT--HHHHHbbbbbaaxbaaaaa
1ijb_A_5131ijb   A518531LLDGSSRLSEAEFEEEE-BTTS-HHHHHbbxaxaabxaaaaa
1jf9_A_3771jf9   A379392RASLAMYNTHEEVDEEE--TT--HHHHHbbbbxaaxbaaaaa
1jj2_X_2011jj2   X202215AVRIASKVGARKREEEEE-TTS-HHHHHbbbxpaapxaaaaa
1jms_A_3441jms   A346359FLITSPEATEDEEQEEEE-TT--HHHHHbbbbbaaxxaaaaa
1luc_A_1911luc   A191202..ILSWIINTHEKK..EE-SSS-HHHHH..bxxaabxaaaaa
1luc_B_1901luc   B190202.LVFRWDDSNAQRK.EEE-TTS-HHHHH.bbxxaaxxaaaaa
1m1n_A_3731m1n   A375388VGTGYEFAHNDDYDEEEEESS--HHHHHabbbbaNxbaaaaa
1m2o_A_1231m2o   A125138FFVVDLTSETENLDEEEEE--S-HHHHHbxbbxaabpaaaaa
1m6s_A_3141m6s   A316329RLVTHKDVSRNDIEEEE--TTS-HHHHHbbbxbaabxaaaaa
1mf7_A_1331mf7   A138151LIDGSGSIIPHDFREEE--TTS-HHHHHbbxapaaxxaaaaa
1mjn_A_1301mjn   A135148LFDGSMSLQPDEFQEEE-BTT--HHHHHbbxaxaaxxaaaaa
1n62_C_691n62   C6982DVVIGAMTTQHALIEEEEETT-BHHHHHbbbbxaaxxaaaaa
1nbw_A_1331nbw   A134147IVLIDDAVDFLDAVEEEE-SSS-HHHHHbxxbxaabpaaaaa
1nfp_*_921nfp   -92104.LLFKWDDSQQKRI.EEE-TTS-HHHHH.bbxxaaxxaaaaa
1nij_A_651nij   A6577.ICCSRSNELEDAL.EEE-TTS-HHHHH.bbbxaaxxaaaaa
1nn5_A_1751nn5   A175188WKMVDASKSIEAVHEEEEETTS-HHHHHxbxbxaaxxaaaaa
1o4s_A_3511o4s   A351364FVRLSFATSIERLTEEEEE--S-HHHHHbbbbxaabxaaaaa
1p3w_A_3521p3w   A354367RFSLGRFTTEEEIDEEE--TT--HHHHHbbbxbaaxbaaaaa
1p5z_B_2331p5z   B233246ILTLDVNEDFKDKYEEEEE--S-HHHHHbbxbxaaxxaaaaa
1p6x_A_3011p6x   A303316VFSADLSGTPRQCAEEEEE--S-HHHHHxbbbxaaxxaaaaa
1pvm_A_151pvm   A1526..TVNWNTTVFDAV..EEETT-BHHHHH..bbxaaxxaaaaa
1qf9_A_1691qf9   A169182VKIIPANRDVNEVYEEEEE-SS-HHHHHbbxbwaabxaaaaa
1ry6_A_561ry6   A5668.KVFDDTVDNFTVY.EEE-TT--HHHHH.bbbxaaxxaaaaa
1udv_A_71udv   A720EIVVRKTKNVEDHVEEE--SSS-HHHHHxbxxxaabxaaaaa
1vj0_A_1491vj0   A149162VLKVSEKDDLDVLAEEEE-TTS-HHHHHbbxbbaaxxaaaaa
1zin_*_1921zin   -192205LRNINGEQDMEKVFEEEEE-SS-HHHHHxbxbxaabxaaaaa
2gsa_A_4082gsa   A408420.GFTSLAHTEEDID.EE--TT--HHHHH.bbbbaaxbaaaaa
4tmk_A_1844tmk   A184197IHTIDATQPLEAVMEEEEETTS-HHHHHbxxxxaaxwaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1aky_*_1971aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE A - 202
1aky_*_1971aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE S - 203
1aky_*_1971aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 204
1aky_*_1971aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE P - 205
1aky_*_1971aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE P - 206
1aky_*_1971aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE V - 209
1bjn_A_3341bjn   A     LLP2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE) Y - 339
1bjn_A_3341bjn   A     LLP2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE) N - 340
1eg5_A_3471eg5   A     MSESELENOMETHIONINE L - 353
1eg5_A_3471eg5   A     MSESELENOMETHIONINE C - 354
1eg5_A_3471eg5   A     MSESELENOMETHIONINE K - 355
1eg5_A_3471eg5   A     MSESELENOMETHIONINE T - 358
1eg5_A_3471eg5   A     MSESELENOMETHIONINE E - 360
1eg5_A_3471eg5   A     MSESELENOMETHIONINE E - 361
1eg5_A_3471eg5   A     MSESELENOMETHIONINE Y - 364
1elu_A_3671elu   A     PDA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-PROPIONIC ACID R - 369
1g4i_A_811g4i   A     MPD2-METHYL-2,4-PENTANEDIOL F - 106
1gkp_A_871gkp   A     KCXLYSINE NZ-CARBOXYLIC ACID M - 93
1gkp_A_871gkp   A     ZNZINC ION M - 93
1gkp_A_871gkp   A     KCXLYSINE NZ-CARBOXYLIC ACID C - 94
1gkp_A_871gkp   A     KCXLYSINE NZ-CARBOXYLIC ACID C - 95
1jf9_A_3771jf9   A     PLPPYRIDOXAL-5'-PHOSPHATE R - 379
1jms_A_3441jms   A     MGMAGNESIUM ION V - 344
1jms_A_3441jms   A     MGMAGNESIUM ION D - 345
1m1n_A_3731m1n   A     CACALCIUM ION E - 380
1m1n_A_3731m1n   A     HCA3-HYDROXY-3-CARBOXY-ADIPIC ACID E - 380
1m1n_A_3731m1n   A     CFNFE(7)-MO-S(9)-N CLUSTER E - 380
1m1n_A_3731m1n   A     CACALCIUM ION F - 381
1m1n_A_3731m1n   A     HCA3-HYDROXY-3-CARBOXY-ADIPIC ACID F - 381
1m1n_A_3731m1n   A     CFNFE(7)-MO-S(9)-N CLUSTER F - 381
1m6s_A_3141m6s   A     LLP2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE) H - 320
1mjn_A_1301mjn   A     MGMAGNESIUM ION D - 137
1mjn_A_1301mjn   A     MGMAGNESIUM ION S - 139
1mjn_A_1301mjn   A     MGMAGNESIUM ION M - 140
1mjn_A_1301mjn   A     MGMAGNESIUM ION S - 141
1mjn_A_1301mjn   A     MGMAGNESIUM ION L - 142
1n62_C_691n62   C     FADFLAVIN-ADENINE DINUCLEOTIDE A - 74
1n62_C_691n62   C     FADFLAVIN-ADENINE DINUCLEOTIDE M - 75
1n62_C_691n62   C     FADFLAVIN-ADENINE DINUCLEOTIDE Q - 78
1nn5_A_1751nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER A - 180
1nn5_A_1751nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER S - 181
1nn5_A_1751nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER K - 182
1nn5_A_1751nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER S - 183
1nn5_A_1751nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER I - 184
1nn5_A_1751nn5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER V - 187
1p5z_B_2331p5z   B     ADPADENOSINE-5'-DIPHOSPHATE V - 238
1p5z_B_2331p5z   B     ADPADENOSINE-5'-DIPHOSPHATE N - 239
1p5z_B_2331p5z   B     ADPADENOSINE-5'-DIPHOSPHATE E - 240
1p5z_B_2331p5z   B     ADPADENOSINE-5'-DIPHOSPHATE D - 241
1p5z_B_2331p5z   B     ADPADENOSINE-5'-DIPHOSPHATE F - 242
1p5z_B_2331p5z   B     ADPADENOSINE-5'-DIPHOSPHATE K - 243
1qf9_A_1691qf9   A     ADPADENOSINE-5'-DIPHOSPHATE A - 174
1qf9_A_1691qf9   A     ADPADENOSINE-5'-DIPHOSPHATE N - 175
1qf9_A_1691qf9   A     ADPADENOSINE-5'-DIPHOSPHATE R - 176
1qf9_A_1691qf9   A     ADPADENOSINE-5'-DIPHOSPHATE D - 177
1qf9_A_1691qf9   A     ADPADENOSINE-5'-DIPHOSPHATE V - 178
1qf9_A_1691qf9   A     ADPADENOSINE-5'-DIPHOSPHATE N - 179
1qf9_A_1691qf9   A     ADPADENOSINE-5'-DIPHOSPHATE V - 181
1udv_A_71udv   A     ZNZINC ION K - 14
1udv_A_71udv   A     ZNZINC ION D - 18
1udv_A_71udv   A     ZNZINC ION H - 19
1udv_A_71udv   A     ZNZINC ION D - 22
1zin_*_1921zin   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 197
1zin_*_1921zin   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE E - 198
1zin_*_1921zin   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 199
1zin_*_1921zin   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE D - 200
1zin_*_1921zin   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE M - 201
1zin_*_1921zin   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE V - 204
4tmk_A_1844tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE L - 193

Clusters included in this Subclass
CLUSTER: EH.3.66
CLUSTER: EH.4.21
CLUSTER: EH.4.88
CLUSTER: EH.5.16
CLUSTER: EH.5.9
CLUSTER: EH.6.68
CLUSTER: EH.6.72
CLUSTER: EH.6.77
CLUSTER: EH.6.82
CLUSTER: EH.7.15