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Information on SUBCLASS 5.6.2
Subclass Accession number: 1387
Subclass: 5.6.2 PSSM
Type: EH beta-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 2.6 (>75 %)  2.6.1 (>75 %)  2.6.1.1 (>75 %)  2.7.4 (>75 %)  
GO : GO:0004069 (>75 %)  GO:0005524 (>75 %)  GO:0008168 (>75 %)  GO:0008483 (>75 %)  GO:0008757 (>75 %)  GO:0016301 (>75 %)  GO:0016741 (>75 %)  GO:0016769 (>75 %)  GO:0016772 (>75 %)  GO:0030554 (>75 %)  
SCOP : 52539 (>75 %)  52540 (>75 %)  52541 (>75 %)  53334 (>75 %)  53335 (>75 %)  53382 (>75 %)  53383 (>75 %)  53384 (>75 %)  
 Number of loops: 8

Average sequence ID (%) : 29.4 +/- 22.2
Average RMSD (Å) : 0.463 +/- 0.160

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: phhXhpGhh
(φψ)-conformation: bplaeagaa
Pattern: [HKNRST][FV][AILY][DE][AILPV][AFGY][ACGST][AGS]x[G][AGIPV][AFILM]xx[AGS][afilv][aer]
Conservation:-0.2900.681-0.1211.681-0.372-0.230-0.3250.861-0.8672.720-0.779-0.180-1.083-0.9320.348-0.586-0.525
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1g38_A_421g38   A4258RVLEPACAHGPFLRAFREEEEET-TT-HHHHHHHxbbbxlaeavaaaaaaa
1g55_A_41g55   A521RVLELYSGVGGMHHALREEEEET-TT-HHHHHHHxxxbxlaeavaaaaaaa
1im8_A_581im8   A5874NVYDLGCSRGAATLSAREEEEES-TT-HHHHHHHbbbbxvaeavaaaaaaa
1ne2_A_511ne2   A5167SVIDAGTGNGILACGSYEEEEET-TT-HHHHHHHxbbbxvaeavaaaaaaa
1nv8_A_1241nv8   A124140TVADIGTGSGAIGVSVAEEEEES-TTSHHHHHHHbbbbxvaeagaaaaaaa
1qzz_A_1851qzz   A185201HVLDVGGGNGGMLAAIAEEEEET-TTSHHHHHHHbbxbxvaeavaaaaaaa
1ufk_A_1231ufk   A123139KVLDLGTGSGVLAIAAEEEEEET-TT-HHHHHHHxbbbxvaeavaaaaaaa
6mht_A_136mht   A1329RFIDLFAGLGGFRLALEEEEEET-TT-HHHHHHHbbbbxlaeavaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1g38_A_421g38   A     NEA5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE E - 45
1g38_A_421g38   A     NEA5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE P - 46
1g38_A_421g38   A     NEA5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE A - 47
1g38_A_421g38   A     NEA5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE C - 48
1g38_A_421g38   A     NEA5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE A - 49
1g38_A_421g38   A     NEA5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE P - 52
1g38_A_421g38   A     NEA5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE F - 53
1g55_A_41g55   A     SAHS-ADENOSYL-L-HOMOCYSTEINE E - 8
1g55_A_41g55   A     SAHS-ADENOSYL-L-HOMOCYSTEINE L - 9
1g55_A_41g55   A     SAHS-ADENOSYL-L-HOMOCYSTEINE Y - 10
1g55_A_41g55   A     SAHS-ADENOSYL-L-HOMOCYSTEINE S - 11
1g55_A_41g55   A     SAHS-ADENOSYL-L-HOMOCYSTEINE G - 12
1g55_A_41g55   A     SAHS-ADENOSYL-L-HOMOCYSTEINE V - 13
1g55_A_41g55   A     SAHS-ADENOSYL-L-HOMOCYSTEINE G - 14
1g55_A_41g55   A     SAHS-ADENOSYL-L-HOMOCYSTEINE G - 15
1g55_A_41g55   A     SAHS-ADENOSYL-L-HOMOCYSTEINE M - 16
1im8_A_581im8   A     MSESELENOMETHIONINE N - 58
1im8_A_581im8   A     MSESELENOMETHIONINE V - 59
1im8_A_581im8   A     MSESELENOMETHIONINE Y - 60
1im8_A_581im8   A     MSESELENOMETHIONINE D - 61
1im8_A_581im8   A     SAIS-ADENOSYL-L-HOMOSELENOCYSTEINE D - 61
1im8_A_581im8   A     SAIS-ADENOSYL-L-HOMOSELENOCYSTEINE L - 62
1im8_A_581im8   A     SAIS-ADENOSYL-L-HOMOSELENOCYSTEINE G - 63
1im8_A_581im8   A     MSESELENOMETHIONINE C - 64
1im8_A_581im8   A     SAIS-ADENOSYL-L-HOMOSELENOCYSTEINE C - 64
1im8_A_581im8   A     MSESELENOMETHIONINE S - 65
1im8_A_581im8   A     SAIS-ADENOSYL-L-HOMOSELENOCYSTEINE S - 65
1im8_A_581im8   A     MSESELENOMETHIONINE R - 66
1im8_A_581im8   A     SAIS-ADENOSYL-L-HOMOSELENOCYSTEINE R - 66
1im8_A_581im8   A     SAIS-ADENOSYL-L-HOMOSELENOCYSTEINE G - 67
1im8_A_581im8   A     SAIS-ADENOSYL-L-HOMOSELENOCYSTEINE A - 68
1im8_A_581im8   A     SAIS-ADENOSYL-L-HOMOSELENOCYSTEINE A - 69
1im8_A_581im8   A     SAIS-ADENOSYL-L-HOMOSELENOCYSTEINE T - 70
1im8_A_581im8   A     MSESELENOMETHIONINE S - 72
1im8_A_581im8   A     MSESELENOMETHIONINE A - 73
1ne2_A_511ne2   A     MSESELENOMETHIONINE I - 53
1ne2_A_511ne2   A     MSESELENOMETHIONINE D - 54
1ne2_A_511ne2   A     MSESELENOMETHIONINE A - 55
1ne2_A_511ne2   A     MSESELENOMETHIONINE T - 57
1ne2_A_511ne2   A     MSESELENOMETHIONINE L - 62
1nv8_A_1241nv8   A     SAMS-ADENOSYLMETHIONINE D - 127
1nv8_A_1241nv8   A     SAMS-ADENOSYLMETHIONINE I - 128
1nv8_A_1241nv8   A     SAMS-ADENOSYLMETHIONINE G - 129
1nv8_A_1241nv8   A     SAMS-ADENOSYLMETHIONINE T - 130
1nv8_A_1241nv8   A     SAMS-ADENOSYLMETHIONINE G - 131
1nv8_A_1241nv8   A     SAMS-ADENOSYLMETHIONINE S - 132
1nv8_A_1241nv8   A     SAMS-ADENOSYLMETHIONINE G - 133
1nv8_A_1241nv8   A     SAMS-ADENOSYLMETHIONINE A - 134
1nv8_A_1241nv8   A     SAMS-ADENOSYLMETHIONINE I - 135
1qzz_A_1851qzz   A     ACTACETATE ION D - 188
1qzz_A_1851qzz   A     SAMS-ADENOSYLMETHIONINE D - 188
1qzz_A_1851qzz   A     ACTACETATE ION V - 189
1qzz_A_1851qzz   A     SAMS-ADENOSYLMETHIONINE V - 189
1qzz_A_1851qzz   A     ACTACETATE ION G - 190
1qzz_A_1851qzz   A     SAMS-ADENOSYLMETHIONINE G - 190
1qzz_A_1851qzz   A     ACTACETATE ION G - 191
1qzz_A_1851qzz   A     SAMS-ADENOSYLMETHIONINE G - 191
1qzz_A_1851qzz   A     ACTACETATE ION G - 192
1qzz_A_1851qzz   A     SAMS-ADENOSYLMETHIONINE G - 192
1qzz_A_1851qzz   A     ACTACETATE ION N - 193
1qzz_A_1851qzz   A     SAMS-ADENOSYLMETHIONINE N - 193
1qzz_A_1851qzz   A     ACTACETATE ION G - 194
1qzz_A_1851qzz   A     ACTACETATE ION G - 195
1qzz_A_1851qzz   A     SAMS-ADENOSYLMETHIONINE G - 195
1qzz_A_1851qzz   A     ACTACETATE ION M - 196
1qzz_A_1851qzz   A     SAMS-ADENOSYLMETHIONINE M - 196
1qzz_A_1851qzz   A     ACTACETATE ION L - 197
1qzz_A_1851qzz   A     ACTACETATE ION A - 198
6mht_A_136mht   A     SAMS-ADENOSYLMETHIONINE L - 17
6mht_A_136mht   A     SAMS-ADENOSYLMETHIONINE F - 18
6mht_A_136mht   A     SAMS-ADENOSYLMETHIONINE A - 19
6mht_A_136mht   A     SAMS-ADENOSYLMETHIONINE G - 20
6mht_A_136mht   A     SAMS-ADENOSYLMETHIONINE L - 21
6mht_A_136mht   A     SAMS-ADENOSYLMETHIONINE G - 22
6mht_A_136mht   A     SAMS-ADENOSYLMETHIONINE G - 23
6mht_A_136mht   A     SAMS-ADENOSYLMETHIONINE F - 24

Clusters included in this Subclass
CLUSTER: EH.4.64