Information on SUBCLASS 8.1.1 |
Subclass Accession number: 143
Subclass: 8.1.1 Type: HE alpha-beta DB: ArchDB-KI |
Number of loops: 22 Average sequence ID (%) : 35.1 +/- 4.4 Average RMSD (Å) : 0.85 +/- 0.42 Consensus geometry
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Consensus Sequence: | pXhpHXphhpLX |
(φψ)-conformation: | aapbbaabppba |
Pattern: | {ILMV} | {KLM} | {HKNQS} | x | {AFGILV} | {HKNQRT} | {H} | x | {HKNRT} | [ILV] | [ILV] | {HKNQRS} | [IL] | x | x | x |
Conservation: | 0.474 | 0.262 | -0.566 | -1.406 | -0.873 | -0.381 | 1.747 | -0.379 | -0.244 | 1.163 | 1.349 | -0.534 | 1.664 | -1.015 | -0.945 | -0.317 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1a06_*_65 | 1a06 | - | 69 | 84 | VLHKIKHPNIVALDDI | HHHT---TTB--EEEE | aaaaxbbaabxxbabb |
1ad5_A_304 | 1ad5 | A | 313 | 328 | VMKTLQHDKLVKLHAV | HHTT---TTB--EEEE | aaaaxxbaabxxxabb |
1apm_E_85 | 1apm | E | 94 | 109 | ILQAVNFPFLVKLEFS | HHHH---TTB--EEEE | aaaaxbbaabxxxabb |
1aq1_*_46 | 1aq1 | - | 54 | 69 | LLKELNHPNIVKLLDV | HHTT---TTB--EEEE | aaaaxbbaabpxxabb |
1b38_A_46 | 1b38 | A | 54 | 69 | LLKELNHPNIVKLLDV | HHTT---TTB--EEEE | aaaaxbbaabpxxabb |
1cdk_A_85 | 1cdk | A | 94 | 109 | ILQAVNFPFLVKLEYS | HHHH---TTB--EEEE | aaaaxbbaabxxxabb |
1ckp_*_46 | 1ckp | - | 54 | 69 | LLKELNHPNIVKLLDV | HHTT---TTB--EEEE | aaaaxbbaabpxxabb |
1erk_*_60 | 1erk | - | 72 | 87 | ILLRFRHENIIGINDI | HHHH---TTB--EEEE | aaaaxbbaabpbxabb |
1fgk_A_522 | 1fgk | A | 535 | 550 | MKMIGKHKNIINLLGA | HHHH---TTB--EEEE | aaaaexbaabxxxaeb |
1hcl_*_46 | 1hcl | - | 54 | 69 | LLKELNHPNIVKLLDV | HHTT---TTB--EEEE | aaaaxbbaabxxxabb |
1ir3_A_1038 | 1ir3 | A | 1050 | 1065 | VMKGFTCHHVVRLLGV | HHHT---TTB--EEEE | aaaabbbaabpxxaeb |
1irk_*_1038 | 1irk | - | 1050 | 1065 | VMKGFTCHHVVRLLGV | HHTT---TTB--EEEE | aaaabbbaabpbxaeb |
1jnk_*_102 | 1jnk | - | 114 | 129 | LMKCVNHKNIISLLNV | HHHH---TTB--EEEE | aaaaxbbaabpxxabb |
1jsu_A_46 | 1jsu | A | 54 | 69 | LLKELNHPNIVKLLDV | HHTT---TTB--EEEE | aaaabxbaabpxxabb |
1koa_*_5978 | 1koa | - | 5990 | 6005 | TMSVLRHPTLVNLHDA | HHHHT--TTB--EEEE | aaaaapbaabpxxabb |
1kob_A_89 | 1kob | A | 101 | 116 | IMNQLHHPKLINLHDA | HHTT--STTB--EEEE | aaaaaxbaabpxxabb |
1phk_*_60 | 1phk | - | 77 | 92 | LRKVSGHPNIIQLKDT | HHHHTT-TTB--EEEE | aaaapgxaabxbxabb |
1tki_A_60 | 1tki | A | 71 | 86 | ILNIARHRNILHLHES | HHHHS--TTB--EEEE | aaaaxxbaabpxxabb |
1ydr_E_85 | 1ydr | E | 94 | 109 | ILQAVNFPFLVKLEFS | HHHH---TTB--EEEE | aaaaxbbaabxxxabb |
2ptk_*_313 | 2ptk | - | 313 | 328 | VMKKLRHEKLVQLYAV | HHHH---TTB--EEEE | aaaapbbaabpxxabb |
2src_*_304 | 2src | - | 313 | 328 | VMKKLRHEKLVQLYAV | HHHT---TTB--EEEE | aaaaxbbaabxxxabb |
3lck_*_282 | 3lck | - | 291 | 306 | LMKQLQHQRLVRLYAV | HHHT---TTB--EEEE | aaaabxbaabpxxabF |
PDB ligands within a cut-off distance of 6 Å in this subclass |
Loop | PDB | Chain | Ligands | Residue |
1ad5_A_304 | 1ad5 | A | ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | V - 323 |
1apm_E_85 | 1apm | E | PHOPHEOPHYTIN A | H - 87 |
1apm_E_85 | 1apm | E | PHOPHEOPHYTIN A | N - 90 |
1apm_E_85 | 1apm | E | OCTN-OCTANE | F - 100 |
1aq1_*_46 | 1aq1 | * | STUSTAUROSPORINE | V - 64 |
1b38_A_46 | 1b38 | A | ATPADENOSINE-5'-TRIPHOSPHATE | V - 64 |
1jsu_A_46 | 1jsu | A | TPOPHOSPHOTHREONINE | R - 50 |
1phk_*_60 | 1phk | * | ATPADENOSINE-5'-TRIPHOSPHATE | E - 73 |
1phk_*_60 | 1phk | * | MNMANGANESE (II) ION | E - 73 |
1phk_*_60 | 1phk | * | ATPADENOSINE-5'-TRIPHOSPHATE | I - 87 |
1ydr_E_85 | 1ydr | E | TPOPHOSPHOTHREONINE | H - 87 |
1ydr_E_85 | 1ydr | E | TPOPHOSPHOTHREONINE | N - 90 |
1ydr_E_85 | 1ydr | E | IQP1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE | V - 104 |
Bibliographic annotations |
Clusters included in this Subclass |
CLUSTER: HE.7.0 |
CLUSTER: HE.8.0 |
CLUSTER: HE.9.0 |
CLUSTER: HE.9.1 |
CLUSTER: HE.9.5 |