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Information on SUBCLASS 8.2.1
Subclass Accession number: 144
Subclass: 8.2.1
Type: HE alpha-beta
DB: ArchDB-KI
 Number of loops: 8

Average sequence ID (%) : 26.7 +/- 1.0
Average RMSD (Å) : 0.88 +/- 0.45

Consensus geometry
d (Å): 7 delta (°): 45-90 theta (°): 90-135 rho (°): 135-180
Consensus Sequence: pXhpHXphVphh
(φψ)-conformation: aabbbaabppba
Pattern: {DEKNR}[EL]{AIL}x[ILMV]{CLM}[KRS]{EKLM}{FGILV}[DHKNQT]{HN}x{HNR}[ILV][IV][KNQR][FLMY]{LWY}{AGY}x{CFVY}
Conservation:-0.4610.990-1.137-1.3440.853-0.0550.977-0.901-1.198-0.4211.761-0.6150.2481.2641.8450.5970.389-0.536-0.148-1.145-0.961
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1f3m_D_3121f3m   D314334NEILVMRENKNPNIVNYLDSYHHHHHHTT---TTB--EEEEEaaaaaaaabbbaabxxxabbb
1fot_A_1291fot   A134154DERLMLSIVTHPFIIRMWGTFHHHHHHHS--BTTB--EEEEEaaaaaaaabbbaabpbbaebe
1fvr_B_8681fvr   B872892ELEVLCKLGHHPNIINLLGACHHHHHHT----TTB--EEEEEaaaaaaaaebbaabxxxaebb
1i09_B_961i09   B96116RELQIMRKLDHCNIVRLRYFFHHHHHHTT---TTB--EEEEEaaaaaaaabbbaabxxxabbb
1ia8_A_491ia8   A5474KEICINKMLNHENVVKFYGHRHHHHHHHH---TTB--EEEEEaaaaaaaaxbbaabpxbaebb
1iep_A_2801iep   A285305KEAAVMKEIKHPNLVQLLGVCHHHHHHTT---TTB--EEEEEaaaaaaaabbbaabpxxaebb
1k3a_A_10111k3a   A10191039NEASVMKEFNCHHVVRLLGVVHHHHHHTT---TTB--EEEEEaaaaaaaaxbbaabpxxaebb
1qpc_A_2821qpc   A287307AEANLMKQLQHQRLVRLYAVVHHHHHHHH---TTB--EEEEEaaaaaaaabbbaabpxxabbb
Bibliographic annotations
LoopPDBChainAnnotationResidue
1f3m_D_3121f3m   RefM.LEI,W.LU,W.MENG,M-C.PARRINI,M.J.ECK,B.J.MAYER,S.C.HARRISON. STRUCTURE OF PAK1 IN AN AUTOINHIBITED CONFORMATION REVEALS A MULTISTAGE ACTIVATION SWITCH  CELL (CAMBRIDGE,MASS.) v.102;387,2000DCATALYTIC RESIDUEE - 315

Clusters included in this Subclass
CLUSTER: HE.10.0
CLUSTER: HE.9.3