ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 2.5.4

Subclass Accession number: 155
Subclass: 2.5.4

Type: HE alpha-beta
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.7 (>75 %)
GO : GO:0005507 (>75 %)  GO:0016772 (>50 %)  GO:0046914 (>75 %)
SCOP : 49502 (>75 %)  49503 (>75 %)  49550 (>75 %)

Number of loops: 6

Average sequence ID (%) : 13.9 +/- 14.8
Average RMSD (Å) : 0.717 +/- 0.172

Consensus geometry

d (Å): 7

delta (°): 45-90

theta (°): 90-135

rho (°): 45-90

Consensus Sequence:	pXhXhX
(φψ)-conformation:	aababb

Pattern:	[aegq]	[AEK]	[fgtv]	[acsv]	[EKS]	[fkqr]	[AFV]	[cdps]	[alvy]	x	x
Conservation:	-0.422	1.806	-1.067	-0.175	1.732	-0.471	0.721	-0.699	-0.414	-0.015	-0.994

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1bkc_A_326	1bkc	A	326	336	AEEASKVCLAH	HHHHTTSSEEE	aaaaaababbb
1cnz_A_59	1cnz	A	62	72	VEGCEQADAIL	HHHHHTSSEEE	aaaaaababbx
1gv8_A_151	1gv8	A	153	163	QAVAKFFSASC	HHHHTTSSEEE	aaaaaaxabbb
1io7_A_320	1io7	A	332	342	EEFSKRFRHIE	HHHHTT-SEEE	aaaaaababbb
1o9p_A_312	1o9p	A	330	340	GEVFEGVDVLL	HHHTTT-SEEE	aaaaaababbb
1ovn_A_35	1ovn	A	36	46	EKTVERFPYSV	HHHHTTSSEEE	aaaaaabwbbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1io7_A_320	1io7	A	HEMPROTOPORPHYRIN IX CONTAINING FE	A - 320
1io7_A_320	1io7	A	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 322
1io7_A_320	1io7	A	HEMPROTOPORPHYRIN IX CONTAINING FE	A - 323
1io7_A_320	1io7	A	HEMPROTOPORPHYRIN IX CONTAINING FE	R - 324
1io7_A_320	1io7	A	HEMPROTOPORPHYRIN IX CONTAINING FE	E - 326

Clusters included in this Subclass

CLUSTER: HE.3.156

CLUSTER: HE.4.219

CLUSTER: HE.5.121