Logo
Information on SUBCLASS 12.1.1
Subclass Accession number: 1581
Subclass: 12.1.1 PSSM
Type: EH beta-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 5.3 (>75 %)  5.3 (>75 %)  5.3.1 (>75 %)  5.3.1 (>75 %)  5.3.1.15.3.1.1
GO : GO:0004807 (>75 %)  GO:0004807 (>75 %)  GO:0016853 (>75 %)  GO:0016853 (>75 %)  GO:0016860 (>75 %)  GO:0016860 (>75 %)  GO:0016861 (>75 %)  GO:0016861 (>75 %)  GO:0030151 (>75 %)  GO:0046914 (>75 %)  
SCOP : 51351 (>75 %)  51351 (>75 %)  51352 (>75 %)  51352 (>75 %)  53705 (>75 %)  53706 (>75 %)  53707 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 28.6 +/- 19.9
Average RMSD (Å) : 0.650 +/- 0.129

Consensus geometry
d (Å): 15 delta (°): 45-90 theta (°): 45-90 rho (°): 90-135
Consensus Sequence: hXXKhXDhhhphRXph
(φψ)-conformation: bbppabpppeapbpaa
Pattern: x[ILY]x[ALW]x[EKW][K][AFGV]x[D][AP][LP][GY][EQT][AC][MR][ANPS][DT][CGVY]x[IT][AFL][AV][AEGR][FIL][AY][EHNR]x
Conservation:-0.779-0.036-1.029-0.753-0.849-0.3682.307-1.210-0.3343.0291.1280.5460.3810.0750.6990.524-0.7140.856-1.300-0.9840.143-0.5270.381-0.9390.196-0.039-0.128-0.274
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1eu1_A_4941eu1   A494521AILAMKKVVDPLYEARSDYDIFAALAEREEEEE---S---TT-B-HHHHHHHHHHHbbbxxxpabxpxeaxbxaaaaaaaaaaa
1g8k_A_5461g8k   A546573RIRLSEKFMDPPGTAMADCLIAARIANAEEEEE---S--STT-B-HHHHHHHHHHHxxbbxxxNbxwxeaxbpaaaaaaaaaaa
1kqf_A_6321kqf   A632659WLQWHWKGQDAPGEARNDGEILAGIYHHEEEEE---S--STT-B-HHHHHHHHHHHxxbxbbxabxxxeapbxaaaaaaaaaaa
2nap_A_4772nap   A477504RYSLTEKAVDPPGQCRPTVNTLVEFARREEEEE---S---TT-B-HHHHHHHHHHHxbbxbxxabxxxeaxbxaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1eu1_A_4941eu1   A     GLCGLUCOSE A - 508
1eu1_A_4941eu1   A     GLCGLUCOSE R - 509
1eu1_A_4941eu1   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE D - 511
1eu1_A_4941eu1   A     GLCGLUCOSE D - 513
1eu1_A_4941eu1   A     CDCADMIUM ION R - 521
1g8k_A_5461g8k   A     EDO1,2-ETHANEDIOL R - 546
1g8k_A_5461g8k   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE D - 563
1kqf_A_6321kqf   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE D - 649
2nap_A_4772nap   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE T - 494

Clusters included in this Subclass
CLUSTER: EH.11.6