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Information on SUBCLASS 3.12.1
Subclass Accession number: 1752
Subclass: 3.12.1 PSSM
Type: AR beta-beta link
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 2.7 (>75 %)  2.7.1 (>75 %)  2.7.1.37
SCOP : 48726 (>75 %)  48727 (>75 %)  56111 (>75 %)  56112 (>75 %)  88854 (>75 %)  
 Number of loops: 17

Average sequence ID (%) : 28.9 +/- 25.5
Average RMSD (Å) : 1.035 +/- 0.184

Consensus geometry
d (Å): 11 delta (°): 0-45 theta (°): 45-90 rho (°): 315-360
Consensus Sequence: hhhXGXX
(φψ)-conformation: bbpaebb
Pattern: [fgimvy][aflmvwy][adgq]x[G]xx[agilpv]
Conservation:-0.024-0.3830.187-0.5952.375-0.435-0.584-0.541
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1d7y_A_2301d7y   A232239VVGIGVLAEE-S-EEEbxbaebbp
1dqt_A_1031dqt   A105112GMGNGTQIEE-S-EEEbbxaebxb
1fec_A_2791fec   A281288MLAIGRVPEE-S-EEEbxbaebxp
1fmb_*_481fmb   -4855YQGTGIGGEE---EEEbxbaebbb
1fo0_A_1041fo0   A105112IFGTGTLLEE---EEEbbxaebxb
1fo0_B_1071fo0   B107114YFGEGSRLEE---EEEbxxaebxx
1kq6_A_61kq6   A916IALLGFEKEE---EEEbbxaebbx
1lp9_E_1031lp9   E105112VFGQGTSLEE---EEEbxxaebxb
1m6i_A_3931m6i   A395402VAAVGLEPEE---EEEbbbaebbp
1mju_L_971mju   L97104TFGAGTKLEE---EEEbbxaebxx
1oaq_L_971oaq   L99106VFGGGTKLEE---EEEbxxaebxx
1oga_D_991oga   D100107IFGKGTKLEE---EEExbxaebxb
1oga_E_1041oga   E104111YFGPGTRLEE---EEEbxxaebxb
1pj5_A_841pj5   A8491FNQVGGLEEE---EEEbbxaebbb
1q1r_A_2411q1r   A243250IAGIGLIPEE---EEEbbbaebbx
1viu_A_351viu   A4148VYDRGNGAEEE---EEbbbaexbb
2f5b_H_1212f5b   H121128VWGQGITVEE---EEEbbxaebxb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1fec_A_2791fec   A     FADFLAVIN-ADENINE DINUCLEOTIDE R - 286
1fmb_*_481fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL T - 51
1fmb_*_481fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL G - 52
1fmb_*_481fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL I - 53
1fmb_*_481fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL G - 54
1fmb_*_481fmb   *     HYB[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL G - 55
1kq6_A_61kq6   A     MSESELENOMETHIONINE I - 6
1kq6_A_61kq6   A     GOLGLYCEROL I - 6
1kq6_A_61kq6   A     MSESELENOMETHIONINE R - 7
1kq6_A_61kq6   A     GOLGLYCEROL R - 7
1kq6_A_61kq6   A     MSESELENOMETHIONINE H - 8
1kq6_A_61kq6   A     GOLGLYCEROL H - 8
1kq6_A_61kq6   A     MSESELENOMETHIONINE I - 9
1kq6_A_61kq6   A     MSESELENOMETHIONINE A - 10
1kq6_A_61kq6   A     MSESELENOMETHIONINE L - 11
1kq6_A_61kq6   A     MSESELENOMETHIONINE L - 12
1kq6_A_61kq6   A     MSESELENOMETHIONINE G - 13
1kq6_A_61kq6   A     MSESELENOMETHIONINE F - 14
1kq6_A_61kq6   A     MSESELENOMETHIONINE E - 15
1viu_A_351viu   A     MSESELENOMETHIONINE Y - 53
1viu_A_351viu   A     MSESELENOMETHIONINE N - 54

Clusters included in this Subclass
CLUSTER: AR.4.15