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Information on SUBCLASS 4.4.1
Subclass Accession number: 1797
Subclass: 4.4.1 PSSM
Type: AR beta-beta link
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 2.6 (>75 %)  2.6.1 (>75 %)  2.6.1.1 (>75 %)  
GO : GO:0004069 (>50 %)  GO:0008483 (>75 %)  GO:0016769 (>75 %)  
SCOP : 53382 (>75 %)  53383 (>75 %)  53384 (>75 %)  
 Number of loops: 22

Average sequence ID (%) : 14.9 +/- 16.0
Average RMSD (Å) : 0.618 +/- 0.171

Consensus geometry
d (Å): 9 delta (°): 45-90 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: XhXXGpXh
(φψ)-conformation: bbppgpbb
Pattern: [acfgilvwy]x[ACFILMV]xx[GNS][adegqst]x[fhivy]x
Conservation:-0.624-0.8490.873-0.486-0.3852.252-0.144-0.7910.155-1.000
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1bn8_A_3101bn8   A310319WGIGKSSKIYEEE-TT-EEExbxxplxaxb
1cx4_A_3361cx4   A340348ARCLRGQYF.EEE-TT-EE.bbbbpvxbb.
1e0t_A_831e0t   A8392VSLKAGQTFTEEE-TT-EEExbxxpUxxbb
1ep0_A_1111ep0   A112121FFIPEGFAHGEEE-TTEEEEbxbxpgbxbb
1fi2_A_1281fi2   A129138FVIPRGLMHFEEE-TT--EEbbbppvxxbb
1h5z_A_3371h5z   A337346HRIHEGDLVAEEE-TT-EEEbxbbpgxxbb
1i5p_A_5881i5p   A595604IVASDNTNVTEEE-TTSEEEbbxpxlbxxx
1i5z_A_581i5z   A6270SYLNQGDFI.EEE-TT-EE.bbbbpvxxb.
1izo_A_3061izo   A306315CEFKKGTSVLEEE-TT-EEEbbxbpvxxbb
1l2t_A_161l2t   A2635LNIKEGEFVSEEE-TT-EEEbbbxxvxbbb
1lrh_A_971lrh   A98107FSIPVNDPHQEEE-TT--EEbbxppvxxbb
1n40_A_2971n40   A297306VLVRKGELVLEEE-TT-EEEbxxxpvxxbb
1ne6_A_1871ne6   A190198TSVGEGGSF.EEE-TT-EE.bbbxpgxbb.
1ne6_A_3101ne6   A314322GRLGPSDYF.EEE-TT-EE.bbbbpvxbb.
1o75_A_3821o75   A388397ADFTPGTEYTEEE-TT-EEExbxxpgxxbb
1o7f_A_1021o7f   A105113CTLGIGTAF.EEE-TT-EE.bbbbpvxbb.
1oxx_K_181oxx   K2635INIENGERFGEEE-TT-EEEbbxxpvxbbb
1pk6_A_1771pk6   A185194LQLQQGDQVWEEE-TT-EEEbxbbpvxbbb
1pk6_C_1731pk6   C181190LRLQVGEEVWEEE-TT-EEEbxbbpvxbbb
1pkl_A_981pkl   A99108AVMERGATCYEEE-TT-EEEbxxbpgpxbb
1qwr_A_1641qwr   A165174YYVPSGTLHAEEE-TT--EEbxbppvxxbb
1vj2_A_831vj2   A8493IFVEPNEIHGEEE-TT--EEbbbxpvxxbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1cx4_A_3361cx4   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE I - 339
1cx4_A_3361cx4   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE A - 340
1cx4_A_3361cx4   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE Y - 347
1cx4_A_3361cx4   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE F - 348
1fi2_A_1281fi2   A     MNMANGANESE (II) ION I - 131
1fi2_A_1281fi2   A     MNMANGANESE (II) ION H - 137
1fi2_A_1281fi2   A     MNMANGANESE (II) ION Q - 139
1i5z_A_581i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE E - 58
1i5z_A_581i5z   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL M - 59
1i5z_A_581i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE M - 59
1i5z_A_581i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE L - 61
1i5z_A_581i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE S - 62
1i5z_A_581i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE L - 64
1i5z_A_581i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE F - 69
1i5z_A_581i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE I - 70
1l2t_A_161l2t   A     ATPADENOSINE-5'-TRIPHOSPHATE I - 18
1l2t_A_161l2t   A     ATPADENOSINE-5'-TRIPHOSPHATE Y - 19
1l2t_A_161l2t   A     ATPADENOSINE-5'-TRIPHOSPHATE A - 20
1lrh_A_971lrh   A     ZNZINC ION I - 100
1lrh_A_971lrh   A     ZNZINC ION H - 106
1lrh_A_971lrh   A     NLANAPHTHALEN-1-YL-ACETIC ACID H - 106
1lrh_A_971lrh   A     NLANAPHTHALEN-1-YL-ACETIC ACID V - 108
1ne6_A_1871ne6   A     SP16-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL A - 189
1ne6_A_1871ne6   A     SP16-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL T - 190
1ne6_A_1871ne6   A     SP16-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL V - 192
1ne6_A_1871ne6   A     SP16-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL S - 197
1ne6_A_1871ne6   A     SP16-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL F - 198
1ne6_A_3101ne6   A     SP16-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL V - 313
1ne6_A_3101ne6   A     SP16-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL G - 314
1ne6_A_3101ne6   A     SP16-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL L - 316
1ne6_A_3101ne6   A     SP16-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL Y - 321
1ne6_A_3101ne6   A     SP16-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL F - 322
1oxx_K_181oxx   K     IODIODIDE ION V - 18
1oxx_K_181oxx   K     IODIODIDE ION A - 20
1oxx_K_181oxx   K     IODIODIDE ION D - 22
1oxx_K_181oxx   K     IODIODIDE ION N - 23
1oxx_K_181oxx   K     IODIODIDE ION V - 24
1oxx_K_181oxx   K     IODIODIDE ION N - 25
1oxx_K_181oxx   K     IODIODIDE ION I - 26
1pk6_C_1731pk6   C     CACALCIUM ION Q - 173
1pk6_A_1771pk6   A     CACALCIUM ION Q - 177
1pk6_A_1771pk6   A     CACALCIUM ION V - 178
1qwr_A_1641qwr   A     ZNZINC ION V - 167
1qwr_A_1641qwr   A     ZNZINC ION H - 173
1vj2_A_831vj2   A     MNMANGANESE (II) ION H - 92
1vj2_A_831vj2   A     MNMANGANESE (II) ION F - 94

Clusters included in this Subclass
CLUSTER: AR.3.28
CLUSTER: AR.4.14
CLUSTER: AR.5.11