ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 9.3.1

Subclass Accession number: 191
Subclass: 9.3.1
Type: HH alpha-alpha
DB: ArchDB-KI

Number of loops: 5

Average sequence ID (%) : 58.5 +/- 7.4
Average RMSD (Å) : 0.61 +/- 0.31

Consensus geometry

d (Å): 23

delta (°): 90-135

theta (°): 90-135

rho (°): 315-360

Consensus Sequence:	hhGYPPFhAppXh
(φψ)-conformation:	aagbpabbbabaa

Pattern:	[TV]	[D]	[CMW]	[W]	x	[IL]	[G]	[TV]	[IL]	[AIV]	[Y]	x	[LM]	[AL]	x	[G]	[IY]	x	[P]	[F]	[FLY]	x	[DE]	[NQT]	x	x	[KQ]	[IL]	[FIY]	[E]	[KNQ]	[I]	[LMV]
Conservation:	-0.507	1.168	-0.673	3.408	-0.361	-0.152	1.168	-0.507	-0.152	-0.723	1.616	-1.071	-0.085	-0.783	-0.673	1.168	-0.266	-0.348	1.616	1.168	-0.474	-0.867	0.152	-0.823	-0.773	-1.370	-0.128	-0.152	-0.474	0.720	-0.623	0.272	-0.474

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a06_*_198	1a06	-	199	231	VDCWSIGVIAYILLCGYPPFYDENDAKLFEQIL	HHHHHHHHHHHHHHHSS-S---SSHHHHHHHHH	aaaaaaaaaaaaaaNvbxabbbabaaaaaaaaa
1apm_E_218	1apm	E	219	251	VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV	HHHHHHHHHHHHHHHSS-SS--SSHHHHHHHHH	aaaaaaaaaaaaaaavbxabbbabaaaaaaaaa
1cdk_A_219	1cdk	A	219	251	VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV	HHHHHHHHHHHHHHHSS-SS--SSHHHHHHHHH	aaaaaaaaaaaaaaavbxabbbabaaaaaaaaa
1tki_A_199	1tki	A	201	233	TDMWSLGTLVYVLLSGINPFLAETNQQIIENIM	HHHHHHHHHHHHHHHSS-TT--SSHHHHHHHHH	aaaaaaaaaaaaaaavbxaapbabaaaaaaaaa
1ydr_E_218	1ydr	E	219	251	VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV	HHHHHHHHHHHHHHHSS-SS--SSHHHHHHHHH	aaaaaaaaaaaaaaagbxabbbabaaaaaaaaa

Bibliographic annotations

Loop	PDB	Chain	Annotation	Residue
1cdk_A_219	1cdk RefD.BOSSEMEYER,R.A.ENGH,V.KINZEL,H.PONSTINGL,R.HUBER. PHOSPHOTRANSFERASE AND SUBSTRATE BINDING MECHANISM OF THE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT FROM PORCINE HEART AS DEDUCED FROM THE 2.0 ANGSTROMS STRUCTURE OF THE COMPLEX WITH MN==2+== ADENYLYL IMIDODIPHOSPHATE AND INHIBITOR PEPTIDE PKI(5-24) EMBO J. v.12;849,1993	A	PKI PEPTIDE BINDING RESIDUE	E - 230

Clusters included in this Subclass