ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 6.2.2

Subclass Accession number: 1931
Subclass: 6.2.2

Type: AR beta-beta link
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 3.4 (>75 %)  3.4.23 (>75 %)
GO : GO:0004175 (>75 %)  GO:0004190 (>75 %)  GO:0008233 (>75 %)  GO:0030151 (>75 %)
SCOP : 50629 (>75 %)  50630 (>75 %)  50646 (>75 %)  50684 (>75 %)  50692 (>75 %)  50696 (>75 %)

Number of loops: 4

Average sequence ID (%) : 41.2 +/- 25.8
Average RMSD (Å) : 0.400 +/- 0.141

Consensus geometry

d (Å): 11

delta (°): 90-135

theta (°): 135-180

rho (°): 0-45

Consensus Sequence:	hDTGXpXXhh
(φψ)-conformation:	pbaababpbb

Pattern:	[KQY]	[DKP]	[FI]	[KNTY]	[FLV]	[il]	[FL]	[D]	[T]	[G]	[AS]	[DS]	x	[LT]	[IW]	[ILV]	[ANP]
Conservation:	-0.590	-0.713	0.210	-1.150	-0.539	-1.098	0.210	1.998	1.419	1.998	0.027	-0.082	-0.958	-0.419	0.532	0.077	-0.921

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1mpp_*_25	1mpp	-	25	41	QDFYLLFDTGSSDTWVP	EEEEEEEETT----EEE	bxbbbxxbaabaxxbbx
1qdm_A_29	1qdm	A	29	45	QKFTVIFDTGSSNLWVP	EEEEEEEETT----EEE	xxbxbbxxaababbbbx
2apr_*_28	2apr	-	28	44	KKFNLDFDTGSSDLWIA	EEEEEEEETT----EEE	bxbxbxxbaababbbbx
4fiv_*_23	4fiv	-	23	39	YPIKFLLDTGADITILN	EEEEEEE-TT-SS-EEE	bwbxxxxbaababxbbx

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
2apr_*_28	2apr	*	CACALCIUM ION	D - 33
2apr_*_28	2apr	*	CACALCIUM ION	D - 35
4fiv_*_23	4fiv	*	1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE	L - 28
4fiv_*_23	4fiv	*	1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE	D - 30
4fiv_*_23	4fiv	*	1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE	T - 31
4fiv_*_23	4fiv	*	1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE	G - 32
4fiv_*_23	4fiv	*	1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE	A - 33
4fiv_*_23	4fiv	*	1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE	D - 34
4fiv_*_23	4fiv	*	1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE	I - 35
4fiv_*_23	4fiv	*	1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE	T - 36
4fiv_*_23	4fiv	*	1NI4-[2-(2-ACETYLAMINO-3-NAPHTHALEN-1-YL-PROPIONYLAMINO)-3-METHYL-BUTYRYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL) -PROPYL]-AMIDE	I - 37

Clusters included in this Subclass

CLUSTER: AR.7.31