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Information on SUBCLASS 8.12.1
Subclass Accession number: 1995
Subclass: 8.12.1 PSSM
Type: AR beta-beta link
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 2.1 (>50 %)  2.1.1 (>50 %)  
GO : GO:0005489 (>75 %)  GO:0005507 (>75 %)  GO:0005529 (>75 %)  GO:0008168 (>50 %)  GO:0008757 (>50 %)  GO:0016741 (>50 %)  GO:0030246 (>75 %)  
SCOP : 49502 (>75 %)  49503 (>75 %)  49504 (>75 %)  50352 (>75 %)  50370 (>75 %)  50371 (>75 %)  51268 (>50 %)  82199 (>50 %)  
 Number of loops: 3

Average sequence ID (%) : 28.9 +/- 19.2
Average RMSD (Å) : 0.333 +/- 0.058

Consensus geometry
d (Å): 15 delta (°): 90-135 theta (°): 90-135 rho (°): 90-135
Consensus Sequence: hXpXXcXppQpW
(φψ)-conformation: bbppalpaaabb
Pattern: [IV]x[LV][KWY][QT][CDW]x[DN][GS][DS][NR][Q][KRY][W][ITY]
Conservation:0.262-0.899-0.102-0.379-0.269-0.769-0.7260.3040.007-0.1770.0640.833-0.5523.172-0.769
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1knm_A_1141knm   A114128IQLYTCSNGSNQRWTEEEE-----GGG-EEbbxbpxavxaaabbb
1qxm_A_1731qxm   A173187IVLWQWFDSSRQKWIEEEE-----GGG-EExbxbxxalxaaabbx
1qxm_A_801qxm   A8094VSVKTDTNGDNQYWYEEEE-----GGG-EEbbbbpxavxaaabbx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1knm_A_1141knm   A     LATLACTOSE Q - 115
1knm_A_1141knm   A     LATLACTOSE Y - 117
1knm_A_1141knm   A     LATLACTOSE T - 118
1knm_A_1141knm   A     LATLACTOSE S - 120
1knm_A_1141knm   A     GOLGLYCEROL N - 121
1knm_A_1141knm   A     LATLACTOSE N - 124
1knm_A_1141knm   A     LATLACTOSE Q - 125
1knm_A_1141knm   A     GOLGLYCEROL R - 126
1qxm_A_801qxm   A     EDO1,2-ETHANEDIOL D - 85
1qxm_A_801qxm   A     EDO1,2-ETHANEDIOL Y - 94
1qxm_A_801qxm   A     EDO1,2-ETHANEDIOL L - 95
1qxm_A_801qxm   A     EDO1,2-ETHANEDIOL L - 96
1qxm_A_801qxm   A     EDO1,2-ETHANEDIOL Q - 97

Clusters included in this Subclass
CLUSTER: AR.8.26