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Information on SUBCLASS 1.1.1
Subclass Accession number: 2025
Subclass: 1.1.1 PSSM
Type: HH alpha-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 80

Average sequence ID (%) : 10.8 +/- 14.0
Average RMSD (Å) : 0.491 +/- 0.193

Consensus geometry
d (Å): 7 delta (°): 0-45 theta (°): 45-90 rho (°): 180-225
Consensus Sequence: XXpXX
(φψ)-conformation: aapaa
Pattern: [adegknqrst][acfilmvwy]x[adegknqrst][adegknqrst][adegnpst]xxx
Conservation:-0.8030.174-0.9790.1561.3521.754-0.867-0.8280.041
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a6m_*_521a6m   -5462EMKASEDLKHHHT-HHHHaaaaxaaaa
1amf_*_2071amf   -214222DYLKGPQAAHHHTSHHHHaaaaxaaaa
1atg_*_2041atg   -212220SWMKGPKAVHHTTSHHHHaaaaxaaaa
1aw9_*_1891aw9   -197205AIVARPAFQHHHHSHHHHaaaapaaaa
1bed_*_1171bed   -122130AAYNGFAVDHHHTSHHHHaaaaxaaaa
1bpy_A_831bpy   A8795KIRQDDTSSHHHH-HHHHaaaaxaaaa
1bs0_A_2701bs0   A281289AVIRSDEGDHHHHSHHHHaaaaxaaaa
1cip_A_1211cip   A129137RLWKDSGVQHHHH-HHHHaaaaxaaaa
1dbh_A_3891dbh   A389397KICSKSLAKHHHHSHHHHaaaapaaaa
1ddz_A_2471ddz   A265273NVCATSIVQHHHHSHHHHaaaaxaaaa
1dv1_A_4181dv1   A423431RIMNDENFQHHHH-HHHHaaaaxaaaa
1dvo_A_1171dvo   A126134AITRSESYLHHHTSHHHHaaaaxaaaa
1eb6_A_1561eb6   A158166DALNNADSYHHHTBHHHHaaaabaaaa
1eem_A_1971eem   A205213AMKEDPTVSHHHT-HHHHaaaaxaaaa
1ef8_A_2241ef8   A236244AVYDSEDYQHHHTSHHHHaaaaxaaaa
1ekm_A_1241ekm   A127135VIRNDPAVIHHHT-HHHHaaaaxaaaa
1elj_A_2771elj   A286294WLTTSEESIHHHH-HHHHaaaaxaaaa
1eu8_A_3061eu8   A314322KFVESYSVQHHHTSHHHHaaaaxaaaa
1exb_A_2711exb   A275283DKILSEEGRHHHHSHHHHaaaaxaaaa
1ezv_H_771ezv   H8492HFKNTEEGKHHHTSHHHHaaaaxaaaa
1f0l_A_1141f0l   A116124EQVGTEEFIHHHTSHHHHaaaaxaaaa
1f0l_A_2061f0l   A219227SLKEHGPIKHHHT-HHHHaaaaxaaaa
1fhj_B_511fhj   B5361AVMSNAKVKHHHH-HHHHaaaaxaaaa
1fio_A_1571fio   A161169EAAISDVGGHHHTSHHHHaaaaxaaaa
1fqi_A_4011fqi   A403411RYLKSPIYKHHHTSHHHHaaaaxaaaa
1fvk_A_1191fvk   A124132AAWNSFVVKHHHH-HHHHaaaaxaaaa
1g4i_A_401g4i   A5462QAKKLDSCKHHHH-HHHHaaaaxaaaa
1g6h_A_2381g6h   A243251NVLSDPKVVHHHH-HHHHaaaapaaaa
1gde_A_2681gde   A276284KALKDERSWHHHT-HHHHaaaaxaaaa
1giq_A_611giq   A6371QIESNPREKHHHT-HHHHaaaaxaaaa
1glq_A_1871glq   A191199AFLSSPEHVHHHTSHHHHaaaaxaaaa
1gpu_A_1571gpu   A158166GCLQEGISSHHHHSHHHHaaaaxaaaa
1gux_A_4731gux   A475483KLLNDNIFHHHHH-HHHHaaaaxaaaa
1gwc_A_1901gwc   A198206RFIELDAAKHHHHSHHHHaaaapaaaa
1hwl_A_5991hwl   A607615AWLETSEGFHHHTSHHHHaaaaxaaaa
1hzt_A_1601hzt   A164172MQATNREARHHHHSHHHHaaaaxaaaa
1i6p_A_1421i6p   A157165NLGHSTIMQHHHHSHHHHaaaaxaaaa
1i7q_A_3421i7q   A351359EMRTDHKELHHHH-HHHHaaaaxaaaa
1itz_A_1681itz   A169177GCQMEGIANHHHHSHHHHaaaaxaaaa
1iuj_A_591iuj   A6472AWTESPAFKHHHTSHHHHaaaaxaaaa
1ivy_A_3071ivy   A311319TYLNNPYVRHHHTSHHHHaaaaxaaaa
1jd5_A_2991jd5   A304312TVAAKPVLAHHHHSHHHHaaaaxaaaa
1jwq_A_1491jwq   A153161ATLFDEDFQHHHT-HHHHaaaaxaaaa
1kek_A_11241kek   A11271135FLMAQNRFAHHHTBHHHHaaaabaaaa
1kgn_A_1251kgn   A134142WSEENENLQHHHH-HHHHaaaaxaaaa
1kiy_A_291kiy   A4553HHFAQPRQQHHHTSHHHHaaaaxaaaa
1kl1_A_2601kl1   A271279GEALQDDFKHHHHSHHHHaaaaxaaaa
1ku0_A_2401ku0   A241249RYDLSVPGAHHHHSHHHHaaaaxaaaa
1l0l_H_161l0l   H2331QCEQLEKCVHHHTSHHHHaaaaxaaaa
1lc0_A_181lc0   A2533RDLKDPRSAHHHTSHHHHaaaaxaaaa
1llf_A_731llf   A8088LVMQSKVFQHHHHSHHHHaaaaxaaaa
1m0u_A_2221m0u   A230238AVNALEPIKHHHTSHHHHaaaaxaaaa
1mvl_A_1431mvl   A144152LMWNNPFTEHHHHSHHHHaaaaxaaaa
1mwq_A_681mwq   A7482WAAQDPYVEHHHT-HHHHaaaapaaaa
1n2a_A_1761n2a   A184192RMAERPEVQHHHTSHHHHaaaaxaaaa
1n45_A_221n45   A2735QAENAEFMRHHHHSHHHHaaaaxaaaa
1n62_C_781n62   C8088ALIGSDFLAHHHH-HHHHaaaaxaaaa
1nd6_A_1301nd6   A138146ETLKSEEFQHHHH-HHHHaaaaxaaaa
1oac_A_1891oac   A198206IINNSEEFAHHHT-HHHHaaaabaaaa
1okt_A_1841okt   A192200FISNLPNIKHHHTSHHHHaaaaxaaaa
1omw_A_1601omw   A164172KFIESDKFTHHHTSHHHHaaaabaaaa
1p80_A_6731p80   A674682DIADNGDANHHHT-HHHHaaaaxaaaa
1p99_A_2501p99   A257265ELYHSKEAQHHHHSHHHHaaaaxaaaa
1pot_*_2681pot   -276284NFLLRPDVAHHHHSHHHHaaaaxaaaa
1puo_A_1431puo   A155163KIYTSPLCLHHHTSHHHHaaaaxaaaa
1q35_A_2431q35   A251259EYLSGEKAQHHHHSHHHHaaaaxaaaa
1q4r_A_741q4r   A7987EYIAHPAHVHHHHSHHHHaaaaxaaaa
1q52_A_2701q52   A285293LAYMTDEAVHHTSHHHHHaaaaxaaaa
1qdl_A_2501qdl   A259267ELMNSEKDKHHHT-HHHHaaaaxaaaa
1qgr_A_2061qgr   A207215ANFDKESERHHHTSHHHHaaaaxaaaa
1qvb_A_311qvb   A3442VWVHDPENTHHHH-HHHHaaaaxaaaa
1r6f_A_2041r6f   A206214IFKASAEYKHHHTSHHHHaaaaxaaaa
1rc7_A_641rc7   A7280AYLISEEFFHHHTSHHHHaaaaxaaaa
1rql_A_531rql   A5967ALTEMPRIAHHHT-HHHHaaaaxaaaa
1s29_A_81s29   A1927EFYFSDVNVHHHTSHHHHaaaaxaaaa
1tfe_*_811tfe   -8290FVARNELFQHHHHSHHHHaaaaxaaaa
1ufa_A_611ufa   A6573EQLADARIKHHHT-HHHHaaaaxaaaa
1usp_A_1161usp   A117125AHEVCPYSAHHHH-HHHHaaaapaaaa
2gsq_*_1752gsq   -183191RVAECPKIAHHHTSHHHHaaaaxaaaa
3thi_A_2833thi   A291299NVMASADTVHHHHSHHHHaaaaxaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a6m_*_521a6m   *     HEMPROTOPORPHYRIN IX CONTAINING FE H - 64
1a6m_*_521a6m   *     OXYOXYGEN MOLECULE H - 64
1a6m_*_521a6m   *     HEMPROTOPORPHYRIN IX CONTAINING FE T - 67
1a6m_*_521a6m   *     HEMPROTOPORPHYRIN IX CONTAINING FE V - 68
1a6m_*_521a6m   *     OXYOXYGEN MOLECULE V - 68
1a6m_*_521a6m   *     HEMPROTOPORPHYRIN IX CONTAINING FE L - 69
1a6m_*_521a6m   *     HEMPROTOPORPHYRIN IX CONTAINING FE A - 71
1a6m_*_521a6m   *     HEMPROTOPORPHYRIN IX CONTAINING FE L - 72
1a6m_*_521a6m   *     HEMPROTOPORPHYRIN IX CONTAINING FE I - 75
1atg_*_2041atg   *     EDO1,2-ETHANEDIOL I - 222
1atg_*_2041atg   *     EDO1,2-ETHANEDIOL A - 225
1aw9_*_1891aw9   *     CDCADMIUM ION H - 190
1dbh_A_3891dbh   A     MSESELENOMETHIONINE K - 389
1dbh_A_3891dbh   A     MSESELENOMETHIONINE I - 390
1dbh_A_3891dbh   A     MSESELENOMETHIONINE C - 391
1dbh_A_3891dbh   A     MSESELENOMETHIONINE S - 392
1eb6_A_1561eb6   A     ZNZINC ION A - 163
1eb6_A_1561eb6   A     ZNZINC ION D - 164
1eb6_A_1561eb6   A     EDO1,2-ETHANEDIOL D - 164
1eb6_A_1561eb6   A     EDO1,2-ETHANEDIOL A - 167
1eb6_A_1561eb6   A     EDO1,2-ETHANEDIOL L - 168
1eb6_A_1561eb6   A     EDO1,2-ETHANEDIOL A - 170
1eb6_A_1561eb6   A     EDO1,2-ETHANEDIOL N - 171
1eb6_A_1561eb6   A     EDO1,2-ETHANEDIOL A - 172
1eb6_A_1561eb6   A     EDO1,2-ETHANEDIOL E - 174
1eb6_A_1561eb6   A     EDO1,2-ETHANEDIOL L - 175
1elj_A_2771elj   A     CMES,S-(2-HYDROXYETHYL)THIOCYSTEINE D - 278
1elj_A_2771elj   A     CMES,S-(2-HYDROXYETHYL)THIOCYSTEINE A - 279
1elj_A_2771elj   A     CMES,S-(2-HYDROXYETHYL)THIOCYSTEINE K - 282
1elj_A_2771elj   A     CMES,S-(2-HYDROXYETHYL)THIOCYSTEINE F - 283
1eu8_A_3061eu8   A     PTPLATINUM (II) ION K - 323
1eu8_A_3061eu8   A     PTPLATINUM (II) ION M - 327
1eu8_A_3061eu8   A     PTPLATINUM (II) ION N - 328
1fhj_B_511fhj   B     HEMPROTOPORPHYRIN IX CONTAINING FE H - 63
1fhj_B_511fhj   B     HEMPROTOPORPHYRIN IX CONTAINING FE K - 66
1fhj_B_511fhj   B     HEMPROTOPORPHYRIN IX CONTAINING FE V - 67
1fhj_B_511fhj   B     HEMPROTOPORPHYRIN IX CONTAINING FE S - 70
1fhj_B_511fhj   B     HEMPROTOPORPHYRIN IX CONTAINING FE F - 71
1fqi_A_4011fqi   A     MSESELENOMETHIONINE Y - 401
1fqi_A_4011fqi   A     MSESELENOMETHIONINE A - 402
1fqi_A_4011fqi   A     MSESELENOMETHIONINE Y - 404
1fqi_A_4011fqi   A     MSESELENOMETHIONINE P - 408
1fqi_A_4011fqi   A     MSESELENOMETHIONINE I - 409
1fqi_A_4011fqi   A     MSESELENOMETHIONINE Y - 410
1fqi_A_4011fqi   A     MSESELENOMETHIONINE K - 411
1g4i_A_401g4i   A     CACALCIUM ION C - 45
1g4i_A_401g4i   A     MPD2-METHYL-2,4-PENTANEDIOL C - 45
1g4i_A_401g4i   A     MPD2-METHYL-2,4-PENTANEDIOL H - 48
1g4i_A_401g4i   A     CACALCIUM ION D - 49
1g4i_A_401g4i   A     MPD2-METHYL-2,4-PENTANEDIOL D - 49
1g4i_A_401g4i   A     MPD2-METHYL-2,4-PENTANEDIOL Y - 52
1gpu_A_1571gpu   A     CACALCIUM ION D - 157
1gpu_A_1571gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE D - 157
1gpu_A_1571gpu   A     CACALCIUM ION G - 158
1gpu_A_1571gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE G - 158
1gpu_A_1571gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE C - 159
1gpu_A_1571gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE E - 162
1i7q_A_3421i7q   A     MGMAGNESIUM ION K - 357
1i7q_A_3421i7q   A     MGMAGNESIUM ION E - 358
1i7q_A_3421i7q   A     BEZBENZOIC ACID E - 358
1i7q_A_3421i7q   A     MGMAGNESIUM ION E - 361
1i7q_A_3421i7q   A     BEZBENZOIC ACID E - 361
1itz_A_1681itz   A     MGMAGNESIUM ION D - 168
1itz_A_1681itz   A     TPPTHIAMINE DIPHOSPHATE D - 168
1itz_A_1681itz   A     MGMAGNESIUM ION G - 169
1itz_A_1681itz   A     TPPTHIAMINE DIPHOSPHATE G - 169
1itz_A_1681itz   A     TPPTHIAMINE DIPHOSPHATE C - 170
1itz_A_1681itz   A     TPPTHIAMINE DIPHOSPHATE M - 172
1itz_A_1681itz   A     TPPTHIAMINE DIPHOSPHATE E - 173
1iuj_A_591iuj   A     ZNZINC ION W - 65
1iuj_A_591iuj   A     ZNZINC ION F - 71
1ivy_A_3071ivy   A     NAGN-ACETYL-D-GLUCOSAMINE T - 307
1ivy_A_3071ivy   A     NAGN-ACETYL-D-GLUCOSAMINE A - 308
1kiy_A_291kiy   A     EDO1,2-ETHANEDIOL L - 55
1lc0_A_181lc0   A     PO4PHOSPHATE ION R - 18
1lc0_A_181lc0   A     PO4PHOSPHATE ION A - 19
1mvl_A_1431mvl   A     FMNFLAVIN MONONUCLEOTIDE M - 145
1mwq_A_681mwq   A     MSESELENOMETHIONINE L - 68
1mwq_A_681mwq   A     ZNZINC ION Y - 80
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE H - 25
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE A - 28
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE E - 29
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE N - 30
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE M - 34
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE R - 35
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE Q - 38
1n62_C_781n62   C     FADFLAVIN-ADENINE DINUCLEOTIDE Q - 78
1puo_A_1431puo   A     MPD2-METHYL-2,4-PENTANEDIOL L - 153
1puo_A_1431puo   A     MPD2-METHYL-2,4-PENTANEDIOL I - 156
1q4r_A_741q4r   A     MSESELENOMETHIONINE A - 76
1q4r_A_741q4r   A     MSESELENOMETHIONINE Y - 80
1s29_A_81s29   A     MSESELENOMETHIONINE F - 22
1s29_A_81s29   A     MSESELENOMETHIONINE V - 27
1ufa_A_611ufa   A     MSESELENOMETHIONINE L - 67
1ufa_A_611ufa   A     MSESELENOMETHIONINE R - 71
1ufa_A_611ufa   A     MSESELENOMETHIONINE I - 72
1ufa_A_611ufa   A     MSESELENOMETHIONINE G - 75
1ufa_A_611ufa   A     MSESELENOMETHIONINE F - 76
1ufa_A_611ufa   A     MSESELENOMETHIONINE Y - 79
1usp_A_1161usp   A     MSESELENOMETHIONINE A - 116
1usp_A_1161usp   A     MSESELENOMETHIONINE A - 117
1usp_A_1161usp   A     MSESELENOMETHIONINE H - 118
1usp_A_1161usp   A     MSESELENOMETHIONINE E - 119
1usp_A_1161usp   A     GOLGLYCEROL V - 120
1usp_A_1161usp   A     GOLGLYCEROL C - 121
1usp_A_1161usp   A     GOLGLYCEROL P - 122
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gpu_A_1571gpu   A AC1CA BINDING SITE FOR CHAIN AD - 157
1gpu_A_1571gpu   A AC2THD BINDING SITE FOR CHAIN AE - 162
1usp_A_1161usp   A AC1GOL BINDING SITE FOR CHAIN AP - 122

Clusters included in this Subclass
CLUSTER: HH.0.9
CLUSTER: HH.1.5
CLUSTER: HH.1.53
CLUSTER: HH.1.65
CLUSTER: HH.2.193
CLUSTER: HH.2.9
CLUSTER: HH.3.6