ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 1.2.17

Subclass Accession number: 2095
Subclass: 1.2.17

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
GO : GO:0005344 (>75 %)
SCOP : 46457 (>50 %) 46458 (>50 %) 46463 (>50 %)

Number of loops: 6

Average sequence ID (%) : 12.3 +/- 12.9
Average RMSD (Å) : 0.550 +/- 0.176

Consensus geometry

d (Å): 11

delta (°): 45-90

theta (°): 135-180

rho (°): 90-135

Consensus Sequence:	hDcXX
(φψ)-conformation:	aabaa

Pattern:	[fgkmt]	x	[AIKL]	[AILV]	[aenqs]	[ehkn]	[filmw]	[iklv]	[DKNR]	[EHNQSY]	[ailm]	[DS]	[DEN]	[ADPQ]	[ADEGK]	[aef]	[ILV]	x	[egkt]	x	[acglv]	[aek]	[dekqt]	[FHLY]	[AGS]
Conservation:	-1.169	-1.343	-0.365	0.703	-0.572	-0.306	-0.646	-0.438	0.448	-0.049	-0.185	2.834	2.020	0.416	-0.181	-0.487	1.557	-0.746	-0.865	-0.136	-1.219	-0.068	-0.472	0.398	0.872

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1b0b_*_59	1b0b	-	69	93	KGLVSNWVDNLDNAGALEGQCKTFA	HHHHHHHHTTTT-HHHHHHHHHHHH	aaaaaaaaaaaabaaaaaaaaaaaa
1h97_A_61	1h97	A	71	95	TEAIVHMLKEISNDAEVKKIAAQYG	HHHHHHHHTTTT-HHHHHHHHHHHH	aaaaaaaaaaaabaaaaaaaaaaaa
1hrd_A_2	1hrd	A	6	30	RVIAEVEKKYADEPEFVQTVEEVLS	HHHHHHHHHTTT-HHHHHHHHHHHH	aaaaaaaaaaaabaaaaaaaaaaaa
1it2_A_66	1it2	A	76	100	FNKVNEIINSMDNQEEIIKSLKDLS	HHHHHHHHTTTT-HHHHHHHHHHHH	aaaaaaaaaaaabaaaaaaaaaaaa
1v93_A_230	1v93	A	230	254	GPLLAKLERHQDDPKAVLEIGVEHA	HHHHHHHHHTTT-HHHHHHHHHHHH	aaaaaaaaaaaabaaaaaaaaaaaa
3sdh_A_64	3sdh	A	74	98	MYALQNFIDQLDNPDDLVCVVEKFA	HHHHHHHHHTTT-HHHHHHHHHHHH	aaaaaaaaaaaabaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1b0b_*_59	1b0b	*	HEMPROTOPORPHYRIN IX CONTAINING FE	Q - 64
1b0b_*_59	1b0b	*	CYNCYANIDE ION	Q - 64
1b0b_*_59	1b0b	*	HEMPROTOPORPHYRIN IX CONTAINING FE	S - 67
1b0b_*_59	1b0b	*	CYNCYANIDE ION	S - 67
1b0b_*_59	1b0b	*	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 68
1b0b_*_59	1b0b	*	CYNCYANIDE ION	F - 68
1b0b_*_59	1b0b	*	HEMPROTOPORPHYRIN IX CONTAINING FE	K - 69
1b0b_*_59	1b0b	*	HEMPROTOPORPHYRIN IX CONTAINING FE	G - 70
1b0b_*_59	1b0b	*	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 71
1b0b_*_59	1b0b	*	HEMPROTOPORPHYRIN IX CONTAINING FE	V - 72
1b0b_*_59	1b0b	*	HEMPROTOPORPHYRIN IX CONTAINING FE	W - 75
1b0b_*_59	1b0b	*	HEMPROTOPORPHYRIN IX CONTAINING FE	T - 91
1b0b_*_59	1b0b	*	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 92
1b0b_*_59	1b0b	*	HEMPROTOPORPHYRIN IX CONTAINING FE	N - 95
1b0b_*_59	1b0b	*	HEMPROTOPORPHYRIN IX CONTAINING FE	H - 96
1b0b_*_59	1b0b	*	CYNCYANIDE ION	H - 96
1h97_A_61	1h97	A	HEMPROTOPORPHYRIN IX CONTAINING FE	H - 65
1h97_A_61	1h97	A	HEMPROTOPORPHYRIN IX CONTAINING FE	Y - 66
1h97_A_61	1h97	A	HEMPROTOPORPHYRIN IX CONTAINING FE	T - 69
1h97_A_61	1h97	A	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 70
1h97_A_61	1h97	A	HEMPROTOPORPHYRIN IX CONTAINING FE	A - 73
1h97_A_61	1h97	A	HEMPROTOPORPHYRIN IX CONTAINING FE	I - 74
1h97_A_61	1h97	A	HEMPROTOPORPHYRIN IX CONTAINING FE	M - 77
1h97_A_61	1h97	A	HEMPROTOPORPHYRIN IX CONTAINING FE	Y - 94
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	E - 67
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	H - 70
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	Q - 71
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	V - 74
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	I - 75
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 76
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	K - 78
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	V - 79
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	I - 82
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 96
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 99
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	K - 102
1it2_A_66	1it2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	H - 103
1v93_A_230	1v93	A	DOXDIOXANE	K - 235
1v93_A_230	1v93	A	DOXDIOXANE	H - 239
1v93_A_230	1v93	A	DOXDIOXANE	D - 242
1v93_A_230	1v93	A	DOXDIOXANE	K - 244
1v93_A_230	1v93	A	DOXDIOXANE	A - 245
1v93_A_230	1v93	A	DOXDIOXANE	V - 246
1v93_A_230	1v93	A	DOXDIOXANE	E - 248
1v93_A_230	1v93	A	DOXDIOXANE	I - 249
1v93_A_230	1v93	A	DOXDIOXANE	V - 258
1v93_A_230	1v93	A	DOXDIOXANE	L - 262
1v93_A_230	1v93	A	DOXDIOXANE	E - 263
3sdh_A_64	3sdh	A	HEMPROTOPORPHYRIN IX CONTAINING FE	H - 69
3sdh_A_64	3sdh	A	HEMPROTOPORPHYRIN IX CONTAINING FE	T - 72
3sdh_A_64	3sdh	A	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 73
3sdh_A_64	3sdh	A	HEMPROTOPORPHYRIN IX CONTAINING FE	A - 76
3sdh_A_64	3sdh	A	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 77
3sdh_A_64	3sdh	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 80
3sdh_A_64	3sdh	A	HEMPROTOPORPHYRIN IX CONTAINING FE	K - 96
3sdh_A_64	3sdh	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 97
3sdh_A_64	3sdh	A	HEMPROTOPORPHYRIN IX CONTAINING FE	N - 100
3sdh_A_64	3sdh	A	HEMPROTOPORPHYRIN IX CONTAINING FE	H - 101

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1h97_A_61	1h97	A	HEAHEM BINDING SITE FOR CHAIN A	H - 65
1h97_A_61	1h97	A	HEAHEM BINDING SITE FOR CHAIN A	Y - 66

Clusters included in this Subclass

CLUSTER: HH.4.109

CLUSTER: HH.5.65