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Information on SUBCLASS 2.2.6
Subclass Accession number: 2212
Subclass: 2.2.6 PSSM
Type: HH alpha-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
GO : GO:0004553 (>75 %)  GO:0004553 (>75 %)  GO:0016798 (>50 %)  GO:0016798 (>50 %)  
SCOP : 48207 (>75 %)  48207 (>75 %)  56600 (>75 %)  56601 (>75 %)  56602 (>75 %)  
 Number of loops: 15

Average sequence ID (%) : 16.8 +/- 18.1
Average RMSD (Å) : 0.607 +/- 0.231

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: hphpXX
(φψ)-conformation: aalpaa
Pattern: [afgklmt]xxxx[afklv][krst][agqr][DEHKNS]xx[fglpy][afilv][adekt]
Conservation:-0.676-0.837-0.475-0.319-0.916-0.1961.1761.9381.939-1.080-0.172-0.590-0.1910.400
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1dl2_A_4351dl2   A441454MFMYHLSHDHKYREHHHHHHH--THHHHaaaaaaavxaaaaa
1fo3_A_4021fo3   A406419RELSRLTGDKKFQEHHHHHHH--THHHHaaaaaaavxaaaaa
1fo3_A_5991fo3   A605618FYLYRVTGDRKYQDHHHHHHH--THHHHaaaaaaavxaaaaa
1g5a_A_3511g5a   A357370LWNTLATREVNLLHHHHHHHH---HHHHaaaaaaavbaaaaa
1g9g_A_541g9g   A6578AMHGRFSGDFTGFDHHHHHHHS--HHHHaaaaaaavbaaaaa
1k9x_A_4441k9x   A444457FEEKVAKAEFDPIKHHHHHHHT--HHHHaaaaaaavxaaaaa
1kre_A_2031kre   A207220TRLSDLTGDEEYAKHHHHHHHS-THHHHaaaaaaavxaaaaa
1n93_X_1301n93   X143156LLIGVVIGSSSKIKHHHHHHHT-SHHHHaaaaaaavbaaaaa
1nc5_A_1431nc5   A153166LKYANLKQETELFDHHHHHHHT-THHHHaaaaaaalbaaaaa
1nxc_A_3561nxc   A360373MHLSHLSGDPVFAEHHHHHHH--THHHHaaaaaaavxaaaaa
1pfv_A_2521pfv   A265278KNLCDKRGDSVSFDHHHHHHHT-SSHHHaaaaaaavxaaaaa
1qaz_A_801qaz   A98111GNLYVATGKPVYATHHHHHHH--THHHHaaaaaaavxwaaaa
1r7a_A_2551r7a   A259272LLHALSTGHVEPVAHHHHHHH---HHHHaaaaaaavxaaaaa
1rh1_A_4201rh1   A431444SIEGYQTGNWGPLMHHHHHSSS--HHHHaaxgaaavbaaaaa
1ut9_A_6801ut9   A692705GYAYDFTGDSKYLDHHHHHHH--THHHHaaaaaaavxaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1dl2_A_4351dl2   A     CACALCIUM ION E - 435
1dl2_A_4351dl2   A     GOLGLYCEROL E - 435
1dl2_A_4351dl2   A     CACALCIUM ION E - 438
1fo3_A_5991fo3   A     KIFKIFUNENSINE E - 599
1fo3_A_5991fo3   A     CACALCIUM ION E - 599
1fo3_A_5991fo3   A     KIFKIFUNENSINE E - 602
1fo3_A_5991fo3   A     CACALCIUM ION E - 602
1g9g_A_541g9g   A     MGMAGNESIUM ION E - 55
1pfv_A_2521pfv   A     2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE W - 253
1pfv_A_2521pfv   A     2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE D - 255
1pfv_A_2521pfv   A     2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE A - 256
1pfv_A_2521pfv   A     2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE P - 257
1pfv_A_2521pfv   A     2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE I - 258
1pfv_A_2521pfv   A     2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE G - 259
1pfv_A_2521pfv   A     2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE Y - 260

Clusters included in this Subclass
CLUSTER: HH.2.165
CLUSTER: HH.3.56
CLUSTER: HH.4.26