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PDB code:

Information on SUBCLASS 2.2.8

Subclass Accession number: 2214 Subclass: 2.2.8 Type: HH alpha-alpha DB: ArchDB40 Image coordinates: Consensus coordinates: Conserved Annotation EC : 3 (>75 %)

Number of loops: 8 Average sequence ID (%) : 8.7 +/- 9.6 Average RMSD (Å) : 0.425 +/- 0.128 Consensus geometry d (Å): 7 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1c02_A_56	1c02	A	61	89	NLGHFLKGSSAALGLQRIAWVCERIQNLG	HHHHHHHHHHHHTT-HHHHHHHHHHHHHH	aaaaaaaaaaaaavxaaaaaaaaaaaaaa
1fpo_A_111	1fpo	A	126	154	DTRHQLMVEQLDNETWDAAADTCRKLRFL	HHHHHHHHHHHHTT-HHHHHHHHHHHHHH	aaaaaaaaaaaaavxaaaaaaaaaaaaaa
1h6g_A_398	1h6g	A	398	426	NVPLLVLIEAAKNGNEKEVKEYAQVFREH	HHHHHHHHHHHHTT-HHHHHHHHHHHHHH	aaaaaaaaaaaaalbaaaaaaaaaaaaaa
1j5w_A_206	1j5w	A	214	242	DEYEKEFYRLVEKNLYLPAYDYILKCSHT	HHHHHHHHHHHHTT-HHHHHHHHHHHHHH	aaaaaaaaaaaaavxaaaaaaaaaaaaaa
1k75_A_397	1k75	A	402	430	ALASTIETLAAAERLTAHKNAVTLRVNAL	HHHHHHHHHHHHTT-HHHHHHHHHHHHHH	aaaaaaaaaaaaalbaaaaaaaaaaaaaa
1umn_A_111	1umn	A	127	155	ALFQKGFDVSDEEGDSVTNDIFNVAKASI	HHHHHHHHHHHHHT-HHHHHHHHHHHHHH	aaaaaaaaaaaaavxaaaaaaaaaaaaaa
2a0b_*_677	2a0b	-	692	720	PGYVSVLESNLTAQDKKGIVEEGHKIKGA	HHHHHHHHHHHHTT-HHHHHHHHHHHHHH	aaaaaaaaaaaaalxaaaaaaaaaaaaaa
2e2a_A_3	2e2a	A	21	49	RSKLLEALKAAENGDFAKADSLVVEAGSC	HHHHHHHHHHHHTT-HHHHHHHHHHHHHH	aaaaaaaaaaaaavxaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1h6g_A_398	1h6g	A	MSESELENOMETHIONINE	L - 401
1h6g_A_398	1h6g	A	MSESELENOMETHIONINE	L - 404
1h6g_A_398	1h6g	A	MSESELENOMETHIONINE	I - 405
1h6g_A_398	1h6g	A	CACALCIUM ION	I - 405
1h6g_A_398	1h6g	A	MSESELENOMETHIONINE	A - 408
1j5w_A_206	1j5w	A	MSESELENOMETHIONINE	F - 213
1j5w_A_206	1j5w	A	MSESELENOMETHIONINE	Y - 216
1j5w_A_206	1j5w	A	MSESELENOMETHIONINE	E - 217
1j5w_A_206	1j5w	A	MSESELENOMETHIONINE	F - 220
1j5w_A_206	1j5w	A	MSESELENOMETHIONINE	Y - 221
1j5w_A_206	1j5w	A	MSESELENOMETHIONINE	V - 224
1j5w_A_206	1j5w	A	MSESELENOMETHIONINE	D - 234
1j5w_A_206	1j5w	A	MSESELENOMETHIONINE	Y - 235
1j5w_A_206	1j5w	A	MSESELENOMETHIONINE	I - 236
1j5w_A_206	1j5w	A	MSESELENOMETHIONINE	L - 237
1j5w_A_206	1j5w	A	MSESELENOMETHIONINE	K - 238
1j5w_A_206	1j5w	A	MSESELENOMETHIONINE	C - 239
1k75_A_397	1k75	A	MSESELENOMETHIONINE	T - 406
1k75_A_397	1k75	A	MSESELENOMETHIONINE	L - 410
1umn_A_111	1umn	A	EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	E - 112
1umn_A_111	1umn	A	EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	E - 165

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
2a0b_*_677	2a0b	*	PHBPHOSPHORYLATION SITE.	H - 715

Clusters included in this Subclass

CLUSTER: HH.2.83

CLUSTER: HH.3.79

CLUSTER: HH.4.73

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