ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 2.6.1

Subclass Accession number: 2249
Subclass: 2.6.1

PSSM

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Number of loops: 13

Average sequence ID (%) : 23.8 +/- 20.6
Average RMSD (Å) : 0.546 +/- 0.240

Consensus geometry

d (Å): 7

delta (°): 45-90

theta (°): 45-90

rho (°): 0-45

Consensus Sequence:	pXGGhX
(φψ)-conformation:	aageaa

Pattern:	x	[filvy]	[aegkqrs]	x	x	[G]	[AG]	[ilmptv]	[adepqst]	[aegkqrt]	[afilmv]	x
Conservation:	-0.683	-0.097	-0.204	-0.381	-0.625	2.395	1.754	-0.450	-0.285	-0.516	-0.161	-0.747

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1bjn_A_243	1bjn	A	255	266	WLKANGGVAEMD	HHHHTTHHHHHH	aaaaageaaaaa
1bue_A_132	1bue	A	139	150	LERYIGGPEGMT	HHHTT-HHHHHH	aaaaaveaaaaa
1dja_*_132	1dja	-	138	149	IIKEIGGIKKVK	HHHHHT-HHHHH	aaaaageaaaaa
1e25_A_132	1e25	A	138	149	LFELVGGPAALH	HHHHHTHHHHHH	aaaaageaaaaa
1m32_A_245	1m32	A	257	268	ELAKEGGVAARH	HHHHHTHHHHHH	aaaaageaaaaa
1m3q_A_204	1m3q	A	215	226	ILEEQGGLAWLQ	HHHTS-SHHHHH	aaaaageaaaaa
1o7e_B_132	1o7e	B	138	149	LFGVVGGPPAVT	HHHHHTSHHHHH	aaaaageaaaaa
1ojj_A_321	1ojj	A	322	333	KYMELGATQGMG	HHHHTTHHHHHH	aaaaaNeaaaaa
1pq1_A_179	1pq1	A	181	192	WIQENGGWDTFV	HHHHTTHHHHHH	aaaaaveaaaaa
1q2b_A_342	1q2b	A	342	353	SFSDKGGLTQFK	HHHHTTHHHHHH	aaaaageaaaaa
1s3e_A_182	1s3e	A	188	199	YVKQCGGTTRII	HHHTTT-HHHHH	aaaaageaaaaa
7req_A_407	7req	A	426	437	EVEKVGGMAKAI	HHHHTT-HHHHH	aaaaageaaaaa
7req_B_403	7req	B	422	433	EVEKLGGMSKAV	HHHHTT-HHHHH	aaaaageaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1m32_A_245	1m32	A	MSESELENOMETHIONINE	H - 246
1m32_A_245	1m32	A	MSESELENOMETHIONINE	T - 247
1m32_A_245	1m32	A	MSESELENOMETHIONINE	L - 249
1m32_A_245	1m32	A	MSESELENOMETHIONINE	A - 250
1m32_A_245	1m32	A	MSESELENOMETHIONINE	V - 264
1m32_A_245	1m32	A	MSESELENOMETHIONINE	S - 277
1m32_A_245	1m32	A	MSESELENOMETHIONINE	L - 278
1m32_A_245	1m32	A	MSESELENOMETHIONINE	V - 279
1m32_A_245	1m32	A	MSESELENOMETHIONINE	A - 280
1o7e_B_132	1o7e	B	GOLGLYCEROL	N - 132
1o7e_B_132	1o7e	B	GOLGLYCEROL	R - 153
1o7e_B_132	1o7e	B	GOLGLYCEROL	A - 154
1o7e_B_132	1o7e	B	GOLGLYCEROL	S - 155
1s3e_A_182	1s3e	A	RHP(3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL	Y - 188
1s3e_A_182	1s3e	A	RHP(3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL	I - 198
1s3e_A_182	1s3e	A	RHP(3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL	I - 199

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1o7e_B_132	1o7e	B	AC1GOL BINDING SITE FOR CHAIN A	A - 154
1o7e_B_132	1o7e	B	AC2GOL BINDING SITE FOR CHAIN B	S - 155

Clusters included in this Subclass

CLUSTER: HH.1.58

CLUSTER: HH.2.61

CLUSTER: HH.3.69

CLUSTER: HH.4.207