ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 2.6.2

Subclass Accession number: 2250
Subclass: 2.6.2

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
GO : GO:0005344 (>75 %) GO:0005344 (>75 %)
SCOP : 46457 (>75 %) 46457 (>75 %) 46458 (>75 %) 46458 (>75 %) 46459 (>75 %) 46459 (>75 %)

Number of loops: 5

Average sequence ID (%) : 28.2 +/- 22.1
Average RMSD (Å) : 0.500 +/- 0.200

Consensus geometry

d (Å): 9

delta (°): 90-135

theta (°): 90-135

rho (°): 0-45

Consensus Sequence:	XhGGXp
(φψ)-conformation:	aageaa

Pattern:	[FIL]	[EFY]	[ADEQ]	x	[ILV]	[G]	[G]	[hpqr]	[AEK]	[AIT]	[FIV]	x	[AGV]	[AFIV]	[LTV]	[ADEKS]	[ADKQR]	[FY]	[VY]	[aen]	[KNQR]	[FIV]
Conservation:	0.053	0.033	-0.418	-0.942	0.335	2.368	2.368	-1.005	-0.150	-0.534	-0.084	-0.723	-0.457	-0.537	-0.205	-0.738	-0.859	1.695	0.930	-1.089	-0.092	0.051

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1dlw_A_2	1dlw	A	2	23	LFEQLGGQAAVQAVTAQFYANI	HHHHTTSHHHHHHHHHHHHHHH	aaaaageaaaaaaaaaaaaaaa
1dly_A_2	1dly	A	2	23	LFAKLGGREAVEAAVDKFYNKI	HHHHTTHHHHHHHHHHHHHHHH	aaaaageaaaaaaaaaaaaaaa
1hs6_A_381	1hs6	A	393	414	LEQLLGGPEIFLGFLKAYVEKF	HHHHTT-HHHHHHHHHHHHHHH	aaaaageaaaaaaaaaaaaaaa
1idr_A_15	1idr	A	15	36	IYDKIGGHEAIEVVVEDFYVRV	HHHHTTHHHHHHHHHHHHHHHH	aaaaageaaaaaaaaaaaaaaa
1ngk_A_5	1ngk	A	5	26	FYDAVGGAKTFDAIVSRFYAQV	HHHHTTTHHHHHHHHHHHHHHH	aaaaageaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1dlw_A_2	1dlw	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 19
1dlw_A_2	1dlw	A	HEMPROTOPORPHYRIN IX CONTAINING FE	Y - 20
1dly_A_2	1dly	A	CYNCYANIDE ION	F - 19
1dly_A_2	1dly	A	CYNCYANIDE ION	Y - 20
1hs6_A_381	1hs6	A	ZNZINC ION	Y - 383
1hs6_A_381	1hs6	A	BES2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID	Y - 383
1idr_A_15	1idr	A	OXYOXYGEN MOLECULE	F - 32
1idr_A_15	1idr	A	HEMPROTOPORPHYRIN IX CONTAINING FE	Y - 33
1idr_A_15	1idr	A	OXYOXYGEN MOLECULE	Y - 33
1ngk_A_5	1ngk	A	CNCYANIDE GROUP	F - 22
1ngk_A_5	1ngk	A	HEMPROTOPORPHYRIN IX CONTAINING FE	Y - 23
1ngk_A_5	1ngk	A	CNCYANIDE GROUP	Y - 23

Clusters included in this Subclass

CLUSTER: HH.2.128