ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 3.4.4

Subclass Accession number: 2312
Subclass: 3.4.4

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Number of loops: 17

Average sequence ID (%) : 9.8 +/- 11.5
Average RMSD (Å) : 0.676 +/- 0.217

Consensus geometry

d (Å): 11

delta (°): 45-90

theta (°): 135-180

rho (°): 135-180

Consensus Sequence:	XpXXpXX
(φψ)-conformation:	aapapaa

Pattern:	x	[adegknr]	x	[ACFILTV]	x	[adeknrs]	[acfiklmtv]	x	[DHNRST]	x	[aegnqrs]	[adegkqt]	x	x	x	[ilmvy]
Conservation:	-0.655	0.340	-1.224	1.544	-0.555	1.320	-0.549	-0.795	1.843	-1.041	0.004	-0.081	-0.718	-0.739	-0.118	1.423

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1al3_*_297	1al3	-	300	315	VDTAVALRSNEDIEAM	HHHHHH---HHHHHHH	aaaaaapaxaaaaaaa
1ca1_*_174	1ca1	-	176	191	YADILKNKDFNAWSKE	HHHHHH-S-HHHHHHH	aaaaaaxaxaaaaaaa
1cy5_A_37	1cy5	A	40	55	EEKVRNEPTQQQRAAM	HHHHHTSSSHHHHHHH	aaaaaaxabaaaaaaa
1ezv_C_276	1ezv	C	279	294	YAILRSIPDKLLGVIT	HHHHHTSSSHHHHHHH	aaaaaababaaaaaaa
1gz3_A_61	1gz3	A	69	84	HRNLKKMTSPLEKYIY	HHHHHT---HHHHHHH	aaaaaaxaxaaaaaaa
1jj2_O_28	1jj2	O	28	43	QGDIADAITREDVREL	HHHHHT--SHHHHHHH	aaaaaaxabaaaaaaa
1k87_A_161	1k87	A	169	184	AEALLRIPDKATRDAL	HHHHHTSS-HHHHHHH	aaaaaaxabaaaaaaa
1lla_*_51	1lla	-	61	76	YEVFWEAGDFNDFIEI	HHHHHT-SSHHHHHHH	aaaaaaxabaaaaaaa
1mty_G_10	1mty	G	16	31	VNKIAHVNTLEKAAEM	HHHHHT--SHHHHHHH	aaaaaaxabaaaaaaa
1mzg_A_7	1mzg	A	11	26	LRNFLRCANWEEKYLY	HHHHHH-SSHHHHHHH	aaaaaapabaaaaaaa
1nvu_S_819	1nvu	S	836	851	EKCIVETENLEERVAV	HHHHHT--SHHHHHHH	aaaaaabaxaaaaaaa
1p80_A_517	1p80	A	528	543	SFELSKVVRPYIRERV	HHHHHT-SSHHHHHHH	aaaaaaxaxaaaaaaa
1qls_A_46	1qls	A	46	61	AAFTQNQKDPGVLDRM	HHHHHH---THHHHHH	aaaaaapaxaaaaaaa
1qr0_A_26	1qr0	A	29	44	REKCRRFYHKEDAHRT	HHHHHH-SSHHHHHHH	aaaaaaxaxaaaaaaa
1r3c_A_244	1r3c	A	244	259	AELLKKISSESARNYI	HHHHHH---HHHHHHH	aaaaaaxapaaaaaaa
1s9r_A_108	1s9r	A	115	130	RNFLKAKKTSRELVEI	HHHHHT-SSHHHHHHH	aaaaaaxabaaaaaaa
1v9m_A_121	1v9m	A	124	139	WRQAYEAQDPAGMAQV	HHHHHHSSSHHHHHHH	aaaaaapabaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ca1_*_174	1ca1	*	CDCADMIUM ION	D - 174
1ca1_*_174	1ca1	*	CDCADMIUM ION	F - 175
1ca1_*_174	1ca1	*	CDCADMIUM ION	D - 178
1ca1_*_174	1ca1	*	CDCADMIUM ION	L - 180
1ca1_*_174	1ca1	*	CDCADMIUM ION	K - 181
1cy5_A_37	1cy5	A	ZNZINC ION	I - 37
1cy5_A_37	1cy5	A	ZNZINC ION	E - 40
1cy5_A_37	1cy5	A	ZNZINC ION	E - 41
1cy5_A_37	1cy5	A	ZNZINC ION	K - 42
1cy5_A_37	1cy5	A	ZNZINC ION	N - 45
1cy5_A_37	1cy5	A	ZNZINC ION	Q - 50
1cy5_A_37	1cy5	A	ZNZINC ION	A - 54
1ezv_C_276	1ezv	C	SMASTIGMATELLIN A	F - 278
1ezv_C_276	1ezv	C	SMASTIGMATELLIN A	Y - 279
1ezv_C_276	1ezv	C	SMASTIGMATELLIN A	L - 282
1ezv_C_276	1ezv	C	SMASTIGMATELLIN A	M - 295
1ezv_C_276	1ezv	C	SMASTIGMATELLIN A	F - 296
1ezv_C_276	1ezv	C	SMASTIGMATELLIN A	I - 299
1gz3_A_61	1gz3	A	FUMFUMARIC ACID	I - 63
1gz3_A_61	1gz3	A	FUMFUMARIC ACID	Q - 64
1gz3_A_61	1gz3	A	FUMFUMARIC ACID	A - 65
1gz3_A_61	1gz3	A	FUMFUMARIC ACID	R - 67
1gz3_A_61	1gz3	A	FUMFUMARIC ACID	F - 68
1gz3_A_61	1gz3	A	FUMFUMARIC ACID	Y - 84
1gz3_A_61	1gz3	A	FUMFUMARIC ACID	G - 87
1gz3_A_61	1gz3	A	FUMFUMARIC ACID	I - 88
1k87_A_161	1k87	A	1PEPENTAETHYLENE GLYCOL	E - 170
1k87_A_161	1k87	A	1PEPENTAETHYLENE GLYCOL	R - 174
1mzg_A_7	1mzg	A	MSESELENOMETHIONINE	K - 7
1mzg_A_7	1mzg	A	MSESELENOMETHIONINE	L - 10
1mzg_A_7	1mzg	A	MSESELENOMETHIONINE	L - 11
1mzg_A_7	1mzg	A	MSESELENOMETHIONINE	F - 14
1mzg_A_7	1mzg	A	MSESELENOMETHIONINE	L - 15
1mzg_A_7	1mzg	A	MSESELENOMETHIONINE	W - 20
1mzg_A_7	1mzg	A	MSESELENOMETHIONINE	K - 23
1mzg_A_7	1mzg	A	MSESELENOMETHIONINE	I - 27
1nvu_S_819	1nvu	S	PO4PHOSPHATE ION	L - 822
1nvu_S_819	1nvu	S	PO4PHOSPHATE ION	R - 826
1qls_A_46	1qls	A	CACALCIUM ION	L - 65
1qr0_A_26	1qr0	A	COACOENZYME A	K - 28
1qr0_A_26	1qr0	A	COACOENZYME A	K - 31
1qr0_A_26	1qr0	A	COACOENZYME A	F - 35
1qr0_A_26	1qr0	A	COACOENZYME A	R - 43
1qr0_A_26	1qr0	A	COACOENZYME A	T - 44
1qr0_A_26	1qr0	A	COACOENZYME A	L - 45
1qr0_A_26	1qr0	A	COACOENZYME A	G - 47

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1ca1_*_174	1ca1	*	CD7CD FROM CRYSTALLISATION BUFFER AT PROTEIN SURFACE.	D - 174
1ca1_*_174	1ca1	*	CD7CD FROM CRYSTALLISATION BUFFER AT PROTEIN SURFACE.	D - 178
1gz3_A_61	1gz3	A	AC4FUM BINDING SITE FOR CHAIN A	Q - 64
1gz3_A_61	1gz3	A	AC4FUM BINDING SITE FOR CHAIN A	R - 67

Clusters included in this Subclass