ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 3.5.3

Subclass Accession number: 2321
Subclass: 3.5.3

PSSM

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Number of loops: 7

Average sequence ID (%) : 9.5 +/- 11.5
Average RMSD (Å) : 0.857 +/- 0.230

Consensus geometry

d (Å): 11

delta (°): 45-90

theta (°): 135-180

rho (°): 315-360

Consensus Sequence:	pXXXcXX
(φψ)-conformation:	aabapaa

Pattern:	[adekr]	[ael]	[AILV]	x	[dekrt]	x	x	[kqrsw]	[DGNT]	x	[agkv]	x	x	[eqs]	x	x
Conservation:	-0.094	-0.091	2.108	-0.834	-0.231	-0.948	-0.507	-0.288	2.219	-1.249	-0.043	-0.393	-0.282	1.262	-0.176	-0.453

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a28_A_838	1a28	A	854	869	KAIGLRQKGVVSSSQR	HHHHTT--SHHHHHHH	aaaaaabapaaaaaaa
1f5m_A_21	1f5m	A	33	48	EGLSDGQVNWVCNLSN	HHHHTT--BHHHHHHH	aaaaaabapaaaaaaa
1h0o_A_157	1h0o	A	179	194	LLIDTYIKDPKEREYL	HHHHHH---HHHHHHH	aaaaaabaxaaaaaaa
1o7e_B_24	1o7e	B	24	39	DAAITAASDFAALEKA	HHHHHH--SHHHHHHH	aaaaaaxabaaaaaaa
1s3e_A_148	1s3e	A	150	165	ELLDKLCWTESAKQLA	HHHHHH-SSHHHHHHH	aaaaaaxabaaaaaaa
1v9m_A_146	1v9m	A	152	167	RAVLRETQDLARVEAL	HHHHTT---HHHHHHH	aaaaaabaxaaaaaaa
1vh4_A_382	1vh4	A	395	410	AELTEALRDEGLKQQV	HHHHTT---HHHHHHH	aaaaaaxaxaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1a28_A_838	1a28	A	STRPROGESTERONE	L - 887
1a28_A_838	1a28	A	STRPROGESTERONE	Y - 890
1a28_A_838	1a28	A	STRPROGESTERONE	C - 891
1a28_A_838	1a28	A	STRPROGESTERONE	L - 892
1a28_A_838	1a28	A	STRPROGESTERONE	T - 894
1a28_A_838	1a28	A	STRPROGESTERONE	F - 895
1h0o_A_157	1h0o	A	COCOBALT (II) ION	Q - 166
1h0o_A_157	1h0o	A	COCOBALT (II) ION	E - 170
1h0o_A_157	1h0o	A	COCOBALT (II) ION	H - 173
1s3e_A_148	1s3e	A	RHP(3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL	F - 168
1s3e_A_148	1s3e	A	RHP(3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL	L - 171
1s3e_A_148	1s3e	A	RHP(3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL	C - 172
1s3e_A_148	1s3e	A	RHP(3R)-3-(PROP-2-YNYLAMINO)INDAN-5-OL	V - 173
1v9m_A_146	1v9m	A	GOLGLYCEROL	P - 146
1v9m_A_146	1v9m	A	GOLGLYCEROL	R - 149
1v9m_A_146	1v9m	A	GOLGLYCEROL	D - 175

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1h0o_A_157	1h0o	A	CO1CO BINDING SITE FOR CHAIN A	Q - 166
1h0o_A_157	1h0o	A	CO1CO BINDING SITE FOR CHAIN A	E - 170
1o7e_B_24	1o7e	B	AC6SO4 BINDING SITE FOR CHAIN B	D - 24

Clusters included in this Subclass

CLUSTER: HH.4.69