ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.7.2

Subclass Accession number: 2385
Subclass: 4.7.2

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : - (>75 %)  - (>75 %)  1.4 (>75 %)  1.4.1 (>75 %)  1.4.1.3
GO : GO:0004353 (>75 %)  GO:0016638 (>75 %)  GO:0016639 (>75 %)
SCOP : 53222 (>75 %)  53223 (>75 %)  53224 (>75 %)

Number of loops: 2

Average sequence ID (%) : 13.2 +/- 0.0
Average RMSD (Å) : 1.100 +/- 0.000

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 135-180

rho (°): 180-225

Consensus Sequence:	hhGppXpX
(φψ)-conformation:	aalbbbaa

Pattern:	[FR]	[FW]	[LT]	[I]	[AT]	[FV]	[GQ]	[HL]	[KR]	[AG]	[LM]	[AV]	[AE]	[GY]	[AS]	[AK]	[FH]	[A]	[DT]	[AV]	[LV]	[G]	[KS]	[HS]	[CE]	[NS]	[SW]	[CL]	[D]	[AS]	[FQ]	[AM]	[PQ]	[EQ]	[AI]	[L]	[AC]	[KY]
Conservation:	-1.200	1.812	-0.770	1.166	-0.340	-0.555	-0.770	-0.985	0.736	-0.125	0.521	-0.555	-0.770	-0.770	-0.125	-0.770	0.306	1.166	-0.340	-0.555	-0.125	2.888	-0.340	-0.125	-0.985	0.306	-0.340	0.091	2.888	-0.125	-1.200	-0.770	-0.125	0.736	-0.985	1.166	0.521	-0.555

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1gai_*_186	1gai	-	186	223	FFTIAVQHRALVEGSAFATAVGSSCSWCDSQAPQILCY	HHHHHHHHHHHHHHHHHHHHTT---HHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaavbbbaaaaaaaaaaaaa
1gnl_A_137	1gnl	A	143	180	RWLITFGLKGMAAYAKHADVLGKHENSLDAFMQEALAK	HHHHHHHHHHHHHHHHHHHHTT---HHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaavbbbaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1gai_*_186	1gai	*	NAGN-ACETYL-D-GLUCOSAMINE	I - 189
1gai_*_186	1gai	*	MANALPHA-D-MANNOSE	S - 208
1gai_*_186	1gai	*	MANALPHA-D-MANNOSE	W - 212
1gai_*_186	1gai	*	MANALPHA-D-MANNOSE	S - 215
1gai_*_186	1gai	*	MANALPHA-D-MANNOSE	Q - 216
1gai_*_186	1gai	*	MANALPHA-D-MANNOSE	P - 218
1gai_*_186	1gai	*	MANALPHA-D-MANNOSE	Q - 219
1gai_*_186	1gai	*	NAGN-ACETYL-D-GLUCOSAMINE	Q - 219
1gai_*_186	1gai	*	MANALPHA-D-MANNOSE	L - 221
1gai_*_186	1gai	*	NAGN-ACETYL-D-GLUCOSAMINE	C - 222
1gai_*_186	1gai	*	NAGN-ACETYL-D-GLUCOSAMINE	Y - 223
1gnl_A_137	1gnl	A	FSOIRON/SULFUR/OXYGEN HYBRID CLUSTER	Y - 156

Clusters included in this Subclass

CLUSTER: HH.6.54