ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 4.10.2

Subclass Accession number: 2394
Subclass: 4.10.2

PSSM

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Conserved Annotation
EC : 1 (>75 %)
GO : GO:0004175 (>75 %) GO:0005524 (>75 %) GO:0008233 (>75 %) GO:0030554 (>75 %)

Number of loops: 4

Average sequence ID (%) : 13.9 +/- 13.1
Average RMSD (Å) : 1.075 +/- 0.189

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 90-135

rho (°): 315-360

Consensus Sequence:	XXXphXhc
(φψ)-conformation:	aabpbpaa

Pattern:	x	[QRSW]	x	x	x	x	x	[EKTW]	x	[CDS]	x	x	[ADER]	[L]	x	[AQ]	[ANS]	[IL]
Conservation:	-1.026	-0.479	-0.488	-0.601	-0.905	-0.844	-0.078	-0.540	0.068	0.323	0.162	-0.479	-0.297	2.863	-0.662	0.675	0.418	1.890

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a5t_*_169	1a5t	-	174	191	TWLSREVTMSQDALLAAL	HHHHHH----HHHHHHHH	aaaaaabbbxaaaaaaaa
1i6l_A_41	1i6l	A	41	58	DQHAITVWQDPHELRQNI	HHHHTTS---HHHHHHHH	aaaaaabpbxaaaaaaaa
1kiy_A_50	1kiy	A	50	67	PRQQQLLKVDPKRLQASL	HHHHHH----HHHHHHHH	aaaaaaxxbxaaaaaaaa
1smt_A_46	1smt	A	52	69	LSLLARSELCVGDLAQAI	HHHHTT--B-HHHHHHHH	aaaaaabxbxaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1i6l_A_41	1i6l	A	MSESELENOMETHIONINE	H - 43
1i6l_A_41	1i6l	A	TYMTRYPTOPHANYL-5'AMP	H - 43
1i6l_A_41	1i6l	A	GOLGLYCEROL	P - 51
1i6l_A_41	1i6l	A	GOLGLYCEROL	H - 52
1i6l_A_41	1i6l	A	GOLGLYCEROL	R - 55
1i6l_A_41	1i6l	A	MSESELENOMETHIONINE	Q - 56
1i6l_A_41	1i6l	A	GOLGLYCEROL	Q - 56
1i6l_A_41	1i6l	A	GOLGLYCEROL	N - 57
1i6l_A_41	1i6l	A	MSESELENOMETHIONINE	R - 59
1i6l_A_41	1i6l	A	GOLGLYCEROL	R - 59
1i6l_A_41	1i6l	A	MSESELENOMETHIONINE	R - 60
1i6l_A_41	1i6l	A	GOLGLYCEROL	R - 60
1i6l_A_41	1i6l	A	GOLGLYCEROL	L - 61
1i6l_A_41	1i6l	A	MSESELENOMETHIONINE	A - 63
1i6l_A_41	1i6l	A	GOLGLYCEROL	L - 64
1kiy_A_50	1kiy	A	EDO1,2-ETHANEDIOL	L - 55
1kiy_A_50	1kiy	A	EDO1,2-ETHANEDIOL	L - 56
1kiy_A_50	1kiy	A	EDO1,2-ETHANEDIOL	K - 57
1kiy_A_50	1kiy	A	EDO1,2-ETHANEDIOL	V - 58
1kiy_A_50	1kiy	A	EDO1,2-ETHANEDIOL	T - 69
1kiy_A_50	1kiy	A	EDO1,2-ETHANEDIOL	I - 70
1kiy_A_50	1kiy	A	EDO1,2-ETHANEDIOL	M - 73

Clusters included in this Subclass

CLUSTER: HH.5.130