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Information on SUBCLASS 5.4.1
Subclass Accession number: 2445
Subclass: 5.4.1 PSSM
Type: HH alpha-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
GO : GO:0005524 (>75 %)  GO:0016301 (>75 %)  GO:0016772 (>75 %)  GO:0030554 (>75 %)  
SCOP : 52539 (>75 %)  52540 (>75 %)  
 Number of loops: 20

Average sequence ID (%) : 11.5 +/- 13.2
Average RMSD (Å) : 0.810 +/- 0.302

Consensus geometry
d (Å): 11 delta (°): 45-90 theta (°): 135-180 rho (°): 180-225
Consensus Sequence: hXpXpXpXX
(φψ)-conformation: aapaappaa
Pattern: [adeknqrst]x[acfiklmtv]x[ADEKNRST]x[adeknqst]x[dhknpst]xxx[acfiklv]
Conservation:-0.025-1.3850.124-1.2472.314-0.1940.7920.0161.200-0.693-0.2130.035-0.725
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ak0_*_861ak0   -95107QRVSDSSLSSENHHHHT-TTS-HHHHaaaaxaaxxaaaa
1eex_A_841eex   A89101NMLCDPNVKRSEIHHHH-TTS-HHHHaaaaxaaxxaaaa
1ezf_A_641ezf   A8193TLEDDMTISVEKKHHHH-TTS-HHHHaaaaxaaxxaaaa
1f2e_A_1051f2e   A110122VPLFAPATSDEAKHHHH-SS--HHHHaaaaxaapxaaaa
1gnl_A_1681gnl   A179191AKTLDDSLSVADLHHTT-TT--HHHHaaaaxaaxxaaaa
1gux_A_5251gux   A535547FIKAEGNLTREMIHHHH-TT--HHHHaaaabaaxxaaaa
1h0o_A_2021h0o   A213225RWIGDKEATYGERHHHH-SSS-HHHHaaaaxaapxaaaa
1hu3_A_9581hu3   A958970KIVKERKTSSRIRHHHHS-SS-HHHHaaaaxaabpaaaa
1jlr_A_431jlr   A5062TIIRDKETPKEEFHHHH-TT--HHHHaaaaxaaxxaaaa
1kxp_D_4351kxp   D450462SNCCSINSPPLYCHHHSSTT--HHHHaaaabaaxxaaaa
1n1b_A_2581n1b   A264276AYARRPDMNPLIFHHHH-TT--HHHHaaaaxaapxaaaa
1nh1_A_2231nh1   A235247RQAISSDLSQAELHHHT-SS--HHHHaaaaxaaxxaaaa
1nm8_A_4521nm8   A459471KAMDDSSVTEHQKHHHT-TTS-HHHHaaaaxaabxaaaa
1nwc_A_1881nwc   A189201SELKDPASSILDIHHHH-TTS-HHHHaaaaxaaxxaaaa
1o5o_A_101o5o   A1729TIMRDKNTGPKEFHHHHSTT--HHHHaaaapaaxxaaaa
1odo_A_1611odo   A172184DGVFDTTLDQAEAHHHH-TT--HHHHaaaaxaaxxaaaa
1orj_A_10761orj   A10911103NTLVKVDKTKEELHHHH-TT--HHHHaaaapaaxbaaaa
1q06_A_601q06   A6880NLFNDPQRHSADVHHHH-TT--HHHHaaaaxaaxbaaaa
1qgr_A_1291qgr   A135147ANVTNPNSTEHMKHHHH-TT--HHHHaaaaxaapxaaaa
2pgd_*_2122pgd   -221233EWNKTELDSFLIEHHTTTTT-BHHHHaaaabaapbaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ak0_*_861ak0   *     NAGN-ACETYL-D-GLUCOSAMINE S - 88
1ak0_*_861ak0   *     NAGN-ACETYL-D-GLUCOSAMINE A - 89
1ak0_*_861ak0   *     NAGN-ACETYL-D-GLUCOSAMINE N - 92
1ak0_*_861ak0   *     NAGN-ACETYL-D-GLUCOSAMINE Y - 93
1ak0_*_861ak0   *     NAGN-ACETYL-D-GLUCOSAMINE R - 96
1ak0_*_861ak0   *     NAGN-ACETYL-D-GLUCOSAMINE N - 106
1ak0_*_861ak0   *     NAGN-ACETYL-D-GLUCOSAMINE E - 109
1ak0_*_861ak0   *     NAGN-ACETYL-D-GLUCOSAMINE F - 113
1ak0_*_861ak0   *     ZNZINC ION H - 116
1ak0_*_861ak0   *     ZNZINC ION F - 117
1ak0_*_861ak0   *     ZNZINC ION G - 119
1ak0_*_861ak0   *     ZNZINC ION D - 120
1ak0_*_861ak0   *     THSTHYMIDINE-5'-(DITHIO)PHOSPHATE D - 120
1ezf_A_641ezf   A     IN0N-{2-[TRANS-7-CHLORO-1-(2,2-DIMETHYL-PROPYL) -5-NAPHTHALEN-1-YL-2-OXO-1,2,3,5-TETRAHYDRO-BENZO[E] [1, 4]OXAZEPIN-3-YL]-ACETYL}-ASPARTIC ACID V - 69
1ezf_A_641ezf   A     IN0N-{2-[TRANS-7-CHLORO-1-(2,2-DIMETHYL-PROPYL) -5-NAPHTHALEN-1-YL-2-OXO-1,2,3,5-TETRAHYDRO-BENZO[E] [1, 4]OXAZEPIN-3-YL]-ACETYL}-ASPARTIC ACID F - 72
1ezf_A_641ezf   A     IN0N-{2-[TRANS-7-CHLORO-1-(2,2-DIMETHYL-PROPYL) -5-NAPHTHALEN-1-YL-2-OXO-1,2,3,5-TETRAHYDRO-BENZO[E] [1, 4]OXAZEPIN-3-YL]-ACETYL}-ASPARTIC ACID Y - 73
1ezf_A_641ezf   A     IN0N-{2-[TRANS-7-CHLORO-1-(2,2-DIMETHYL-PROPYL) -5-NAPHTHALEN-1-YL-2-OXO-1,2,3,5-TETRAHYDRO-BENZO[E] [1, 4]OXAZEPIN-3-YL]-ACETYL}-ASPARTIC ACID L - 76
1ezf_A_641ezf   A     IN0N-{2-[TRANS-7-CHLORO-1-(2,2-DIMETHYL-PROPYL) -5-NAPHTHALEN-1-YL-2-OXO-1,2,3,5-TETRAHYDRO-BENZO[E] [1, 4]OXAZEPIN-3-YL]-ACETYL}-ASPARTIC ACID R - 77
1ezf_A_641ezf   A     IN0N-{2-[TRANS-7-CHLORO-1-(2,2-DIMETHYL-PROPYL) -5-NAPHTHALEN-1-YL-2-OXO-1,2,3,5-TETRAHYDRO-BENZO[E] [1, 4]OXAZEPIN-3-YL]-ACETYL}-ASPARTIC ACID D - 80
1f2e_A_1051f2e   A     GTTGLUTATHIONE H - 106
1f2e_A_1051f2e   A     GTTGLUTATHIONE K - 107
1h0o_A_2021h0o   A     COCOBALT (II) ION E - 233
1h0o_A_2021h0o   A     COCOBALT (II) ION F - 237
1hu3_A_9581hu3   A     MSESELENOMETHIONINE K - 958
1hu3_A_9581hu3   A     MSESELENOMETHIONINE I - 959
1hu3_A_9581hu3   A     MSESELENOMETHIONINE V - 960
1hu3_A_9581hu3   A     MSESELENOMETHIONINE K - 961
1hu3_A_9581hu3   A     MSESELENOMETHIONINE S - 967
1hu3_A_9581hu3   A     MSESELENOMETHIONINE R - 968
1hu3_A_9581hu3   A     MSESELENOMETHIONINE I - 969
1hu3_A_9581hu3   A     MSESELENOMETHIONINE R - 970
1jlr_A_431jlr   A     GTPGUANOSINE-5'-TRIPHOSPHATE Q - 44
1jlr_A_431jlr   A     GTPGUANOSINE-5'-TRIPHOSPHATE K - 59
1jlr_A_431jlr   A     GTPGUANOSINE-5'-TRIPHOSPHATE E - 60
1jlr_A_431jlr   A     GTPGUANOSINE-5'-TRIPHOSPHATE F - 64
1jlr_A_431jlr   A     GTPGUANOSINE-5'-TRIPHOSPHATE Y - 65
1jlr_A_431jlr   A     GTPGUANOSINE-5'-TRIPHOSPHATE R - 68
1jlr_A_431jlr   A     GTPGUANOSINE-5'-TRIPHOSPHATE E - 75
1odo_A_1611odo   A     PIM4-PHENYL-1H-IMIDAZOLE V - 174
1odo_A_1611odo   A     PIM4-PHENYL-1H-IMIDAZOLE F - 175
1q06_A_601q06   A     AGSILVER ION S - 77
1q06_A_601q06   A     AGSILVER ION A - 78
1q06_A_601q06   A     AGSILVER ION V - 80
1q06_A_601q06   A     AGSILVER ION K - 81
1q06_A_601q06   A     AGSILVER ION L - 108
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1h0o_A_2021h0o   A CO1CO BINDING SITE FOR CHAIN AE - 233

Clusters included in this Subclass
CLUSTER: HH.4.183
CLUSTER: HH.4.284
CLUSTER: HH.5.192
CLUSTER: HH.5.29
CLUSTER: HH.6.49
CLUSTER: HH.6.8
CLUSTER: HH.8.18