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Information on SUBCLASS 1.1.6
Subclass Accession number: 2635
Subclass: 1.1.6 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 67

Average sequence ID (%) : 9.0 +/- 12.4
Average RMSD (Å) : 0.491 +/- 0.208

Consensus geometry
d (Å): 9 delta (°): 0-45 theta (°): 90-135 rho (°): 135-180
Consensus Sequence: XhXXX
(φψ)-conformation: bbpaa
Pattern: xxxx[acfgilmptv][adegnpqst]x[adegknqrst]x[acfgiklv]
Conservation:-1.000-1.0000.194-1.523-0.1081.883-0.8850.198-0.2200.461
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1aco_*_1771aco   -177186ICIGVGGADAEEEE--HHHHbbbxbxaaaa
1an8_*_501an8   -5160ISSEMSYEASEEEE--HHHHbbbxbxaaaa
1ayf_A_561ayf   A5664.HLIFEQHIF.EEE--HHHH.pbbxxaaaa
1bx4_A_161bx4   A1928ISAVVDKDFLEEEE--HHHHbbbxbbaaaa
1cuk_*_241cuk   -2635YEVHMPMTCFEEEE--HHHHxxbxbxaaaa
1d5t_A_451d5t   A4552..SITPLEEL..EE-SHHHH..bbbwaaaa
1dms_*_811dms   -8189.FVRVSWDQA.EEE--HHHH.bbxbxaaaa
1dp4_A_2091dp4   A210219IYICSSPDAFEEEES-HHHHbbbbbxaaaa
1dsz_A_11491dsz   A11491156..VSACEGCK..EE--HHHH..bxbxaaaa
1dsz_B_12491dsz   B12491256..VYSCEGCK..EE--HHHH..bpbxaaaa
1dxy_*_1871dxy   -187194..DYVSLEDL..EE--HHHH..bxbxaaaa
1ekr_A_241ekr   A3241AFVTMRSETLEEEE--HHHHbbbxbxaaaa
1eu1_A_811eu1   A8189.FVRVTWDEA.EEE--HHHH.bbxbxaaaa
1eu3_A_441eu3   A4857INSEMDEYAAEEEE--HHHHbbbxbpaaaa
1fts_*_4801fts   -480488.LRPFKADDF.EEE--HHHH.xxxxbaaaa
1g8k_A_1311g8k   A131139.WVDTTWDHA.EEE--HHHH.xbxbxaaaa
1gde_A_2431gde   A243252GFVAAPSWIIEEEE--HHHHbbbbbwaaaa
1gky_*_941gky   -95104CILDIDMQGVEEEE--HHHHxbbbbxaaaa
1gs5_A_1561gs5   A156164.LMNVNADQA.EEE--HHHH.xbxbpaaaa
1hsk_A_2071hsk   A207214..APGKMTEI..EE--HHHH..bwbbaaaa
1hsl_A_461hsl   A4655TFVENPLDALEEEE--HHHHbxxxbwaaaa
1i36_A_471i36   A4754..TETSEEDV..EE--HHHH..xxbxaaaa
1i6a_A_1201i6a   A123132YLHEAQTHQLEEEE--HHHHbbbbbxaaaa
1i7p_A_2681i7p   A270279ILMCGPPPMIEEEES-HHHHbbbbbpaaaa
1ile_*_1861ile   -186193..TPLSSHEV..EE--HHHH..bxbbaaaa
1j20_A_2311j20   A231238..ERLSPAAL..EE--HHHH..xxbxaaaa
1jdp_A_2121jdp   A213222VIMCASSDTIEEEES-HHHHbbbbbxaaaa
1jfl_A_1181jfl   A119128AGLLATTGTIEEEE--HHHHbxbbbxaaaa
1jmx_A_1121jmx   A112119..QRRPAKEW..EE--HHHH..bbbxaaaa
1jxh_A_1351jxh   A135143.LITPNLPEA.EEE-BHHHH.bbbxxaaaa
1k4t_A_5361k4t   A539548NKVPVEKRVFEEEE--HHHHbbbwbxaaaa
1ky8_A_3771ky8   A377386TLVEAPADRVEEEE--HHHHbbbxbxaaaa
1l1l_A_6901l1l   A690698.KEPIDKETY.EEE--HHHH.bbxbxaaaa
1l5j_A_8021l5j   A802811NVFLASAELAEEEE--HHHHbbxxbxaaaa
1li4_A_2581li4   A258265..EVTTMDEA..EE--HHHH..xbbxaaaa
1lvg_A_971lvg   A98107CVLDVDLQGVEEEE--HHHHxbbbbxaaaa
1m2k_A_2231m2k   A223232YSLRGKAGEVEEE-S-HHHHbbxxbxaaaa
1mza_A_1561mza   A159168TVTVLSRKLCEEEE--HHHHxbbxxxaaaa
1na6_A_3681na6   A368375..LVVPSSLH..EE--HHHH..xbbpaaaa
1nbf_A_4841nbf   A484493VVSRCTKEEAEEEE--HHHHbbbxbxaaaa
1ni4_B_1791ni4   B179187.PFEFPPEAQ.EEE--HHHH.xbxbxaaaa
1npb_A_681npb   A6877YAFTVAEEDFEEEE--HHHHbxbxbxaaaa
1o4s_A_2441o4s   A244253GYLISSEKVAEEEE--HHHHbbbbbxaaaa
1obd_A_1721obd   A172179..ENISPAQA..EE--HHHH..bxbxaaaa
1ojr_A_321ojr   A3342LTLRLDDADIEEEE--HHHHbbbxbbaaaa
1ooy_A_3341ooy   A337346GASYFSSDESEEEE--HHHHvxbbbxaaaa
1p3j_A_1921p3j   A195204VNGQQDIQDVEE-SS-HHHHbxaxbxaaaa
1poi_B_781poi   B7887CGCIWPNVRFEEEE--HHHHbabxxxaaaa
1q16_A_1571q16   A157165.FVRSSWQEV.EEE--HHHH.xbxbbaaaa
1r9l_A_421r9l   A4249..SEVDYNVG..EE--HHHH..xxbpaaaa
1rie_*_941rie   -97106FVRHRTKKEIEEEE--HHHHbbbxxxaaaa
1rif_A_121rif   A1322VRIDCEESTFEEEE--HHHHbbbbbxaaaa
1ry9_A_511ry9   A5766NFDAPSDVKLEEE---HHHHxxpxxxaaaa
1s4q_A_1161s4q   A116125VLIEVDLAGAEEEE--HHHHbbbbbxaaaa
1s96_A_981s96   A99108VFLDIDWQGAEEEE--HHHHbxbxbxaaaa
1scf_A_1071scf   A107115.PRLFTPEEF.EEE--HHHH.wbxbxaaaa
1spb_P_461spb   P4756ASATLNEKAVEEEE--HHHHbxbxbxaaaa
1uc2_A_261uc2   A2635GRVYADEVLLEEEE--HHHHbbbbbxaaaa
1ufa_A_3821ufa   A382389..RPVTAREA..EE--HHHH..bwbxaaaa
1v47_A_71v47   A715.ALEIGEDER.EEE--HHHH.bbxbxaaaa
1v7c_A_1261v7c   A128137VQVEGNFDDAEEESS-HHHHbbbxbxaaaa
1vjl_A_1391vjl   A139146..IELEVNER..EE--HHHH..bxxxaaaa
1vjl_A_291vjl   A3140LPIWIGACEGEEEE--HHHHbwbxbxaaaa
2nap_A_772nap   A7784..EPVSWDEA..EE--HHHH..bwbxaaaa
2nll_B_3172nll   B317324..CITCEGCK..EE--HHHH..bxbxaaaa
2uag_A_1532uag   A154163YVLELSSFQLEEEE--HHHHbbbxbxaaaa
3gcb_*_2973gcb   -298307IYLNVDNETLEEEE--HHHHbbbxbxaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ayf_A_561ayf   A     FESFE2/S2 (INORGANIC) CLUSTER H - 56
1bx4_A_161bx4   A     ADNADENOSINE L - 16
1bx4_A_161bx4   A     ADNADENOSINE L - 17
1bx4_A_161bx4   A     ADNADENOSINE D - 18
1bx4_A_161bx4   A     MO4MAGNESIUM ION, 4 WATERS COORDINATED L - 28
1bx4_A_161bx4   A     MO4MAGNESIUM ION, 4 WATERS COORDINATED D - 29
1bx4_A_161bx4   A     MO4MAGNESIUM ION, 4 WATERS COORDINATED K - 30
1dsz_A_11491dsz   A     ZNZINC ION A - 1151
1dsz_A_11491dsz   A     ZNZINC ION C - 1152
1dsz_A_11491dsz   A     ZNZINC ION E - 1153
1dsz_A_11491dsz   A     ZNZINC ION G - 1154
1dsz_A_11491dsz   A     ZNZINC ION C - 1155
1dsz_A_11491dsz   A     ZNZINC ION K - 1156
1dsz_B_12491dsz   B     ZNZINC ION S - 1251
1dsz_B_12491dsz   B     ZNZINC ION C - 1252
1dsz_B_12491dsz   B     ZNZINC ION E - 1253
1dsz_B_12491dsz   B     ZNZINC ION G - 1254
1dsz_B_12491dsz   B     ZNZINC ION C - 1255
1dsz_B_12491dsz   B     ZNZINC ION K - 1256
1dxy_*_1871dxy   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 191
1eu1_A_811eu1   A     CDCADMIUM ION D - 87
1eu1_A_811eu1   A     CDCADMIUM ION D - 91
1g8k_A_1311g8k   A     OC2CALCIUM ION, 2 WATERS COORDINATED V - 132
1gde_A_2431gde   A     PLPPYRIDOXAL-5'-PHOSPHATE G - 243
1gky_*_941gky   *     5GPGUANOSINE-5'-MONOPHOSPHATE D - 98
1gky_*_941gky   *     5GPGUANOSINE-5'-MONOPHOSPHATE I - 99
1gky_*_941gky   *     5GPGUANOSINE-5'-MONOPHOSPHATE D - 100
1gky_*_941gky   *     5GPGUANOSINE-5'-MONOPHOSPHATE Q - 102
1gky_*_941gky   *     5GPGUANOSINE-5'-MONOPHOSPHATE G - 103
1gky_*_941gky   *     5GPGUANOSINE-5'-MONOPHOSPHATE V - 104
1gs5_A_1561gs5   A     NLGN-ACETYL-L-GLUTAMATE N - 158
1gs5_A_1561gs5   A     NLGN-ACETYL-L-GLUTAMATE V - 159
1gs5_A_1561gs5   A     NLGN-ACETYL-L-GLUTAMATE N - 160
1gs5_A_1561gs5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER N - 160
1gs5_A_1561gs5   A     MGMAGNESIUM ION N - 160
1gs5_A_1561gs5   A     NLGN-ACETYL-L-GLUTAMATE A - 161
1gs5_A_1561gs5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER A - 161
1gs5_A_1561gs5   A     MGMAGNESIUM ION A - 161
1gs5_A_1561gs5   A     NLGN-ACETYL-L-GLUTAMATE D - 162
1gs5_A_1561gs5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER D - 162
1gs5_A_1561gs5   A     MGMAGNESIUM ION D - 162
1hsk_A_2071hsk   A     FADFLAVIN-ADENINE DINUCLEOTIDE R - 225
1i7p_A_2681i7p   A     FADFLAVIN-ADENINE DINUCLEOTIDE C - 273
1ile_*_1861ile   *     ZNZINC ION L - 188
1jdp_A_2121jdp   A     NAGN-ACETYL-D-GLUCOSAMINE S - 219
1jmx_A_1121jmx   A     HECHEME C Q - 112
1jmx_A_1121jmx   A     HECHEME C R - 114
1jmx_A_1121jmx   A     HECHEME C E - 118
1jmx_A_1121jmx   A     HECHEME C W - 119
1jmx_A_1121jmx   A     HECHEME C H - 121
1jmx_A_1121jmx   A     HECHEME C L - 122
1jmx_A_1121jmx   A     HECHEME C V - 123
1jmx_A_1121jmx   A     HECHEME C F - 125
1jmx_A_1121jmx   A     HECHEME C H - 126
1k4t_A_5361k4t   A     PG4TETRAETHYLENE GLYCOL R - 536
1lvg_A_971lvg   A     ADPADENOSINE-5'-DIPHOSPHATE D - 101
1lvg_A_971lvg   A     5GPGUANOSINE-5'-MONOPHOSPHATE D - 101
1lvg_A_971lvg   A     5GPGUANOSINE-5'-MONOPHOSPHATE V - 102
1lvg_A_971lvg   A     5GPGUANOSINE-5'-MONOPHOSPHATE D - 103
1lvg_A_971lvg   A     5GPGUANOSINE-5'-MONOPHOSPHATE L - 104
1lvg_A_971lvg   A     5GPGUANOSINE-5'-MONOPHOSPHATE Q - 105
1lvg_A_971lvg   A     5GPGUANOSINE-5'-MONOPHOSPHATE G - 106
1lvg_A_971lvg   A     5GPGUANOSINE-5'-MONOPHOSPHATE V - 107
1m2k_A_2231m2k   A     APRADENOSINE-5-DIPHOSPHORIBOSE G - 227
1m2k_A_2231m2k   A     APRADENOSINE-5-DIPHOSPHORIBOSE K - 228
1m2k_A_2231m2k   A     APRADENOSINE-5-DIPHOSPHORIBOSE A - 229
1m2k_A_2231m2k   A     APRADENOSINE-5-DIPHOSPHORIBOSE G - 230
1ni4_B_1791ni4   B     MSESELENOMETHIONINE P - 179
1ni4_B_1791ni4   B     MSESELENOMETHIONINE F - 180
1o4s_A_2441o4s   A     PLPPYRIDOXAL-5'-PHOSPHATE G - 244
1ojr_A_321ojr   A     ZNZINC ION N - 32
1ojr_A_321ojr   A     PO4PHOSPHATE ION N - 32
1ojr_A_321ojr   A     2HADIHYDROXYACETONE N - 32
1p3j_A_1921p3j   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 197
1p3j_A_1921p3j   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 198
1p3j_A_1921p3j   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 199
1p3j_A_1921p3j   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE D - 200
1p3j_A_1921p3j   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE I - 201
1p3j_A_1921p3j   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE V - 204
1r9l_A_421r9l   A     BETTRIMETHYL GLYCINE Y - 46
1s96_A_981s96   A     UNXUNKNOWN ATOM OR ION D - 102
1s96_A_981s96   A     MSESELENOMETHIONINE Q - 110
1s96_A_981s96   A     MSESELENOMETHIONINE I - 111
1s96_A_981s96   A     MSESELENOMETHIONINE R - 112
1s96_A_981s96   A     MSESELENOMETHIONINE Q - 113
1scf_A_1071scf   A     MSESELENOMETHIONINE L - 109
1scf_A_1071scf   A     CACALCIUM ION L - 109
1scf_A_1071scf   A     MSESELENOMETHIONINE F - 110
1scf_A_1071scf   A     CACALCIUM ION F - 110
1scf_A_1071scf   A     MSESELENOMETHIONINE T - 111
1scf_A_1071scf   A     CACALCIUM ION T - 111
1scf_A_1071scf   A     MSESELENOMETHIONINE P - 112
1scf_A_1071scf   A     CACALCIUM ION P - 112
1scf_A_1071scf   A     MSESELENOMETHIONINE E - 114
1scf_A_1071scf   A     MSESELENOMETHIONINE I - 118
1scf_A_1071scf   A     MSESELENOMETHIONINE R - 121
1scf_A_1071scf   A     CACALCIUM ION R - 121
1scf_A_1071scf   A     MSESELENOMETHIONINE S - 122
1scf_A_1071scf   A     CACALCIUM ION S - 122
1ufa_A_3821ufa   A     MSESELENOMETHIONINE R - 382
1v7c_A_1261v7c   A     HEY(2E)-2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL] PYRIDIN-4-YL}METHYL)AMINO]-5-PHOSPHONOPENT-2-ENOIC ACID F - 134
1v7c_A_1261v7c   A     HEY(2E)-2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL] PYRIDIN-4-YL}METHYL)AMINO]-5-PHOSPHONOPENT-2-ENOIC ACID L - 138
1vjl_A_291vjl   A     MSESELENOMETHIONINE A - 42
1vjl_A_291vjl   A     MSESELENOMETHIONINE L - 43
1vjl_A_291vjl   A     MSESELENOMETHIONINE A - 44
1vjl_A_291vjl   A     MSESELENOMETHIONINE L - 45
2nll_B_3172nll   B     ZNZINC ION T - 319
2nll_B_3172nll   B     ZNZINC ION C - 320
2nll_B_3172nll   B     ZNZINC ION E - 321
2nll_B_3172nll   B     ZNZINC ION G - 322
2nll_B_3172nll   B     ZNZINC ION C - 323
2nll_B_3172nll   B     ZNZINC ION K - 324
2uag_A_1532uag   A     MGMAGNESIUM ION E - 157
2uag_A_1532uag   A     UMAURIDINE-5'-DIPHOSPHATE-N-ACETYLMURAMOYL-L-ALANINE E - 157
2uag_A_1532uag   A     ADPADENOSINE-5'-DIPHOSPHATE E - 157
2uag_A_1532uag   A     KCXLYSINE NZ-CARBOXYLIC ACID L - 158
2uag_A_1532uag   A     KCXLYSINE NZ-CARBOXYLIC ACID S - 159
2uag_A_1532uag   A     MGMAGNESIUM ION S - 159
2uag_A_1532uag   A     UMAURIDINE-5'-DIPHOSPHATE-N-ACETYLMURAMOYL-L-ALANINE S - 159
2uag_A_1532uag   A     KCXLYSINE NZ-CARBOXYLIC ACID S - 160
2uag_A_1532uag   A     KCXLYSINE NZ-CARBOXYLIC ACID F - 161
2uag_A_1532uag   A     UMAURIDINE-5'-DIPHOSPHATE-N-ACETYLMURAMOYL-L-ALANINE F - 161
2uag_A_1532uag   A     UMAURIDINE-5'-DIPHOSPHATE-N-ACETYLMURAMOYL-L-ALANINE Q - 162
2uag_A_1532uag   A     KCXLYSINE NZ-CARBOXYLIC ACID L - 163
3gcb_*_2973gcb   *     GOLGLYCEROL R - 314
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1an8_*_501an8   * ZNBTHIS SITE ALSO INCLUDES HIS 35 AND GLU 54 FROM A SYMMETRY-RELATED MOLECULE.E - 54
1gs5_A_1561gs5   A NLGNLG BINDING SITE FOR CHAIN AA - 161
1ojr_A_321ojr   A POAPO4 A1276 BINDING SITEN - 32

Clusters included in this Subclass
CLUSTER: EH.1.9
CLUSTER: EH.2.13
CLUSTER: EH.2.36
CLUSTER: EH.3.9
CLUSTER: EH.4.158