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Information on SUBCLASS 1.1.8
Subclass Accession number: 2637
Subclass: 1.1.8 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 59

Average sequence ID (%) : 8.4 +/- 12.2
Average RMSD (Å) : 0.454 +/- 0.180

Consensus geometry
d (Å): 7 delta (°): 0-45 theta (°): 90-135 rho (°): 180-225
Consensus Sequence: XhXXp
(φψ)-conformation: bbpaa
Pattern: xxx[acfgilmpvy][degnpqst]x[adegknrst]xx
Conservation:-1.000-0.729-0.8871.1530.812-1.2331.383-0.5080.009
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
16pk_*_18816pk   -188194..AAGYLME..EE-HHHH..bxxaaaa
1aui_B_361aui   B3642..SLSVEEF..EE-HHHH..bxbaaaa
1b8z_A_781b8z   A7886KFKPGKALKEEEE-HHHHbbbxxaaaa
1be4_A_341be4   A4048FMRASEDLLEEE--HHHHbbxxxaaaa
1beb_A_1471beb   A148156RLSFNPTQLEEE--HHHHbbbbxaaaa
1bqy_A_1561bqy   A160168INILDHAVCEEEE-HHHHbbxbxaaaa
1ddj_A_6981ddj   A702710LPVIENKVCEEEE-HHHHbxxbpaaaa
1ejd_A_811ejd   A8187..SAPYDLV..EE-HHHH..bxxaaaa
1elv_A_5681elv   A572580LPVAPLRKCEEEE-HHHHbxxbwaaaa
1ep5_A_1751ep5   A177185YADVPQNMREEE--HHHHbbxxwaaaa
1eq9_A_1561eq9   A160168LIVHPQKQCEEEE-HHHHbbxxpaaaa
1ex0_A_5811ex0   A586594AVLIQAGEYEEEE-HHHHbbxxxaaaa
1fp2_A_921fp2   A93101SYALTVASEEEEE-HHHHbbbxbaaaa
1gdn_A_1561gdn   A160168VPIVSRATCEEEE-HHHHbxxbpaaaa
1gj7_B_1561gj7   B160168VKLISHRECEEEE-HHHHbbxbxaaaa
1gs4_A_7681gs4   A768775.LVFNEYRM.EEE-HHHH.bxxbaaaa
1h0c_A_2181h0c   A219227LISFSDKAKEEEE-HHHHbbbbxaaaa
1hhs_A_2261hhs   A226233.MVADFEYA.EEE-HHHH.xbxxaaaa
1htr_B_2671htr   B268276EFPLPPSSYEEEE-HHHHxbxbxaaaa
1i40_A_1501i40   A153161EGWENAEAAEEEE-HHHHaexbxaaaa
1ii5_A_681ii5   A7280PISVTPERAEEE--HHHHwxxxbaaaa
1iq8_A_4891iq8   A489496.LTLGIEGA.EEE-HHHH.xxxbaaaa
1jdr_A_1791jdr   A179185..KTHLKNS..EE-HHHH..bxbaaaa
1jh6_A_431jh6   A4856SAYLTADEAEEEE-HHHHxxxbxaaaa
1jhs_A_1681jhs   A175183NVPLTKEEAEEE--HHHHxbxxxaaaa
1k8k_D_2201k8k   D224232TFVLFPRHTEEEE-HHHHbbbbbaaaa
1kic_A_2051kic   A205213RIMFSLDSTEEEE-HHHHbbbxxaaaa
1kzl_A_1571kzl   A158166SIMMISYTQEEEE-HHHHbbbxxaaaa
1mvl_A_991mvl   A102110IAPLSANTLEEEE-HHHHbbwbxaaaa
1n97_A_21n97   A29.KRLSLREA.EE--HHHH.xbxxaaaa
1na6_A_181na6   A2230IKRLSANDTEEE--HHHHbbxxxaaaa
1nh0_A_841nh0   A8490..IIGRNLL..EE-HHHH..bxxaaaa
1npy_A_761npy   A7682..EIHPSAQ..EE-HHHH..bxxaaaa
1o4y_A_2221o4y   A224232VRTVTRAEIEEEE-HHHHabbbbaaaa
1oi2_A_3381oi2   A344352LLKVDDETLEEEE-HHHHbbxbbaaaa
1on2_A_591on2   A5967GLVLTSKGKEEEE-HHHHexbxxaaaa
1os8_A_1561os8   A160168VPFVSDAACEEEE-HHHHbwxbxaaaa
1p57_B_1561p57   B160168VPIISNDVCEEEE-HHHHbxxbxaaaa
1p9r_A_4021p9r   A403411PYEADKEQREEE--HHHHwbbpxaaaa
1pn0_A_551pn0   A5561..GLQCRTL..EE-HHHH..bbxaaaa
1pso_E_2651pso   E266274QYPVPPSAYEEEE-HHHHxbwbxaaaa
1q8f_A_1841q8f   A184192LVMMGLDLTEEEE-HHHHbbbxxaaaa
1qdm_A_2731qdm   A274282KFALKPEEYEEEE-HHHHbxxbxaaaa
1qus_A_3231qus   A325333YWYGLPNFYEEEE-HHHHxbxxbaaaa
1rkg_A_2901rkg   A290296..KYDVTDV..EE-HHHH..bbbaaaa
1sbp_*_2791sbp   -279286.KLFTIDEV.EEE-HHHH.xbbbaaaa
1sdo_A_1561sdo   A159167EILPMKELSEEEE-HHHHbbbxxaaaa
1smr_A_2651smr   A266274AYTLSSTDYEEEE-HHHHxbbbxaaaa
1ual_A_831ual   A9199GRKLDQGGVEEE--HHHHxxxxbaaaa
1uch_*_491uch   -5563LFPITEKYEEEE--HHHHxbxxbaaaa
1ukm_A_141ukm   A2028GEPQNWYEAEEEE-HHHHaxwbxaaaa
1ur1_A_361ur1   A3846GAALNATIAEEEE-HHHHbbxbxaaaa
1uv0_A_241uv0   A3038LSPKSWTDAEEEE-HHHHaxwbxaaaa
1vhv_A_541vhv   A5461.VELERSDL.EEE-HHHH.xxbbaaaa
1vhy_A_171vhy   A1725QCYLSEDAAEEE--HHHHbbxxxaaaa
1wdn_A_641wdn   A6876GITITDERKEEE--HHHHlxpxbaaaa
2eng_*_1812eng   -186194QVQCPAELVEE---HHHHxbxxxaaaa
2hlc_A_1562hlc   A160168NLVIDNDRCEEEE-HHHHbxxbxaaaa
2prd_*_1502prd   -153161TGWRDRKAAEEEE-HHHHaebbxaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1aui_B_361aui   B     CACALCIUM ION S - 36
1aui_B_361aui   B     CACALCIUM ION L - 37
1aui_B_361aui   B     CACALCIUM ION S - 38
1aui_B_361aui   B     CACALCIUM ION E - 41
1be4_A_341be4   A     PCGCYCLIC GUANOSINE MONOPHOSPHATE H - 51
1be4_A_341be4   A     PCGCYCLIC GUANOSINE MONOPHOSPHATE Y - 52
1ejd_A_811ejd   A     HAICYCLOHEXYLAMMONIUM ION S - 81
1ep5_A_1751ep5   A     UREUREA L - 175
1ep5_A_1751ep5   A     UREUREA Y - 177
1gdn_A_1561gdn   A     GOLGLYCEROL K - 157
1gdn_A_1561gdn   A     GOLGLYCEROL I - 162
1gdn_A_1561gdn   A     GOLGLYCEROL V - 163
1gdn_A_1561gdn   A     GOLGLYCEROL S - 164
1gdn_A_1561gdn   A     GOLGLYCEROL R - 165
1gdn_A_1561gdn   A     GOLGLYCEROL A - 166
1gj7_B_1561gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE V - 160
1gs4_A_7681gs4   A     PO4PHOSPHATE ION K - 777
1i40_A_1501i40   A     CACALCIUM ION V - 150
1i40_A_1501i40   A     CACALCIUM ION K - 151
1i40_A_1501i40   A     CACALCIUM ION V - 152
1ii5_A_681ii5   A     GLUGLUTAMIC ACID P - 72
1ii5_A_681ii5   A     GLUGLUTAMIC ACID I - 73
1ii5_A_681ii5   A     GLUGLUTAMIC ACID S - 74
1ii5_A_681ii5   A     GLUGLUTAMIC ACID V - 75
1ii5_A_681ii5   A     GLUGLUTAMIC ACID R - 79
1jdr_A_1791jdr   A     HEMPROTOPORPHYRIN IX CONTAINING FE K - 179
1jdr_A_1791jdr   A     HEMPROTOPORPHYRIN IX CONTAINING FE T - 180
1jdr_A_1791jdr   A     HEMPROTOPORPHYRIN IX CONTAINING FE H - 181
1jdr_A_1791jdr   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 182
1jdr_A_1791jdr   A     HEMPROTOPORPHYRIN IX CONTAINING FE K - 183
1jdr_A_1791jdr   A     HEMPROTOPORPHYRIN IX CONTAINING FE N - 184
1jdr_A_1791jdr   A     HEMPROTOPORPHYRIN IX CONTAINING FE S - 185
1kic_A_2051kic   A     NOSINOSINE L - 210
1kzl_A_1571kzl   A     CRM3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID I - 159
1kzl_A_1571kzl   A     CRM3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID M - 160
1kzl_A_1571kzl   A     CRM3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID M - 161
1kzl_A_1571kzl   A     CRM3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID I - 162
1kzl_A_1571kzl   A     CRM3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID S - 163
1kzl_A_1571kzl   A     CRM3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID Y - 164
1kzl_A_1571kzl   A     CRM3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID T - 165
1kzl_A_1571kzl   A     CRM3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID Q - 166
1mvl_A_991mvl   A     FMNFLAVIN MONONUCLEOTIDE L - 105
1mvl_A_991mvl   A     FMNFLAVIN MONONUCLEOTIDE S - 106
1mvl_A_991mvl   A     FMNFLAVIN MONONUCLEOTIDE A - 107
1mvl_A_991mvl   A     FMNFLAVIN MONONUCLEOTIDE N - 108
1mvl_A_991mvl   A     FMNFLAVIN MONONUCLEOTIDE T - 109
1mvl_A_991mvl   A     FMNFLAVIN MONONUCLEOTIDE L - 110
1mvl_A_991mvl   A     FMNFLAVIN MONONUCLEOTIDE K - 112
1n97_A_21n97   A     EGLETHYLENE GLYCOL L - 13
1n97_A_21n97   A     EGLETHYLENE GLYCOL Q - 17
1nh0_A_841nh0   A     KI23-BENZYLOXYCARBONYLAMINO-2-HYDROXY-4-PHENYL-BUTYRIC ACID I - 84
1on2_A_591on2   A     MNMANGANESE (II) ION L - 73
1on2_A_591on2   A     MNMANGANESE (II) ION H - 77
1os8_A_1561os8   A     CACALCIUM ION D - 165
1pn0_A_551pn0   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 55
1pn0_A_551pn0   A     IPHPHENOL G - 55
1pn0_A_551pn0   A     IPHPHENOL L - 56
1q8f_A_1841q8f   A     GOLGLYCEROL L - 189
1rkg_A_2901rkg   A     VD15-{2-[1-(1-METHYL-PROPYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-2-METHYLENE-CYCLOHEXANE-1,3-DIOL Y - 291
1rkg_A_2901rkg   A     VD15-{2-[1-(1-METHYL-PROPYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-2-METHYLENE-CYCLOHEXANE-1,3-DIOL V - 296
1ual_A_831ual   A     SAHS-ADENOSYL-L-HOMOCYSTEINE Y - 86
1ual_A_831ual   A     SAHS-ADENOSYL-L-HOMOCYSTEINE L - 87
1ual_A_831ual   A     SAHS-ADENOSYL-L-HOMOCYSTEINE S - 88
1ual_A_831ual   A     SAHS-ADENOSYL-L-HOMOCYSTEINE P - 89
1ual_A_831ual   A     SAHS-ADENOSYL-L-HOMOCYSTEINE Q - 90
1ur1_A_361ur1   A     AHRALPHA-L-ARABINOFURANOSE N - 42
1uv0_A_241uv0   A     ZNZINC ION H - 24
1uv0_A_241uv0   A     ZNZINC ION W - 35
1vhy_A_171vhy   A     MSESELENOMETHIONINE H - 27
1vhy_A_171vhy   A     MSESELENOMETHIONINE V - 28
1vhy_A_171vhy   A     MSESELENOMETHIONINE A - 29
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1aui_B_361aui   B CA1CALCIUM BINDING SITE.S - 36
1aui_B_361aui   B CA1CALCIUM BINDING SITE.E - 41
1be4_A_341be4   A NULC-GMP BINDING SITE.Y - 52
1gs4_A_7681gs4   A AC2PO4 BINDING SITE FOR CHAIN AK - 777
1h0c_A_2181h0c   A AC5GOL BINDING SITE FOR CHAIN AK - 228
1ur1_A_361ur1   A AC4CL BINDING SITE FOR CHAIN AA - 43
1uv0_A_241uv0   A AC2ZN BINDING SITE FOR CHAIN AH - 24

Clusters included in this Subclass
CLUSTER: EH.0.12
CLUSTER: EH.0.26
CLUSTER: EH.1.144
CLUSTER: EH.1.165
CLUSTER: EH.1.23
CLUSTER: EH.1.42
CLUSTER: EH.2.18
CLUSTER: EH.2.187
CLUSTER: EH.2.194
CLUSTER: EH.2.225
CLUSTER: EH.3.81