ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 1.1.12

Subclass Accession number: 2641
Subclass: 1.1.12

Type: EH beta-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Number of loops: 35

Average sequence ID (%) : 10.9 +/- 14.9
Average RMSD (Å) : 0.566 +/- 0.181

Consensus geometry

d (Å): 9

delta (°): 45-90

theta (°): 90-135

rho (°): 135-180

Consensus Sequence:	XhpXp
(φψ)-conformation:	bbpaa

Pattern:	x	x	[filtvy]	[deknpqrst]	x	[adekrst]	[adenqrst]	x	x	x	x
Conservation:	0.504	-1.363	1.295	0.512	-0.829	1.040	1.432	-1.120	-0.807	-0.345	-0.319

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1aye_*_52	1aye	-	54	64	VRVPFVNVQAV	EEE-GGGHHHH	bxbwaaaaaaa
1b24_A_160	1b24	A	163	173	LNISLRDRIKF	EEE-GGGHHHH	bbxpaaaaaaa
1dug_A_28	1dug	A	30	40	HLYERDEGDKW	EEE-TT-HHHH	bxxxaaaaaaa
1eo9_A_139	1eo9	A	142	152	RVYFDDEAEAN	EEEEGGGHHHH	bbbbaaaaaaa
1f4p_A_66	1f4p	A	66	75	.ELQDDFIPLF	.EE-TTTHHHH	.bxpaaaaaaa
1fi4_A_307	1fi4	A	309	319	LYYLAENESKL	EEE-GGGHHHH	bxbxaaaaaaa
1gne_*_28	1gne	-	30	40	HLYERDEGDKW	EEE-TTTHHHH	bbxbaaaaaaa
1gx5_A_450	1gx5	A	452	462	YSIEPLDLPQI	EEE-GGGHHHH	xbbxaaaaaaa
1gyx_A_40	1gyx	A	44	54	QQIQPESWQAI	EE--GGGHHHH	bxbxaaaaaaa
1h2k_A_214	1h2k	A	217	227	ILFPPDQFECL	EEE-GGGHHHH	bbbxaaaaaaa
1inl_A_65	1inl	A	66	76	TMTTEKDEFMY	EEEETTTHHHH	xabbaaaaaaa
1iq8_A_509	1iq8	A	510	520	VVVNKEAEPFA	EEE-TTTHHHH	bxbxaaaaaaa
1iy9_A_51	1iy9	A	52	62	VMTSEKDEFVY	EEEETTTHHHH	xabbaaaaaaa
1iyh_A_30	1iyh	A	32	42	HRIEQADWPEI	EEE-GGGHHHH	xbxbaaaaaaa
1jj2_O_21	1jj2	O	21	31	VWFNPERQGDI	EEE-GGGHHHH	xbbpaaaaaaa
1jqn_A_608	1jqn	A	610	620	VTEQGEMIRFK	EEE-GGGHHHH	bxxxaaaaaaa
1kol_A_364	1kol	A	365	375	QVISLDDAPRG	EEE-GGGHHHH	bxbxaaaaaaa
1l5j_A_410	1l5j	A	411	421	VGSQDTTGPMT	EEE-TTTHHHH	bbbbaaaaaaa
1llu_A_314	1llu	A	315	325	HPGKLDDINQI	EEE-GGGHHHH	bwbbaaaaaaa
1m0u_A_76	1m0u	A	78	88	VRVTRDEWPAL	EEE-TTTHHHH	xbxxaaaaaaa
1m44_A_113	1m44	A	116	126	LSSSARARRLY	EE--TTTHHHH	bbbxaaaaaaa
1nth_A_134	1nth	A	134	143	.PISEDVFMPV	.EE-GGGHHHH	.wbxaaaaaaa
1o59_A_3	1o59	A	3	12	.FFSLADEAEF	.EE-GGGHHHH	.bbpaaaaaaa
1o89_A_296	1o89	A	296	306	KEISLSEAPNF	EEE-GGGHHHH	xxbxaaaaaaa
1ovn_A_28	1ovn	A	28	38	VDLDELSFEKT	EEE-TTTHHHH	bxbbaaaaaaa
1pca_*_52	1pca	-	54	64	VRVPFPSIQAV	EEE-GGGHHHH	bxbxaaaaaaa
1pd2_1_30	1pd2	1	32	42	HRIEQADWPKI	EEE-TTTHHHH	xbbxaaaaaaa
1pjr_*_189	1pjr	-	189	198	.SLDFDDLIMT	.EE-TTHHHHH	.bbxaaaaaaa
1t7p_A_30	1t7p	A	32	42	VSYRPSDFGAY	EEE-GGGHHHH	bxbxaaaaaaa
1uir_A_52	1uir	A	53	63	VQSTERDEYIY	EEEETTTHHHH	xabbaaaaaaa
1uoc_A_17	1uoc	A	17	27	RDVWKSNLYSE	EEE-TTTHHHH	xxbbaaaaaaa
1uuf_A_316	1uuf	A	317	327	EMIRADQINEA	EEE-GGGHHHH	bxbxaaaaaaa
2fhe_A_27	2fhe	A	30	40	QIYERDDGEKW	EEE-TT-HHHH	xxbxaaaaaaa
2pva_A_98	2pva	A	98	108	TGINPVYVISQ	EEE-GGGHHHH	bxbxaaaaaaa
3pcc_A_139	3pcc	A	142	152	RLYFDDEAQAN	EEEETT-HHHH	bbbbaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1dug_A_28	1dug	A	GSHGLUTHATHIONE	W - 40
1dug_A_28	1dug	A	GSHGLUTHATHIONE	R - 41
1f4p_A_66	1f4p	A	FMNFLAVIN MONONUCLEOTIDE	Q - 68
1fi4_A_307	1fi4	A	MSESELENOMETHIONINE	Y - 310
1fi4_A_307	1fi4	A	MSESELENOMETHIONINE	Y - 311
1fi4_A_307	1fi4	A	MSESELENOMETHIONINE	L - 312
1fi4_A_307	1fi4	A	MSESELENOMETHIONINE	A - 313
1gx5_A_450	1gx5	A	MSESELENOMETHIONINE	I - 463
1gx5_A_450	1gx5	A	MSESELENOMETHIONINE	L - 466
1gx5_A_450	1gx5	A	MSESELENOMETHIONINE	H - 467
1gyx_A_40	1gyx	A	BEZBENZOIC ACID	W - 51
1h2k_A_214	1h2k	A	OGAN-OXALYOLGLYCINE	K - 214
1iyh_A_30	1iyh	A	GSHGLUTHATHIONE	W - 39
1iyh_A_30	1iyh	A	GSHGLUTHATHIONE	K - 43
1jqn_A_608	1jqn	A	DCO3,3-DICHLORO-2-PHOSPHONOMETHYL-ACRYLIC ACID	T - 611
1jqn_A_608	1jqn	A	ASPASPARTIC ACID	M - 616
1kol_A_364	1kol	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	F - 379
1l5j_A_410	1l5j	A	TRAACONITATE ION	Q - 414
1l5j_A_410	1l5j	A	TRAACONITATE ION	D - 415
1l5j_A_410	1l5j	A	TRAACONITATE ION	T - 416
1l5j_A_410	1l5j	A	TRAACONITATE ION	T - 417
1llu_A_314	1llu	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	M - 329
1llu_A_314	1llu	A	EDO1,2-ETHANEDIOL	R - 330
1m0u_A_76	1m0u	A	GTTGLUTATHIONE	W - 85
1o59_A_3	1o59	A	MSESELENOMETHIONINE	F - 3
1pca_*_52	1pca	*	CITCITRIC ACID	L - 68
1pca_*_52	1pca	*	CITCITRIC ACID	A - 70
1pd2_1_30	1pd2	1	GTTGLUTATHIONE	W - 39
1uoc_A_17	1uoc	A	CACALCIUM ION	R - 32
1uoc_A_17	1uoc	A	CACALCIUM ION	Q - 33
1uoc_A_17	1uoc	A	CACALCIUM ION	L - 34
2pva_A_98	2pva	A	DTDDITHIANE DIOL	V - 103

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1gyx_A_40	1gyx	A	AC2BEZ BINDING SITE FOR CHAIN A	W - 51
1uoc_A_17	1uoc	A	AC1ENVIRONMENT FOR CA IN CHAIN A	Q - 33

Clusters included in this Subclass