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| Information on SUBCLASS 1.1.22 |
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Subclass Accession number: 2651
Subclass: 1.1.22 
Type: EH beta-alpha DB: ArchDB95 Image coordinates: 
 Consensus coordinates:
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Number of loops: 12 Average sequence ID (%) : 10.9 +/- 14.5 Average RMSD (Å) : 0.583 +/- 0.147 Consensus geometry
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| Consensus Sequence: | XhpXp |
| (φψ)-conformation: | bbpaa |
| Pattern: | x | x | [fiv] | [EHKNPRST] | x | [aekqrt] | [dnrsty] | x | [agimpv] | x | [afilmt] |
| Conservation: | -0.565 | -1.388 | 2.493 | 0.428 | -0.508 | 0.699 | -0.144 | -0.218 | -0.556 | -0.438 | 0.197 |
| Loops included in this Subclass |
| Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
| 1a26_*_857 | 1a26 | - | 862 | 872 | HGSRTTNFAGI | EE--GGGHHHH | bbbxaaaaaaa |
| 1a3q_A_136 | 1a3q | A | 139 | 149 | LHVTKKNMMGT | EE--TTTHHHH | xxxxaaaaaaa |
| 1b24_A_160 | 1b24 | A | 163 | 173 | LNISLRDRIKF | EEE-GGGHHHH | bbxpaaaaaaa |
| 1e4y_A_105 | 1e4y | A | 109 | 119 | FDVPDELIVDR | EE--TTHHHHH | bbbxaaaaaaa |
| 1ikn_A_117 | 1ikn | A | 119 | 129 | QCVKKRDLEQA | EE--GGGHHHH | xxbxaaaaaaa |
| 1jj2_O_21 | 1jj2 | O | 21 | 31 | VWFNPERQGDI | EEE-GGGHHHH | xbbpaaaaaaa |
| 1oe8_A_32 | 1oe8 | A | 34 | 44 | ERISFQDWPKI | EE--TTTHHHH | bxxxaaaaaaa |
| 1r3e_A_240 | 1r3e | A | 241 | 251 | VVVHQESTKMI | EE--TTTHHHH | bbbxaaaaaaa |
| 1set_A_402 | 1set | A | 402 | 412 | VRVPQALIPYM | EE--GGGHHHH | bxbwaaaaaaa |
| 2gsq_*_29 | 2gsq | - | 31 | 41 | RVVEMADWPNL | EE--TTTHHHH | xxbxaaaaaaa |
| 2gsr_A_29 | 2gsr | A | 31 | 41 | EVVTMETWPPL | EE--TTTHHHH | bxbbaaaaaaa |
| 2pva_A_98 | 2pva | A | 98 | 108 | TGINPVYVISQ | EEE-GGGHHHH | bxbxaaaaaaa |
| PDB ligands within a cut-off distance of 6 Å in this subclass |
| Loop | PDB | Chain | Ligands | Residue |
| 1e4y_A_105 | 1e4y | A | AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE | F - 109 |
| 1e4y_A_105 | 1e4y | A | AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE | R - 119 |
| 1e4y_A_105 | 1e4y | A | AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE | I - 120 |
| 1oe8_A_32 | 1oe8 | A | GSHGLUTHATHIONE | W - 41 |
| 2gsq_*_29 | 2gsq | * | GBIS-(3-IODOBENZYL)GLUTATHIONE | M - 35 |
| 2gsq_*_29 | 2gsq | * | GBIS-(3-IODOBENZYL)GLUTATHIONE | W - 38 |
| 2gsr_A_29 | 2gsr | A | OCSCYSTEINESULFONIC ACID | W - 38 |
| 2pva_A_98 | 2pva | A | DTDDITHIANE DIOL | V - 103 |
| PDB Site Annotated loops in this subclass |
| Loop | PDB | Chain | Site | Residue |
| 1e4y_A_105 | 1e4y | A | AC1AP5 BINDING SITE FOR CHAIN A | R - 119 |
| 1oe8_A_32 | 1oe8 | A | AC1GSH BINDING SITE FOR CHAIN A | W - 41 |
| Clusters included in this Subclass |
| CLUSTER: EH.4.46 |
| CLUSTER: EH.5.39 |
| CLUSTER: EH.6.99 |
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