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Information on SUBCLASS 1.2.2
Subclass Accession number: 2700
Subclass: 1.2.2 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 63

Average sequence ID (%) : 10.8 +/- 13.8
Average RMSD (Å) : 0.397 +/- 0.188

Consensus geometry
d (Å): 9 delta (°): 45-90 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: XXXXp
(φψ)-conformation: bpaaa
Pattern: x[acfgilmvy]xxxxx[afiklmtv][adegnpqst]x[afgilmvy]
Conservation:1.9600.222-0.363-0.348-1.091-0.889-0.8891.021-0.092-0.7471.216
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1amu_A_1391amu   A140150LLTQKHLVHLIEEE-GGGHHHHbxbbaaaaaaa
1atg_*_31atg   -515VVTATNFLGTLEEEEGGGHHHHbbbpaaaaaaa
1atz_A_10861atz   A10871097KLQRIEDLPTMEESSTTHHHHHbbabaaaaaaa
1azc_A_491azc   A4959VLTKEADKQGVEEEEGGGHHHHbbbxaaaaaaa
1b65_A_1031b65   A104114VITNTHGIGMAEEEEGGGHHHHbbbxaaaaaaa
1b93_A_131b93   A1626LVAHDHCKQMLEEE-GGGHHHHbbbxaaaaaaa
1bfd_*_3711bfd   -373383LNESTSTTAQMEEE-GGGHHHHbbabaaaaaaa
1cb6_A_15981cb6   A15991609VVSRMDKVERLEEE-GGGHHHHxbbxaaaaaaa
1chd_*_3261chd   -326336EVVDLSQVSQQEEE-GGGHHHHbbbxaaaaaaa
1cjw_A_1551cjw   A158168LMCEDALVPFYEEE-GGGHHHHbbbxaaaaaaa
1cli_A_3021cli   A306316IALPAPEVDKAEEE-GGGHHHHbbbwaaNaaaa
1cuo_A_491cuo   A4959VLAKSADVGDVEEEEGGGHHHHbbbxaaaaaaa
1dms_*_3961dms   -396405.VIPVARVVDM.EEEGGGHHHH.bbxaaaaaaa
1dyz_A_491dyz   A4959VLTKDADKQAVEEEEGGGHHHHbbbxaaaaaaa
1eke_A_201eke   A2333FAIEKEREEELEEE-GGGHHHHbbbxaaaaaaa
1elj_A_2241elj   A225235MVNGPWSINDVEEE-GGGHHHHbxbbaaaaaaa
1eu1_A_3961eu1   A396405.SIPCARVVDM.EEEGGGHHHH.bbpaaaaaaa
1ey3_A_2111ey3   A211221KIFPVETLVEEEEE-TTTHHHHbbbwaaaaaaa
1fi4_A_3071fi4   A309319LYYLAENESKLEEE-GGGHHHHbxbxaaaaaaa
1fiu_A_2741fiu   A274283.LKDISDLPLD.EEEGGGHHHH.bbxaaaaaaa
1h5r_A_491h5r   A5464IISTPQDTPRFEEE-TTTHHHHbbbxaaaaaaa
1h72_C_2651h72   C267277AFPKEEFIDEVEEE-GGGHHHHbbxxaaaaaaa
1h76_A_5951h76   A596606VVARDDKVTCVEEE-GGGHHHHxbbxaaaaaaa
1hye_A_281hye   A3141LIGREHSINKLEEE-GGGHHHHbbbxaaaaaaa
1i19_A_4311i19   A437447VVTSRANIATVEEE-GGGHHHHbxbxaaaaaaa
1i2a_A_1041i2a   A105115FIAQADLMPLIEEEEGGGHHHHbbbpaaaaaaa
1iib_A_341iib   A3747EAFPETLAGEKEEEEGGGHHHHbbbxaaaaaaa
1iq7_A_5931iq7   A594604VVVRPEKANKIEEE-GGGHHHHxbbxaaaaaaa
1j5y_A_711j5y   A7787VKHAPEEIKEEEE--GGGHHHHbbbxaaaaaaa
1jv1_A_1621jv1   A164174IMTSGRTMESTEEE-TTTHHHHbxbbaaNaaaa
1k0r_A_2891k0r   A292302VVVPDFQLSLAEEE-GGGHHHHbbbpaaaaaaa
1kbl_A_8511kbl   A852862VSCSPFRVPIAEEE-GGGHHHHbbbxaaaaaaa
1kfu_L_6221kfu   L622630..MNSYEMRKA..EESTTHHHH..bxaaaaaaa
1kol_A_3641kol   A365375QVISLDDAPRGEEE-GGGHHHHbxbxaaaaaaa
1kon_A_1701kon   A172182VYTAWEEMGKVEEEEGGGHHHHbbbxaaaaaaa
1lbv_A_2361lbv   A237247VAANEKLHPKLEEE-TTTHHHHbbbxaaaaaaa
1lci_*_1251lci   -126136VFVSKKGLQKIEEE-GGGHHHHbxbxaaaaaaa
1lfp_A_1701lfp   A173183IYTVPEELYEVEEE-GGGHHHHbbbxaaaaaaa
1lk5_A_1361lk5   A138148IEVIPQAWKAIEEE-GGGHHHHbxbpaaaaaaa
1m0s_A_1321m0s   A134144VEVIPMARSQVEEE-GGGHHHHbxbpaaaaaaa
1m6j_A_401m6j   A4454VGVPFIYIPKVEEE-GGGHHHHbxbwaaaaaaa
1msw_D_8131msw   D814824FGTIPADAANLEEE-GGGHHHHbbbxaaaaaaa
1mzh_A_1361mzh   A137147VCVNPYHVKLAEEE-GGGHHHHbbbxaaaaaaa
1nbf_A_5111nbf   A517527VYIRESKLSEVEEEEGGGHHHHbbbxaaaaaaa
1nh8_A_431nh8   A4656FFLRPKDIAIYEEE-GGGHHHHbbbpaaaaaaa
1nkx_A_5961nkx   A597607VVSRSDRAAHVEEEEGGGHHHHxbbxaaaaaaa
1nml_A_951nml   A95104.DGRAADLAEQ.EEEGGGHHHH.bbxaaaaaaa
1nw2_A_31nw2   A313MTLTDANFQQAEEE-TTTHHHHxxbbaaaaaaa
1nwp_A_491nwp   A4959VISKEADMQPIEEEEGGGHHHHbbbpaaaaaaa
1o0y_A_631o0y   A6474VCVNPCYVKLAEEE-GGGHHHHbbbxaaaaaaa
1otg_A_31otg   A616VECSDNIREEAEEEEGGGHHHHbbbxaaaaaaa
1qy7_A_21qy7   A616AIIRPFKLDEVEEE-GGGHHHHbbbxaaaaaaa
1r94_A_601r94   A6272VVVDGKSLQFLEEEEGGGHHHHbbbpaaaaaaa
1rkr_A_491rkr   A4959VLTKQADMQGAEEEEGGGHHHHbbbxaaaaaaa
1sbp_*_21sbp   -717NVSYDPTRELYEEE-STTHHHHbxbxaaaaaaa
1tmo_*_4051tmo   -405414.TIPVARWIDA.EEEGGGHHHH.bbxaaaaaaa
1urs_A_2491urs   A250260YVSGPWDTADIEEE-GGGHHHHbxbbaaaaaaa
1uuf_A_3161uuf   A317327EMIRADQINEAEEE-GGGHHHHbxbxaaaaaaa
1vk3_A_2871vk3   A287297VVTSPQKASRIEEE-GGGHHHHbxbxaaaaaaa
2btm_A_362btm   A3949VCAPFLFLDRLEEE-GGGHHHHbbbwaaaaaaa
2pii_*_22pii   -616AIIKPFKLDDVEEE-GGGHHHHbbbxaaaaaaa
2por_*_402por   -4353ASFKAHESVGAEEEEGGGHHHHbbbxaaaaaaa
3mbp_*_2223mbp   -225235TINGPWAWSNIEEE-GGGHHHHbbbbaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1atg_*_31atg   *     EDO1,2-ETHANEDIOL V - 6
1atg_*_31atg   *     WO4TUNGSTATE(VI)ION A - 8
1atg_*_31atg   *     WO4TUNGSTATE(VI)ION T - 9
1atg_*_31atg   *     WO4TUNGSTATE(VI)ION N - 10
1atg_*_31atg   *     WO4TUNGSTATE(VI)ION F - 11
1atg_*_31atg   *     EDO1,2-ETHANEDIOL Q - 17
1b93_A_131b93   A     FMTFORMIC ACID L - 16
1b93_A_131b93   A     FMTFORMIC ACID V - 17
1b93_A_131b93   A     FMTFORMIC ACID A - 18
1b93_A_131b93   A     FMTFORMIC ACID H - 19
1b93_A_131b93   A     FMTFORMIC ACID D - 20
1b93_A_131b93   A     FMTFORMIC ACID K - 23
1b93_A_131b93   A     FMTFORMIC ACID L - 26
1bfd_*_3711bfd   *     TPPTHIAMINE DIPHOSPHATE E - 375
1bfd_*_3711bfd   *     TPPTHIAMINE DIPHOSPHATE S - 376
1bfd_*_3711bfd   *     TPPTHIAMINE DIPHOSPHATE T - 377
1bfd_*_3711bfd   *     TPPTHIAMINE DIPHOSPHATE S - 378
1bfd_*_3711bfd   *     TPPTHIAMINE DIPHOSPHATE T - 379
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE L - 158
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE M - 159
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE C - 160
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE E - 161
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE A - 163
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE L - 164
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE F - 167
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE Y - 168
1eke_A_201eke   A     MSESELENOMETHIONINE V - 20
1eke_A_201eke   A     MSESELENOMETHIONINE I - 25
1eke_A_201eke   A     MSESELENOMETHIONINE E - 26
1eke_A_201eke   A     MSESELENOMETHIONINE K - 27
1eke_A_201eke   A     MSESELENOMETHIONINE E - 28
1elj_A_2241elj   A     GLCGLUCOSE W - 230
1eu1_A_3961eu1   A     GLCGLUCOSE R - 401
1eu1_A_3961eu1   A     GLCGLUCOSE D - 404
1fi4_A_3071fi4   A     MSESELENOMETHIONINE Y - 310
1fi4_A_3071fi4   A     MSESELENOMETHIONINE Y - 311
1fi4_A_3071fi4   A     MSESELENOMETHIONINE L - 312
1fi4_A_3071fi4   A     MSESELENOMETHIONINE A - 313
1h5r_A_491h5r   A     THMTHYMIDINE I - 55
1hye_A_281hye   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE I - 32
1hye_A_281hye   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 33
1hye_A_281hye   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE R - 34
1hye_A_281hye   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE E - 35
1hye_A_281hye   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE H - 36
1hye_A_281hye   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 37
1i19_A_4311i19   A     EDO1,2-ETHANEDIOL T - 431
1i19_A_4311i19   A     EDO1,2-ETHANEDIOL E - 432
1i19_A_4311i19   A     FADFLAVIN-ADENINE DINUCLEOTIDE E - 432
1j5y_A_711j5y   A     MSESELENOMETHIONINE V - 71
1j5y_A_711j5y   A     MSESELENOMETHIONINE S - 72
1j5y_A_711j5y   A     MSESELENOMETHIONINE R - 73
1j5y_A_711j5y   A     MSESELENOMETHIONINE L - 74
1j5y_A_711j5y   A     MSESELENOMETHIONINE V - 75
1j5y_A_711j5y   A     NINICKEL (II) ION V - 77
1j5y_A_711j5y   A     NINICKEL (II) ION H - 79
1j5y_A_711j5y   A     MSESELENOMETHIONINE P - 81
1j5y_A_711j5y   A     MSESELENOMETHIONINE I - 84
1j5y_A_711j5y   A     NINICKEL (II) ION I - 84
1j5y_A_711j5y   A     MSESELENOMETHIONINE K - 85
1j5y_A_711j5y   A     NINICKEL (II) ION E - 87
1j5y_A_711j5y   A     NINICKEL (II) ION L - 88
1jv1_A_1621jv1   A     UD1URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE M - 165
1jv1_A_1621jv1   A     UD1URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE S - 167
1kol_A_3641kol   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE F - 379
1nkx_A_5961nkx   A     NAGN-ACETYL-D-GLUCOSAMINE Q - 609
1nkx_A_5961nkx   A     NAGN-ACETYL-D-GLUCOSAMINE H - 613
1nkx_A_5961nkx   A     NAGN-ACETYL-D-GLUCOSAMINE Q - 614
1nkx_A_5961nkx   A     NAGN-ACETYL-D-GLUCOSAMINE L - 617
1nkx_A_5961nkx   A     NAGN-ACETYL-D-GLUCOSAMINE F - 618
1nml_A_951nml   A     CITCITRIC ACID D - 95
1qy7_A_21qy7   A     NINICKEL (II) ION K - 2
1urs_A_2491urs   A     MLRMALTOTRIOSE W - 255
1vk3_A_2871vk3   A     MSESELENOMETHIONINE V - 287
1vk3_A_2871vk3   A     MSESELENOMETHIONINE R - 296
1vk3_A_2871vk3   A     MSESELENOMETHIONINE I - 297
1vk3_A_2871vk3   A     MSESELENOMETHIONINE L - 298
1vk3_A_2871vk3   A     MSESELENOMETHIONINE I - 300
1vk3_A_2871vk3   A     MSESELENOMETHIONINE A - 301
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1atg_*_31atg   * MOBANION-BINDING POCKET LOCATED AT THE INTERFACE BETWEEN THE 2 DOMAINS OF THE PROTEIN. BINDS BOTH MOLYBDATE AND TUNGSTATE.T - 9
1atg_*_31atg   * MOBANION-BINDING POCKET LOCATED AT THE INTERFACE BETWEEN THE 2 DOMAINS OF THE PROTEIN. BINDS BOTH MOLYBDATE AND TUNGSTATE.N - 10

Clusters included in this Subclass
CLUSTER: EH.2.78
CLUSTER: EH.3.18
CLUSTER: EH.3.19
CLUSTER: EH.4.6
CLUSTER: EH.5.6