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Information on SUBCLASS 2.1.15
Subclass Accession number: 2764
Subclass: 2.1.15 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 13

Average sequence ID (%) : 12.1 +/- 17.0
Average RMSD (Å) : 0.785 +/- 0.195

Consensus geometry
d (Å): 7 delta (°): 45-90 theta (°): 90-135 rho (°): 270-315
Consensus Sequence: XhXpXX
(φψ)-conformation: bbabaa
Pattern: [CFGIKLT]x[agilv]x[adeknrs][degps]x[adegs][acflmvy]xxx[almvy][ADEKQST]
Conservation:-0.842-0.4821.189-1.6340.4950.8521.2880.510-0.501-0.963-1.050-0.237-0.2601.637
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1f74_A_1841f74   A185198IWAGFDEMMLPAASEEE--GGGHHHHHHbbxabaaaaaaaaa
1f9v_A_5661f9v   A566579CKLESEEMVEIILKEE-SSGGGHHHHHHbxbabaaaaaaaaa
1g8m_A_1441g8m   A144157TVVCDPADYSSVAKEEE--GGGHHHHHHxbbabaaaaaaaaa
1gh2_A_41gh2   A518KPVGSDPDFQPELSEEE-SGGGHHHHHHxwbabaaaaaaaaa
1gpu_A_621gpu   A6376FVLSNGHAVALLYSEEESSGGGHHHHHHbbxaxaaaaaaaaa
1itz_A_711itz   A7285FVLSAGHGCMLQYAEEESSGGGHHHHHHbbxaxaaaaaaaaa
1lj8_A_591lj8   A6275GVGLRSEDRKARDDEEB-STTHHHHHHHxbbabaaaaaaaaa
1o1z_A_931o1z   A96109IEIKEREAADAVLEEEE--GGGHHHHHHxxxabaaaaaaaaa
1pkx_A_1431pkx   A143156TVVCEPEDYVVVSTEEE--GGGHHHHHHxbbabaaaaaaaaa
1q0b_A_2021q0b   A202215ITVHNKDEVYQILEEE--SGGGHHHHHHxxbabaaaaaaaaa
1qgd_A_591qgd   A6073FVLSNGHGSMLIYSEEESSGGGHHHHHHbbxaxaaaaaaaaa
1qlt_A_2761qlt   A281294ITLPKDGDLKQAVDEEE-STTHHHHHHHbxbaxaaaaaaaaa
1s5t_A_1821s5t   A183196LLSGDDASALDFMQEEE--GGGHHHHHHbbxabaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1f74_A_1841f74   A     NAY6,7,8,9-TETRAHYDROXY-5-METHYLCARBOXAMIDO-2-OXONONANOIC ACID G - 188
1f74_A_1841f74   A     NAY6,7,8,9-TETRAHYDROXY-5-METHYLCARBOXAMIDO-2-OXONONANOIC ACID F - 189
1f74_A_1841f74   A     NAY6,7,8,9-TETRAHYDROXY-5-METHYLCARBOXAMIDO-2-OXONONANOIC ACID D - 190
1f74_A_1841f74   A     NAY6,7,8,9-TETRAHYDROXY-5-METHYLCARBOXAMIDO-2-OXONONANOIC ACID E - 191
1g8m_A_1441g8m   A     MSESELENOMETHIONINE T - 144
1g8m_A_1441g8m   A     GGUANOSINE-5'-MONOPHOSPHATE T - 144
1g8m_A_1441g8m   A     MSESELENOMETHIONINE S - 154
1g8m_A_1441g8m   A     MSESELENOMETHIONINE V - 155
1g8m_A_1441g8m   A     GGUANOSINE-5'-MONOPHOSPHATE V - 155
1g8m_A_1441g8m   A     MSESELENOMETHIONINE A - 156
1g8m_A_1441g8m   A     GGUANOSINE-5'-MONOPHOSPHATE A - 156
1g8m_A_1441g8m   A     MSESELENOMETHIONINE K - 157
1g8m_A_1441g8m   A     GGUANOSINE-5'-MONOPHOSPHATE K - 157
1gpu_A_621gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE N - 67
1gpu_A_621gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE G - 68
1gpu_A_621gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE H - 69
1gpu_A_621gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE A - 70
1itz_A_711itz   A     TPPTHIAMINE DIPHOSPHATE A - 76
1itz_A_711itz   A     TPPTHIAMINE DIPHOSPHATE H - 78
1lj8_A_591lj8   A     MSESELENOMETHIONINE S - 59
1lj8_A_591lj8   A     MSESELENOMETHIONINE I - 60
1lj8_A_591lj8   A     MSESELENOMETHIONINE C - 61
1lj8_A_591lj8   A     MSESELENOMETHIONINE G - 62
1lj8_A_591lj8   A     MSESELENOMETHIONINE V - 63
1lj8_A_591lj8   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 63
1lj8_A_591lj8   A     MSESELENOMETHIONINE G - 64
1lj8_A_591lj8   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 65
1lj8_A_591lj8   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE R - 66
1lj8_A_591lj8   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE E - 68
1lj8_A_591lj8   A     MSESELENOMETHIONINE D - 69
1lj8_A_591lj8   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE D - 69
1lj8_A_591lj8   A     MSESELENOMETHIONINE R - 70
1lj8_A_591lj8   A     MSESELENOMETHIONINE A - 72
1lj8_A_591lj8   A     MSESELENOMETHIONINE R - 73
1lj8_A_591lj8   A     MSESELENOMETHIONINE L - 76
1q0b_A_2021q0b   A     NATETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE Y - 211
1q0b_A_2021q0b   A     NATETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE L - 214
1q0b_A_2021q0b   A     NATETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE E - 215
1q0b_A_2021q0b   A     NATETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE A - 218
1qgd_A_591qgd   A     TPPTHIAMINE DIPHOSPHATE N - 64
1qgd_A_591qgd   A     TPPTHIAMINE DIPHOSPHATE H - 66
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gpu_A_621gpu   A AC2THD BINDING SITE FOR CHAIN AH - 69
1qgd_A_591qgd   A TPACOFACTOR BINDINGH - 66

Clusters included in this Subclass
CLUSTER: EH.5.14