Logo
Information on SUBCLASS 2.3.1
Subclass Accession number: 2813
Subclass: 2.3.1 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 63

Average sequence ID (%) : 10.5 +/- 14.2
Average RMSD (Å) : 0.533 +/- 0.187

Consensus geometry
d (Å): 9 delta (°): 0-45 theta (°): 90-135 rho (°): 90-135
Consensus Sequence: XhppXX
(φψ)-conformation: bbapaa
Pattern: xx[afgilptv]x[adegknrst]xxx[aciklmtv]
Conservation:-1.099-0.4881.0150.0491.631-0.927-0.249-0.9501.018
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a49_A_2651a49   A268276SKIENHEGVEEE-SHHHHxxxabaaaa
1a79_A_181a79   A1927VIVFDKNGIEEE--HHHHbxbapaaaa
1chm_A_421chm   A4351AIFTSYHNIEEE-SHHHHbbxaxaaaa
1cpt_*_511cpt   -5260WIATKHADVEEE-SHHHHxbxaxaaaa
1dmh_A_2661dmh   A266274VEHTDPEAIEEE-SHHHHxxbaxaaaa
1dq3_A_2031dq3   A205213IDIKARNITEEE--HHHHbbbaxaaaa
1dq3_A_2941dq3   A298306LHVEEYSSLEEE--HHHHxbbaxaaaa
1dxe_A_1471dxe   A150158VQIESQQGVEEE-SHHHHxxbabaaaa
1dz4_A_621dz4   A6371WIATRGQLIEEE-SHHHHxbxabaaaa
1e0t_A_2161e0t   A219227SKIENQEGLEEE-SHHHHxxxabaaaa
1ebf_A_1661ebf   A170178EGIFSGTLSEEE--HHHHbbbabaaaa
1eup_A_371eup   A4048WLVTGYDEAEEE--HHHHbbbaxaaaa
1f0x_A_251f0x   A2532.LLTDPAKT.EE--HHHH.bbaxaaaa
1g9g_A_4851g9g   A490498NYGTDLGCAEEE--HHHHbbbaxaaaa
1g9z_A_731g9z   A7684YILSEIKPLEEE--HHHHxbbapaaaa
1go4_A_511go4   A5462LVTTDLELIEEE--HHHHbbxaxaaaa
1goi_A_1801goi   A184192AGAGGAFFLEEESSHHHHxbpabaaaa
1gso_A_671gso   A6876TIVGPEAPLEEE-SHHHHbbxaxaaaa
1gwi_A_411gwi   A4452WAVTHHAEAEEE-SHHHHxbxabaaaa
1h7s_A_301h7s   A3038QVVLSLSTAEEE--HHHHxxbabaaaa
1htw_A_1371htw   A142150LIAQTNLGKEEE-SHHHHbbxabaaaa
1i7g_A_2391i7g   A239247FVIHDMETLEEE-SHHHHxbbabaaaa
1icr_A_461icr   A4957IVASTEEGKEEE-SHHHHbbxaxaaaa
1io7_A_211io7   A2129WQVFSYRYTEEE-SHHHHxbbaxaaaa
1izc_A_1791izc   A182190PQIESVKGVEEE-SHHHHxbxabaaaa
1jl2_A_641jl2   A6775LYTDSHYLKEEE--HHHHbbbapaaaa
1jpz_A_471jpz   A5058RYLSSQRLIEEE--HHHHbxbabaaaa
1jqn_A_5011jqn   A503511PLFETLDDLEEE-SHHHHxbxabaaaa
1jyk_A_2141jyk   A215223YEIDSVQDYEE--SHHHHbxbabaaaa
1k3y_A_311k3y   A3341KFIKSAEDLEEE-SHHHHbxxabaaaa
1kbl_A_7391kbl   A742750TMIEIPRAAEEE-SHHHHbxbabaaaa
1kcx_A_2501kcx   A253261TKVMSKSAAEEE--HHHHxlxabaaaa
1kid_*_2261kid   -226233.KISNIREM.EE--HHHH.xbaxaaaa
1lfk_A_421lfk   A4351WMATAHAVVEEE-SHHHHxbxaxaaaa
1li4_A_1521li4   A153161ISEETTTGVEEE-SHHHHbbbabaaaa
1ltz_A_1931ltz   A194202MRIYGAGILEEE--HHHHxbbaxaaaa
1ml6_A_301ml6   A3240KFIQSPEDLEEE-SHHHHbxxabaaaa
1mlw_A_3261mlw   A327335LRVFGAGLLEEE--HHHHxbbaxaaaa
1n40_A_411n40   A4351WLVSSYALCEEE-SHHHHxxbabaaaa
1n8i_A_4271n8i   A431439IMDEERRTTEEE-SHHHHxxxabaaaa
1n97_A_431n97   A4452ALIFDPEGVEEE-SHHHHbxbaxaaaa
1nar_*_2211nar   -224232GFSTDPLDTEEE--HHHHbbbaxaaaa
1nox_*_521nox   -5563VVVRDPATKEEE--HHHHbxbaxaaaa
1nw3_A_1811nw3   A184192GVEKADIPAEEE-SHHHHbbbaxaaaa
1odo_A_381odo   A4149WSVSDPVLLEEE--HHHHxxbaxaaaa
1ono_A_1451ono   A146154LLPVDSEHNEEE-SHHHHxbxaxaaaa
1p2z_A_5921p2z   A599607NFRKDVNMVEEE--HHHHbbxaxaaaa
1pv9_A_191pv9   A2028VFIAKPVNVEEE--HHHHbbbaxaaaa
1pvd_A_5071pvd   A510518HRVATTGEWEEE-BHHHHbbbabaaaa
1pze_A_781pze   A7987RAEYSYEAAEEE-SHHHHbxbabaaaa
1q2y_A_21q2y   A412VIAKNEEQLEEE-SHHHHbxxaxaaaa
1q5d_A_491q5d   A5058WVLTRYHDVEEE-SHHHHxbxabaaaa
1qre_A_1721qre   A172179.VVTSQAEA.EE-SHHHH.bxabaaaa
1rfm_A_2061rfm   A206213.PTTDPAKA.EE--HHHH.wbaxaaaa
1srv_A_2261srv   A226233.KVSNVREL.EE--HHHH.xbaxaaaa
1toh_*_4661toh   -468476DVLDSPHTIEEE-SHHHHxxbabaaaa
1ued_A_551ued   A5664WQAHGYEVVEEE-SHHHHxbxaxaaaa
1ujn_A_1121ujn   A115123AFPTTTLAIEEE-SHHHHbbwabaaaa
1unn_C_2421unn   C251259EDIHHWSECEEE--HHHHbpxabaaaa
1usu_A_4981usu   A499507LFLTDPIDEEEE-SHHHHxxbabaaaa
1v33_A_1491v33   A152160IRVLDEWALEEE--HHHHbbxapaaaa
1vfr_A_481vfr   A5159IVIESDAAKEEE-SHHHHbxxaxaaaa
2prg_A_2472prg   A247255FVIYDMNSLEEE-SHHHHxbxabaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a49_A_2651a49   A     OXLOXALATE ION K - 269
1a49_A_2651a49   A     MGMAGNESIUM ION K - 269
1a49_A_2651a49   A     ATPADENOSINE-5'-TRIPHOSPHATE K - 269
1a49_A_2651a49   A     OXLOXALATE ION E - 271
1a49_A_2651a49   A     MGMAGNESIUM ION E - 271
1a49_A_2651a49   A     ATPADENOSINE-5'-TRIPHOSPHATE E - 271
1a79_A_181a79   A     AUGOLD ION R - 18
1a79_A_181a79   A     AUGOLD ION I - 20
1cpt_*_511cpt   *     HEMPROTOPORPHYRIN IX CONTAINING FE G - 64
1dxe_A_1471dxe   A     PO4PHOSPHATE ION Q - 151
1dxe_A_1471dxe   A     MGMAGNESIUM ION Q - 151
1dxe_A_1471dxe   A     PO4PHOSPHATE ION E - 153
1dxe_A_1471dxe   A     MGMAGNESIUM ION E - 153
1dz4_A_621dz4   A     HEMPROTOPORPHYRIN IX CONTAINING FE Y - 75
1eup_A_371eup   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 52
1goi_A_1801goi   A     GOLGLYCEROL A - 184
1goi_A_1801goi   A     GOLGLYCEROL G - 188
1goi_A_1801goi   A     GOLGLYCEROL A - 189
1goi_A_1801goi   A     GOLGLYCEROL F - 190
1goi_A_1801goi   A     GOLGLYCEROL F - 191
1gwi_A_411gwi   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 56
1h7s_A_301h7s   A     MSESELENOMETHIONINE L - 35
1h7s_A_301h7s   A     MSESELENOMETHIONINE S - 36
1h7s_A_301h7s   A     MSESELENOMETHIONINE V - 39
1h7s_A_301h7s   A     MSESELENOMETHIONINE K - 40
1htw_A_1371htw   A     ADPADENOSINE-5'-DIPHOSPHATE A - 137
1htw_A_1371htw   A     ADPADENOSINE-5'-DIPHOSPHATE R - 138
1i7g_A_2391i7g   A     AZ2(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL} ETHOXY)PHENYL]PROPANOIC ACID I - 241
1i7g_A_2391i7g   A     AZ2(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL} ETHOXY)PHENYL]PROPANOIC ACID L - 247
1i7g_A_2391i7g   A     AZ2(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL} ETHOXY)PHENYL]PROPANOIC ACID E - 251
1io7_A_211io7   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 33
1izc_A_1791izc   A     MGMAGNESIUM ION Q - 183
1izc_A_1791izc   A     PYRPYRUVIC ACID Q - 183
1izc_A_1791izc   A     MGMAGNESIUM ION E - 185
1izc_A_1791izc   A     PYRPYRUVIC ACID E - 185
1jpz_A_471jpz   A     140N-PALMITOYLGLYCINE R - 47
1jpz_A_471jpz   A     140N-PALMITOYLGLYCINE T - 49
1jpz_A_471jpz   A     140N-PALMITOYLGLYCINE Y - 51
1jqn_A_5011jqn   A     MNMANGANESE (II) ION L - 504
1jqn_A_5011jqn   A     DCO3,3-DICHLORO-2-PHOSPHONOMETHYL-ACRYLIC ACID L - 504
1jqn_A_5011jqn   A     DCO3,3-DICHLORO-2-PHOSPHONOMETHYL-ACRYLIC ACID F - 505
1jqn_A_5011jqn   A     MNMANGANESE (II) ION E - 506
1jqn_A_5011jqn   A     DCO3,3-DICHLORO-2-PHOSPHONOMETHYL-ACRYLIC ACID E - 506
1jyk_A_2141jyk   A     MSESELENOMETHIONINE I - 214
1k3y_A_311k3y   A     GTXS-HEXYLGLUTATHIONE L - 41
1k3y_A_311k3y   A     GTXS-HEXYLGLUTATHIONE R - 45
1lfk_A_421lfk   A     HEMPROTOPORPHYRIN IX CONTAINING FE M - 55
1li4_A_1521li4   A     NOC3-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-CYCLOPENTANE-1, 2-DIOL E - 156
1li4_A_1521li4   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 157
1li4_A_1521li4   A     NOC3-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-CYCLOPENTANE-1, 2-DIOL T - 157
1li4_A_1521li4   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 158
1li4_A_1521li4   A     NOC3-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-CYCLOPENTANE-1, 2-DIOL T - 158
1li4_A_1521li4   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 159
1li4_A_1521li4   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE G - 160
1li4_A_1521li4   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE H - 162
1ltz_A_1931ltz   A     FEFE (III) ION A - 199
1ltz_A_1931ltz   A     FEFE (III) ION G - 200
1ml6_A_301ml6   A     GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID L - 40
1ml6_A_301ml6   A     GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID K - 44
1mlw_A_3261mlw   A     FEFE (III) ION A - 332
1mlw_A_3261mlw   A     FEFE (III) ION G - 333
1n40_A_411n40   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 55
1n8i_A_4271n8i   A     MGMAGNESIUM ION M - 432
1n8i_A_4271n8i   A     GLVGLYOXYLIC ACID M - 432
1n8i_A_4271n8i   A     MGMAGNESIUM ION E - 434
1n8i_A_4271n8i   A     GLVGLYOXYLIC ACID E - 434
1n97_A_431n97   A     EGLETHYLENE GLYCOL L - 56
1nw3_A_1811nw3   A     ACTACETATE ION Y - 183
1nw3_A_1811nw3   A     SAMS-ADENOSYLMETHIONINE V - 185
1nw3_A_1811nw3   A     SAMS-ADENOSYLMETHIONINE E - 186
1nw3_A_1811nw3   A     SAMS-ADENOSYLMETHIONINE K - 187
1nw3_A_1811nw3   A     SAMS-ADENOSYLMETHIONINE A - 188
1nw3_A_1811nw3   A     SAMS-ADENOSYLMETHIONINE P - 191
1ono_A_1451ono   A     MW3MANGANESE ION, 3 WATERS COORDINATED D - 150
1ono_A_1451ono   A     MW3MANGANESE ION, 3 WATERS COORDINATED S - 151
1ono_A_1451ono   A     MW3MANGANESE ION, 3 WATERS COORDINATED E - 152
1q5d_A_491q5d   A     HEMPROTOPORPHYRIN IX CONTAINING FE F - 62
1ued_A_551ued   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 68
1v33_A_1491v33   A     PO4PHOSPHATE ION G - 149
1v33_A_1491v33   A     PO4PHOSPHATE ION H - 151
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1unn_C_2421unn   C AC2SO4 BINDING SITE FOR CHAIN DR - 265
1unn_C_2421unn   C AC1SO4 BINDING SITE FOR CHAIN CE - 269
1unn_C_2421unn   C AC1SO4 BINDING SITE FOR CHAIN CR - 272

Clusters included in this Subclass
CLUSTER: EH.1.105
CLUSTER: EH.1.15
CLUSTER: EH.2.12
CLUSTER: EH.2.58
CLUSTER: EH.3.12
CLUSTER: EH.3.166
CLUSTER: EH.3.97