ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 2.15.1

Subclass Accession number: 2869
Subclass: 2.15.1

Type: EH beta-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 3.5 (>75 %)  3.5.3 (>75 %)  3.5.3.1
GO : GO:0004053 (>75 %)  GO:0016810 (>75 %)  GO:0016813 (>75 %)  GO:0030145 (>75 %)  GO:0046914 (>75 %)
SCOP : 52767 (>75 %)  52768 (>75 %)  52769 (>75 %)

Number of loops: 3

Average sequence ID (%) : 45.0 +/- 11.6
Average RMSD (Å) : 0.200 +/- 0.000

Consensus geometry

d (Å): 11

delta (°): 90-135

theta (°): 135-180

rho (°): 0-45

Consensus Sequence:	hGGDHS
(φψ)-conformation:	bpwpaa

Pattern:	[AFI]	x	[LV]	[MV]	[IL]	[G]	[G]	[D]	[H]	[S]	[ILM]	[AT]	[IV]	[AG]	[AST]	[IL]	[ARS]	[AG]	[HV]	[A]
Conservation:	-1.197	-1.480	-0.338	-0.266	-0.107	1.406	1.406	1.406	2.425	0.388	-0.348	-0.513	0.141	-0.251	-0.687	-0.096	-1.027	-0.251	-0.999	0.388

Loops included in this Subclass

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1d3v_A_93	1d3v	A	ABH2(S)-AMINO-6-BORONOHEXANOIC ACID	D - 100
1d3v_A_93	1d3v	A	MNMANGANESE (II) ION	H - 101
1d3v_A_93	1d3v	A	ABH2(S)-AMINO-6-BORONOHEXANOIC ACID	H - 101
1d3v_A_93	1d3v	A	ABH2(S)-AMINO-6-BORONOHEXANOIC ACID	S - 102
1gq6_A_113	1gq6	A	MNMANGANESE (II) ION	H - 121
2cev_A_91	2cev	A	MNMANGANESE (II) ION	H - 99

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1gq6_A_113	1gq6	A	MNAMN BINDING SITE - CHAIN A	H - 121
2cev_A_91	2cev	A	MNAMN 301 BOUND TO HIS 99 ND1, ASP 122 OD2, ASP 126 OD2, ASP 226 OD2, A BRIDGING WATER HOH1 AND A TERMINAL WATER HOH MN 302 BOUND TO HIS 124 ND1, ASP 122 OD1, ASP 226 OD2, ASP 228 OD1, ASP 228 OD2 AND THE BRIDGING WATER HOH1	H - 99

Clusters included in this Subclass