Information on SUBCLASS 3.5.1 |
Subclass Accession number: 2929
Subclass: 3.5.1 Type: EH beta-alpha DB: ArchDB95 Image coordinates: Consensus coordinates: |
Number of loops: 78 Average sequence ID (%) : 30.5 +/- 22.8 Average RMSD (Å) : 0.433 +/- 0.181 Consensus geometry
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Consensus Sequence: | hhGXGXh |
(φψ)-conformation: | bbeapaa |
Pattern: | [acfilvy] | [acgilmtv] | [CFILMTV] | [acfilmvw] | [G] | x | [GS] | x | [afgilmtv] | [AEGS] | x | x | [acfgilmtv] | [acgilmv] | x | x |
Conservation: | 0.065 | -0.208 | 0.599 | -0.024 | 2.435 | -0.549 | 1.995 | -0.887 | -0.338 | 0.844 | -0.732 | -0.659 | -0.583 | -0.307 | -0.825 | -0.828 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1aog_A_191 | 1aog | A | 192 | 207 | VLTVGGGFISVEFAGI | EEEE-SSHHHHHHHHH | bbbbeaxaaaaaaaaa |
1b37_A_7 | 1b37 | A | 7 | 22 | VIVVGAGMSGISAAKR | EEEE--BHHHHHHHHH | bbbxeaxaaaaaaaaa |
1b6r_A_2 | 1b6r | A | 4 | 19 | VCVLGNGQLGRMLRQA | EEEES-SHHHHHHHHH | bbbxeabaaaaaaaaa |
1bg6_*_6 | 1bg6 | - | 7 | 22 | YAVLGLGNGGHAFAAY | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
1c0p_A_1006 | 1c0p | A | 1007 | 1022 | VVVLGSGVIGLSSALI | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1c1d_A_177 | 1c1d | A | 178 | 193 | VLVQGLGAVGGSLASL | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1cdo_A_195 | 1cdo | A | 196 | 211 | CAVFGLGAVGLAAVMG | EEEE--SHHHHHHHHH | bbbxMaxaaaaaaaaa |
1chu_A_11 | 1chu | A | 11 | 26 | VLIIGSGAAGLSLALR | EEEE--SHHHHHHHHH | bxbxeaxaaaaaaaaa |
1coy_*_11 | 1coy | - | 14 | 29 | ALVIGSGYGGAVAALR | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1d4d_A_128 | 1d4d | A | 128 | 143 | VVIIGSGGAGLAAAVS | EEEE--SHHHHHHHHH | bxbxeaxaaaaaaaaa |
1d5t_A_7 | 1d5t | A | 7 | 22 | VIVLGTGLTECILSGI | EEEE--SHHHHHHHHH | bbbbeapaaaaaaaaa |
1d7y_A_10 | 1d7y | A | 10 | 25 | VVVLGAGLASVSFVAE | EEEE--SHHHHHHHHH | xbbbeaxaaaaaaaaa |
1d7y_A_147 | 1d7y | A | 148 | 163 | LLIVGGGVIGLELAAT | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
1dlj_A_2 | 1dlj | A | 3 | 18 | IAVAGSGYVGLSLGVL | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1dxy_*_147 | 1dxy | - | 148 | 163 | VGVMGTGHIGQVAIKL | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
1e3i_A_198 | 1e3i | A | 199 | 214 | CAVFGLGCVGLSAIIG | EEEE--SHHHHHHHHH | bbbbMaxaaaaaaaaa |
1f8f_A_193 | 1f8f | A | 194 | 209 | FVTWGAGAVGLSALLA | EEEES-SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1fec_A_189 | 1fec | A | 190 | 205 | ALCVGGGYISIEFAGI | EEEE-SSHHHHHHHHH | bbbbeaxaaaaaaaaa |
1fl2_A_357 | 1fl2 | A | 358 | 373 | VAVIGGGNSGVEAAID | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
1gpe_A_24 | 1gpe | A | 27 | 42 | YIIAGGGLTGLTVAAK | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1gpj_A_169 | 1gpj | A | 170 | 185 | VLVVGAGEMGKTVAKS | EEEES--HHHHHHHHH | bbbbeapaaaaaaaaa |
1gtm_A_214 | 1gtm | A | 215 | 230 | IAIQGYGNAGYYLAKI | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1gv0_A_2 | 1gv0 | A | 3 | 18 | ITVIGAGNVGATTAFR | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1gz3_A_307 | 1gz3 | A | 307 | 322 | ILFLGAGEAALGIANL | EEEE--SHHHHHHHHH | bbxxeabaaaaaaaaa |
1h7w_A_190 | 1h7w | A | 190 | 205 | IALLGAGPASISCASF | EEEE--SHHHHHHHHH | bbbbMabaaaaaaaaa |
1h7w_A_334 | 1h7w | A | 335 | 350 | VIVLGAGDTAFDCATS | EEEE-SSHHHHHHHHH | bbbbeabaaaaaaaaa |
1het_A_194 | 1het | A | 195 | 210 | CAVFGLGGVGLSVIMG | EEEE--SHHHHHHHHH | bbbxMaxaaaaaaaaa |
1i0z_A_22 | 1i0z | A | 23 | 38 | ITVVGVGQVGMACAIS | EEEE--SHHHHHHHHH | bbbbMaxaaaaaaaaa |
1i8t_A_2 | 1i8t | A | 4 | 19 | YIIVGSGLFGAVCANE | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1id1_A_8 | 1id1 | A | 8 | 23 | FIVCGHSILAINTILQ | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
1j4a_A_148 | 1j4a | A | 149 | 164 | VGVVGTGHIGQVFMQI | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1j5p_A_2 | 1j5p | A | 3 | 18 | VLIIGMGNIGKKLVEL | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1jnr_A_25 | 1jnr | A | 25 | 40 | ILIIGGGFSGCGAAYE | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1jqb_A_1170 | 1jqb | A | 1170 | 1185 | VVVIGIGAVGLMGIAG | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1k0i_A_5 | 1k0i | A | 5 | 20 | VAIIGAGPSGLLLGQL | EEEE--SHHHHHHHHH | bxbxeaxaaaaaaaaa |
1kdg_A_217 | 1kdg | A | 219 | 234 | YIIVGAGPGGIIAADR | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
1kjq_A_14 | 1kjq | A | 15 | 30 | VMLLGSGELGKEVAIE | EEEES-SHHHHHHHHH | bbxbeaxaaaaaaaaa |
1kol_A_188 | 1kol | A | 189 | 204 | VYVAGAGPVGLAAAAS | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1ks9_A_2 | 1ks9 | A | 3 | 18 | ITVLGCGALGQLWLTA | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1lc0_A_9 | 1lc0 | A | 11 | 26 | VVVVGVGRAGSVRLRD | EEEE--SHHHHHHHHH | bbxbMaxaaaaaaaaa |
1leh_A_175 | 1leh | A | 176 | 191 | VSVQGLGNVAKALCKK | EEEE--SHHHHHHHHH | bxbxMaxaaaaaaaaa |
1li4_A_215 | 1li4 | A | 216 | 231 | AVVAGYGDVGKGCAQA | EEEE--SHHHHHHHHH | bbbxMaxaaaaaaaaa |
1lld_A_9 | 1lld | A | 10 | 25 | LAVIGAGAVGSTLAFA | EEEE--SHHHHHHHHH | bbbxMaxaaaaaaaaa |
1lqt_A_149 | 1lqt | A | 150 | 165 | AVVIGNGNVALDVARI | EEEE--SHHHHHHHHH | bbbxeabaaaaaaaaa |
1lqt_A_4 | 1lqt | A | 6 | 21 | IAIVGSGPSAFFAAAS | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
1lvl_*_173 | 1lvl | - | 174 | 189 | LVVVGGGYIGLELGIA | EEEE--SHHHHHHHHH | bbbxeabaaaaaaaaa |
1lvl_*_8 | 1lvl | - | 8 | 23 | LLIIGGGPGGYVAAIR | EEEE--SHHHHHHHHH | bbbbeabaaaaaaaaa |
1m66_A_15 | 1m66 | A | 18 | 33 | AVVFGSGAFGTALAMV | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1m6i_A_131 | 1m6i | A | 134 | 149 | FLLIGGGTAAFAAARS | EEEES-SHHHHHHHHH | bbbxeabaaaaaaaaa |
1mo9_A_216 | 1mo9 | A | 217 | 232 | VVVVGGSKTAVEYGCF | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
1mo9_A_46 | 1mo9 | A | 46 | 61 | AIFIGGGAAGRFGSAY | EEEE--SHHHHHHHHH | bbxxeaxaaaaaaaaa |
1mv8_A_2 | 1mv8 | A | 3 | 18 | ISIFGLGYVGAVCAGC | EEEE--STTHHHHHHH | bbbxeaxaaaaaaaaa |
1ng4_A_4 | 1ng4 | A | 7 | 22 | AVVIGGGIIGSAIAYY | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
1nhp_*_2 | 1nhp | - | 3 | 18 | VIVLGSSHGGYEAVEE | EEEE-SSHHHHHHHHH | bbbxeaxaaaaaaaaa |
1np3_A_19 | 1np3 | A | 19 | 34 | VAIIGYGSQGHAHACN | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1nvm_B_5 | 1nvm | B | 7 | 22 | VAIIGSGNIGTDLMIK | EEEE--SHHHHHHHHH | bbbbeabaaaaaaaaa |
1nyt_A_121 | 1nyt | A | 122 | 137 | ILLIGAGGASRGVLLP | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1obf_O_2 | 1obf | O | 4 | 19 | VAINGYGRIGRNILRA | EEEE--SHHHHHHHHH | bbbbMaxaaaaaaaaa |
1pj5_A_7 | 1pj5 | A | 7 | 22 | IVIIGAGIVGTNLADE | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1pze_A_22 | 1pze | A | 23 | 38 | VAMIGSGMIGGTMGYL | EEEE--SHHHHHHHHH | bbxxeaxaaaaaaaaa |
1q1r_A_151 | 1q1r | A | 152 | 167 | LVVIGGGYIGLEVAAT | EEEE--SHHHHHHHHH | bbxbeaxaaaaaaaaa |
1q1r_A_6 | 1q1r | A | 7 | 22 | VVIVGTGLAGVEVAFG | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1q9i_A_129 | 1q9i | A | 129 | 144 | VVVVGSGGAGFSAAIS | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
1qla_A_8 | 1qla | A | 8 | 23 | SLVIGGGLAGLRAAVA | EEEE--SHHHHHHHHH | bxbbeaxaaaaaaaaa |
1reo_A_35 | 1reo | A | 36 | 51 | VVVVGAGMSGLSAAYV | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1s3e_A_7 | 1s3e | A | 7 | 22 | VVVVGGGISGMAAAKL | EEEE--BHHHHHHHHH | bxbxeaxaaaaaaaaa |
1say_A_169 | 1say | A | 170 | 185 | VVILGGGVVGTEAAKM | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
1t2d_A_5 | 1t2d | A | 6 | 21 | IVLVGSGMIGGVMATL | EEEE--SHHHHHHHHH | bbxxeaxaaaaaaaaa |
1trb_*_147 | 1trb | - | 148 | 163 | VAVIGGGNTAVEEALY | EEEE-SSHHHHHHHHH | bbbbeabaaaaaaaaa |
1uuf_A_177 | 1uuf | A | 178 | 193 | VGVVGIGGLGHMGIKL | EEEE--SHHHHHHHHH | bbbxeabaaaaaaaaa |
1vj0_A_186 | 1vj0 | A | 187 | 202 | VVIQGAGPLGLFGVVI | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
2dap_*_4 | 2dap | - | 6 | 21 | VAIVGYGNLGRSVEKL | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
2nac_A_193 | 2nac | A | 194 | 209 | VGTVAAGRIGLAVLRR | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
2uag_A_8 | 2uag | A | 8 | 23 | VVIIGLGLTGLSCVDF | EEEE--SHHHHHHHHH | bbbbeabaaaaaaaaa |
3grs_*_189 | 3grs | - | 190 | 205 | SVIVGAGYIAVEMAGI | EEEE--SHHHHHHHHH | bbbbeaxaaaaaaaaa |
3grs_*_23 | 3grs | - | 23 | 38 | YLVIGGGSGGLASARR | EEEE--SHHHHHHHHH | bbbxeabaaaaaaaaa |
3lad_A_182 | 3lad | A | 183 | 198 | LGVIGAGVIGLELGSV | EEEE--SHHHHHHHHH | bbbbeabaaaaaaaaa |
9ldt_A_23 | 9ldt | A | 24 | 39 | ITVVGVGAVGMACAIS | EEEE--SHHHHHHHHH | bbbxeaxaaaaaaaaa |
PDB ligands within a cut-off distance of 6 Å in this subclass |
PDB Site Annotated loops in this subclass |
Loop | PDB | Chain | Site | Residue |
1e3i_A_198 | 1e3i | A | AC1NAD BINDING SITE FOR CHAIN A | G - 203 |
1gv0_A_2 | 1gv0 | A | NAANAD BINDING SITE FOR CHAIN A | G - 9 |
1gv0_A_2 | 1gv0 | A | NAANAD BINDING SITE FOR CHAIN A | N - 10 |
1gz3_A_307 | 1gz3 | A | AC1ATP BINDING SITE FOR CHAIN A | G - 313 |
1gz3_A_307 | 1gz3 | A | AC1ATP BINDING SITE FOR CHAIN A | E - 314 |
1gz3_A_307 | 1gz3 | A | AC1ATP BINDING SITE FOR CHAIN A | A - 315 |
1h7w_A_190 | 1h7w | A | AC6FAD BINDING SITE FOR CHAIN A | G - 194 |
1h7w_A_190 | 1h7w | A | AC6FAD BINDING SITE FOR CHAIN A | G - 196 |
1h7w_A_190 | 1h7w | A | AC6FAD BINDING SITE FOR CHAIN A | P - 197 |
1h7w_A_190 | 1h7w | A | AC6FAD BINDING SITE FOR CHAIN A | A - 198 |
Clusters included in this Subclass |
CLUSTER: EH.2.7 |
CLUSTER: EH.3.169 |
CLUSTER: EH.3.4 |
CLUSTER: EH.4.1 |
CLUSTER: EH.4.122 |