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Information on SUBCLASS 3.6.1
Subclass Accession number: 2933
Subclass: 3.6.1 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 52

Average sequence ID (%) : 9.8 +/- 12.6
Average RMSD (Å) : 0.525 +/- 0.209

Consensus geometry
d (Å): 11 delta (°): 45-90 theta (°): 135-180 rho (°): 225-270
Consensus Sequence: hXXXXXX
(φψ)-conformation: bblppaa
Pattern: xxx[afilmptv]x[adegknqrs]x[dehknprst]x[adegknqst][dehknqrst][afgiklmtv]x[adeknqrst]
Conservation:0.302-0.210-1.0500.324-1.0311.195-1.7440.991-1.6210.0480.8400.4800.2441.232
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1bjp_A_21bjp   A518IHILEGRSDEQKETEEEETT--HHHHHHbxbxxgxxaaaaaa
1c0a_A_2281c0a   A233246DVETSFMTAPQVREEEEEES--HHHHHHxbbbblbxaaaaaa
1ccw_A_1151ccw   A115128RVYAPGTPPEVGIAEE--TT--HHHHHHbbbxpvxxaaaaaa
1cwd_L_61cwd   L617..FFKNLSRKDAER..EEES--HHHHHH..bbxvxxaaaaaa
1dfo_A_2371dfo   A238251LILAKGGSEELYKKEEEESS--HHHHHHbbbbbvxxaaaaaa
1e79_A_2001e79   A202215IYVAIGQKRSTVAQEEEEES--HHHHHHbbbxbvxxaaaaaa
1f08_A_1891f08   A193206VLAVFGLAEVFFEAEEEEES--HHHHHHbbbbbvxxaaaaaa
1f1s_A_8911f1s   A893906YMMVPNIDRTSFDKEEEEES--HHHHHHbbbbxlbxaaaaaa
1g12_A_21g12   A212...YNGCSSSEQSA...EES--HHHHHH...xbvbxaaaaaa
1g94_A_51g94   A518FVHLFEWNWQDVAQEEEETT--HHHHHHbbxxpvxxaaaaaa
1gve_A_1331gve   A135148ELGLSNYVSWEVAEEEEEES--HHHHHHbxbbbvxxaaaaaa
1hsk_A_2751hsk   A275288MVNVDNGTATDYENEEE-SS--HHHHHHbxxablxbaaaaaa
1hx0_A_121hx0   A1326IVHLFEWRWVDIALEEEETT--HHHHHHbbxxxvxxaaaaaa
1iae_*_141iae   -1629PYTFAGVSGADQSAEEEEES--HHHHHHwbbbbvbxaaaaaa
1j0m_A_6381j0m   A642655YVLLPNKTSAQVGAEEEEET--HHHHHHbbxbxlbxaaaaaa
1jae_*_111jae   -1326IVHLFEWKWNDIADEEEETT--HHHHHHbbxxpvxxaaaaaa
1jla_A_4641jla   A466479VVTLTDTTNQKTELEEEESS--HHHHHHbbbbblbbaaaaaa
1k8k_A_1101k8k   A112125LTEPPLNTPENREYEEE-TT--HHHHHHbbbwxvxxaaaaaa
1kng_A_1121kng   A114127VGINYKDAADNARREEEEES--HHHHHHbbbxblbxaaaaaa
1l0w_A_2341l0w   A239252DLEMSFVEVEDVLEEEEEES--HHHHHHbbbbblbbaaaaaa
1lu4_A_10571lu4   A10591072VGIATRADVGAMQSEEEE-SS-HHHHHHbxbbbvbxaaaaaa
1m1n_B_4201m1n   B420432.TVYIGKDLWHLRS.EEEES--HHHHHH.bbbbvbbaaaaaa
1m3u_A_1771m3u   A177190LLVLECVPVELAKREEEEES--HHHHHHbbxbblbxaaaaaa
1mla_*_1301mla   -132145MAAIIGLDDASIAKEEEEES--HHHHHHbbxbbvbxaaaaaa
1mu2_A_4631mu2   A465478VKKLEQTTNQQAELEEEESS--HHHHHHbbxbblbbaaaaaa
1mww_A_601mww   A6477INLMAGRMEGTKKREEEETT--HHHHHHbbbxxgxxaaaaaa
1n7o_A_7911n7o   A795808YMLIPNVDRATFNQEEEEES--HHHHHHbbxbxvbxaaaaaa
1nnh_A_1131nnh   A118131DFEVERAKMEDIMREEEEET--HHHHHHbbbbpvxbaaaaaa
1nsj_*_551nsj   -5770VGVFVNEEPEKILDEEEESS--HHHHHHbbxbblxxaaaaaa
1o4u_A_2041o4u   A204217IVMLDNLSPEEVKDEEEEES--HHHHHHbbbxxlbxaaaaaa
1otf_A_31otf   A619LYIIEGRTDEQKETEEEES---HHHHHHbbbxpgxxaaaaaa
1p42_A_2571p42   A257270KFYSFRGGHSLNVKEEEEES--HHHHHHbbbbbvxbaaaaaa
1pne_*_1081pne   -112125LMGKEGVHGGMINKEEE-TT--HHHHHHbbxxxvxpaaaaaa
1pyf_A_1521pyf   A152164.IGVSNFSLEQLKE.EEEES--HHHHHH.bbbbvxxaaaaaa
1q15_A_51q15   A518FCVVYKGSDTDINNEEEEET--HHHHHHbbbbxlxbaaaaaa
1qpo_A_2181qpo   A218231LILLDNFAVWQTQTEEEEET--HHHHHHbbxxxlxxaaaaaa
1qtn_A_2801qtn   A281294IKPHDDCTVEQIYEEEEEES--HHHHHHxbwbxlbxaaaaaa
1qwk_A_1501qwk   A150162.VGVSNWNNDQISR.EEEES--HHHHHH.bbbbvxxaaaaaa
1qz5_A_1031qz5   A105118LTEAPLNPKANREKEEE-TT--HHHHHHbbbxplxwaaaaaa
1rhc_A_1891rhc   A189202HLMTVAAAPSTLKNEEEEES--HHHHHHbxbbblbxaaaaaa
1rlh_A_741rlh   A7689VILIRNAYPINILNEEEEES--HHHHHHbbbbbvbxaaaaaa
1rwh_A_6221rwh   A626639YMVAPGASVDLTRKEEEEET--HHHHHHbbbbxvxxaaaaaa
1s0y_A_31s0y   A619CDMRYGRTDEQKRAEEEETT--HHHHHHbxbxxgxxaaaaaa
1s0y_B_31s0y   B619CHIATGLSVARKQQEEEETT--HHHHHHbbbxxgxxaaaaaa
1st9_A_951st9   A98111VAVNVGESKIAVHNEEEEES--HHHHHHbxxxxvxxaaaaaa
1su4_A_6751su4   A675686..CFARVEPSHKSK..EEES--HHHHHH..bbblbxaaaaaa
1t15_A_16511t15   A16511664SMVVSGLTPEEFMLEEEEES--HHHHHHbbbbbvxxaaaaaa
1us0_A_1561us0   A156168.IGISNFNHLQVEM.EEEES--HHHHHH.bbbbvxxaaaaaa
1uxy_*_2911uxy   -292305LINEDNAKSEDVVQEEE-SS--HHHHHHxbxablxxaaaaaa
1v5x_A_541v5x   A5669VGVFRDQPPEEVLREEEESS--HHHHHHbxbbblbwaaaaaa
1yag_A_1031yag   A105118LTEAPMNPKSNREKEEE-TT--HHHHHHbbbxxvxpaaaaaa
1zpd_A_3171zpd   A317329.IRFPSVHLKDYLT.EEEES--HHHHHH.bbbxvbxaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1bjp_A_21bjp   A     OXP2-OXO-3-PENTENOIC ACID I - 2
1bjp_A_21bjp   A     OXP2-OXO-3-PENTENOIC ACID H - 6
1bjp_A_21bjp   A     OXP2-OXO-3-PENTENOIC ACID I - 7
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE E - 228
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE F - 229
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE T - 230
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE Q - 231
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE D - 233
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE V - 234
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE E - 235
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN Y - 117
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN A - 118
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN P - 119
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN G - 120
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN T - 121
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN P - 122
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN P - 123
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN V - 125
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN G - 126
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN I - 127
1cwd_L_61cwd   L     PPMPHOSPHONOMETHYL GROUP S - 11
1cwd_L_61cwd   L     PPMPHOSPHONOMETHYL GROUP R - 12
1dfo_A_2371dfo   A     FFO5-FORMYL-6-HYDROFOLIC ACID S - 254
1e79_A_2001e79   A     MGMAGNESIUM ION Y - 203
1e79_A_2001e79   A     MGMAGNESIUM ION Q - 208
1gve_A_1331gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 139
1gve_A_1331gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 140
1gve_A_1331gve   A     CITCITRIC ACID N - 140
1gve_A_1331gve   A     GOLGLYCEROL V - 142
1gve_A_1331gve   A     GOLGLYCEROL W - 144
1gve_A_1331gve   A     GOLGLYCEROL E - 145
1gve_A_1331gve   A     GOLGLYCEROL E - 148
1hx0_A_121hx0   A     EGLETHYLENE GLYCOL R - 20
1hx0_A_121hx0   A     EGLETHYLENE GLYCOL W - 21
1hx0_A_121hx0   A     EGLETHYLENE GLYCOL V - 22
1hx0_A_121hx0   A     EGLETHYLENE GLYCOL E - 27
1hx0_A_121hx0   A     EGLETHYLENE GLYCOL R - 30
1j0m_A_6381j0m   A     CACALCIUM ION Y - 656
1m3u_A_1771m3u   A     KPLKETOPANTOATE V - 179
1m3u_A_1771m3u   A     KPLKETOPANTOATE E - 181
1p42_A_2571p42   A     ZNZINC ION H - 265
1p42_A_2571p42   A     MYRMYRISTIC ACID H - 265
1qtn_A_2801qtn   A     DTDDITHIANE DIOL T - 288
1qtn_A_2801qtn   A     DTDDITHIANE DIOL E - 290
1qtn_A_2801qtn   A     DTDDITHIANE DIOL Q - 291
1qtn_A_2801qtn   A     DTDDITHIANE DIOL E - 294
1qz5_A_1031qz5   A     HIC4-METHYL-HISTIDINE A - 108
1rhc_A_1891rhc   A     F42COENZYME F420 M - 191
1rhc_A_1891rhc   A     F42COENZYME F420 T - 192
1rhc_A_1891rhc   A     F42COENZYME F420 V - 193
1rhc_A_1891rhc   A     ACNACETONE V - 193
1s0y_B_31s0y   B     MLAMALONIC ACID F - 3
1s0y_A_31s0y   A     MLAMALONIC ACID D - 7
1s0y_A_31s0y   A     MLAMALONIC ACID M - 8
1s0y_A_31s0y   A     MLAMALONIC ACID R - 9
1s0y_A_31s0y   A     MLAMALONIC ACID R - 12
1t15_A_16511t15   A     SEPPHOSPHOSERINE V - 1654
1t15_A_16511t15   A     SEPPHOSPHOSERINE S - 1655
1t15_A_16511t15   A     SEPPHOSPHOSERINE G - 1656
1t15_A_16511t15   A     SEPPHOSPHOSERINE L - 1657
1us0_A_1561us0   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 159
1us0_A_1561us0   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 160
1us0_A_1561us0   A     LDTIDD594 N - 160
1us0_A_1561us0   A     CITCITRIC ACID F - 161
1us0_A_1561us0   A     CITCITRIC ACID N - 162
1us0_A_1561us0   A     CITCITRIC ACID H - 163
1us0_A_1561us0   A     CITCITRIC ACID L - 164
1uxy_*_2911uxy   *     EPUURIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID V - 291
1zpd_A_3171zpd   A     CITCITRIC ACID R - 318
1zpd_A_3171zpd   A     CITCITRIC ACID F - 319
1zpd_A_3171zpd   A     CITCITRIC ACID P - 320
1zpd_A_3171zpd   A     CITCITRIC ACID S - 321
1zpd_A_3171zpd   A     CITCITRIC ACID V - 322
1zpd_A_3171zpd   A     CITCITRIC ACID H - 323
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gve_A_1331gve   A AC1NAP BINDING SITE FOR CHAIN AS - 139
1gve_A_1331gve   A AC1NAP BINDING SITE FOR CHAIN AN - 140
1gve_A_1331gve   A AC7GOL BINDING SITE FOR CHAIN AE - 145
1gve_A_1331gve   A AC7GOL BINDING SITE FOR CHAIN AE - 148
1us0_A_1561us0   A CT1CIT BINDING SITE FOR CHAIN AN - 162
1us0_A_1561us0   A CT1CIT BINDING SITE FOR CHAIN AH - 163

Clusters included in this Subclass
CLUSTER: EH.2.27
CLUSTER: EH.3.14
CLUSTER: EH.4.295
CLUSTER: EH.4.9
CLUSTER: EH.5.32
CLUSTER: EH.6.95