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Information on SUBCLASS 4.36.1
Subclass Accession number: 3138
Subclass: 4.36.1 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 9

Average sequence ID (%) : 21.5 +/- 28.0
Average RMSD (Å) : 0.822 +/- 0.268

Consensus geometry
d (Å): 7 delta (°): 45-90 theta (°): 135-180 rho (°): 45-90
Consensus Sequence: hphXXcXh
(φψ)-conformation: bbappgaa
Pattern: [adeqr][ILV][LPV][FILMV][aflvy][dht][AIPTV]x[ekp][CDGN]x[aegp][ehqrs][gl][AGKST][ACNT]
Conservation:-0.5182.7000.7491.542-1.1320.149-0.343-0.5920.1240.224-0.952-0.8930.163-0.945-0.189-0.087
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ekx_A_1011ekx   A101116AIVMRHPQEGAARLATEEEEEESSTTHHHHHHbbxbbbaxpvaaaaaa
1gv0_A_271gv0   A2742ELVLLDVVEGIPQGKAEEEEE-SSSSHHHHHHbbbbbbaxxgaaaaaa
1hwl_A_5491hwl   A552567QVPMATTEGCLVASTNEEEEE--STTHHHHHHbxwbxbaxxvaaaaaa
1ml4_A_1031ml4   A103118VIVIRHPKEGAARLAAEEEEEESSTTHHHHHHbbbbbbabpvaaaaaa
1pze_A_471pze   A4762DVVLYDVVKGMPEGKAEEEEE-SSSSHHHHHHxbbbbbaxxGaaaaaa
1q74_A_61q74   A621RLLFVHAHPDDESLSNEEEEEESSTTHHHHHHbbbbbbabxgaaaaaa
1t2d_A_291t2d   A2944DVVLFDIVKNMPHGKAEEEEE-SSSSHHHHHHxbbxxbaxxgaaaaaa
1uan_A_21uan   A318DLLVVAPHPDDGELGCEEEEEESSTTHHHHHHabbbxbabxgaaaaaa
1ur5_A_281ur5   A2843DIVLLDIVEGVPQGKAEEEEE-SSSSHHHHHHxbbxbbaxxgaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ekx_A_1011ekx   A     PALN-(PHOSPHONACETYL)-L-ASPARTIC ACID R - 105
1gv0_A_271gv0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 31
1gv0_A_271gv0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE D - 32
1gv0_A_271gv0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 33
1gv0_A_271gv0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 34
1gv0_A_271gv0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 37
1hwl_A_5491hwl   A     FBI7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID E - 559
1hwl_A_5491hwl   A     FBI7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID G - 560
1hwl_A_5491hwl   A     FBI7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID C - 561
1hwl_A_5491hwl   A     FBI7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID L - 562
1hwl_A_5491hwl   A     ADPADENOSINE-5'-DIPHOSPHATE V - 563
1hwl_A_5491hwl   A     ADPADENOSINE-5'-DIPHOSPHATE A - 564
1hwl_A_5491hwl   A     FBI7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID A - 564
1hwl_A_5491hwl   A     ADPADENOSINE-5'-DIPHOSPHATE S - 565
1hwl_A_5491hwl   A     FBI7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID S - 565
1hwl_A_5491hwl   A     ADPADENOSINE-5'-DIPHOSPHATE N - 567
1hwl_A_5491hwl   A     ADPADENOSINE-5'-DIPHOSPHATE R - 568
1hwl_A_5491hwl   A     FBI7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID R - 568
1hwl_A_5491hwl   A     ADPADENOSINE-5'-DIPHOSPHATE G - 569
1hwl_A_5491hwl   A     ADPADENOSINE-5'-DIPHOSPHATE R - 571
1ml4_A_1031ml4   A     PALN-(PHOSPHONACETYL)-L-ASPARTIC ACID R - 107
1q74_A_61q74   A     ZNZINC ION A - 12
1q74_A_61q74   A     ZNZINC ION H - 13
1q74_A_61q74   A     ZNZINC ION D - 15
1q74_A_61q74   A     ZNZINC ION D - 16
1t2d_A_291t2d   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE F - 33
1t2d_A_291t2d   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE D - 34
1t2d_A_291t2d   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 35
1t2d_A_291t2d   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 36
1t2d_A_291t2d   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE M - 39
1ur5_A_281ur5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 32
1ur5_A_281ur5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE D - 33
1ur5_A_281ur5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 34
1ur5_A_281ur5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 35
1ur5_A_281ur5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 38
1ur5_A_281ur5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE K - 42
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gv0_A_271gv0   A NAANAD BINDING SITE FOR CHAIN AD - 32
1ur5_A_281ur5   A AC1NAD BINDING SITE FOR CHAIN AI - 34

Clusters included in this Subclass
CLUSTER: EH.3.203
CLUSTER: EH.4.102