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Information on SUBCLASS 3.1.1
Subclass Accession number: 33
Subclass: 3.1.1
Type: EH beta-alpha
DB: ArchDB-KI
 Number of loops: 7

Average sequence ID (%) : 58.8 +/- 8.3
Average RMSD (Å) : 0.30 +/- 0.08

Consensus geometry
d (Å): 7 delta (°): 45-90 theta (°): 135-180 rho (°): 90-135
Consensus Sequence: LppSGpp
(φψ)-conformation: bbaagaa
Pattern: {IV}[V][AL][ST][EQT]{S}[G][KRT][ST][AP][HR]{AL}[V]{RS}
Conservation:0.6020.939-0.7350.196-0.722-0.1972.362-0.7220.033-0.4300.285-1.5130.939-1.038
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a3w_A_3981a3w   A399412IVLSTSGTTPRLVSEEE-SSSHHHHHHHxbxbaavaaaaaaa
1a3x_A_4001a3x   A400412.VLSTSGTTPRLVS.EE-SSSHHHHHHH.bxbNavaaaaaaa
1a49_A_4261a49   A428441IVLTESGRSAHQVAEEE-SSSHHHHHHHbbbbaavaaaaaaa
1aqf_A_4261aqf   A428441IVLTESGRSAHQVAEEE-SSSHHHHHHHbbbbaagaaaaaaa
1pkm_*_4271pkm   -428441IVLTESGRSAHQVAEEE-SSSHHHHHHHbbxbaavaaaaaaa
1pkn_*_4271pkn   -428441IVLTESGRSAHQVAEE--SSSHHHHHHHbbxbaavaaaaaaa
1pky_A_3731pky   A375388VVATQGGKSARAVREEE-SSSHHHHHHHxbbbaavaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a3w_A_3981a3w   A     FBPFRUCTOSE-1,6-DIPHOSPHATE L - 401
1a3w_A_3981a3w   A     FBPFRUCTOSE-1,6-DIPHOSPHATE S - 402
1a3w_A_3981a3w   A     FBPFRUCTOSE-1,6-DIPHOSPHATE T - 403
1a3w_A_3981a3w   A     FBPFRUCTOSE-1,6-DIPHOSPHATE S - 404
1a3w_A_3981a3w   A     FBPFRUCTOSE-1,6-DIPHOSPHATE G - 405
1a3w_A_3981a3w   A     FBPFRUCTOSE-1,6-DIPHOSPHATE T - 406
1a3w_A_3981a3w   A     FBPFRUCTOSE-1,6-DIPHOSPHATE T - 407
1a3w_A_3981a3w   A     FBPFRUCTOSE-1,6-DIPHOSPHATE P - 408
Bibliographic annotations
LoopPDBChainAnnotationResidue
1a3w_A_3981a3w   RefM.S.JURICA,A.MESECAR,P.J.HEATH,W.SHI,T.NOWAK,B.L.STODDARD. THE ALLOSTERIC REGULATION OF PYRUVATE KINASE BY FRUCTOSE-1,6-BISPHOSPHATE  STRUCTURE (LONDON) v.6;195,1998AFRUCTOSE-DI-P BINDING RESIDUES - 402
1a3w_A_3981a3w   RefM.S.JURICA,A.MESECAR,P.J.HEATH,W.SHI,T.NOWAK,B.L.STODDARD. THE ALLOSTERIC REGULATION OF PYRUVATE KINASE BY FRUCTOSE-1,6-BISPHOSPHATE  STRUCTURE (LONDON) v.6;195,1998AFRUCTOSE-DI-P BINDING RESIDUES - 404
1a3w_A_3981a3w   RefM.S.JURICA,A.MESECAR,P.J.HEATH,W.SHI,T.NOWAK,B.L.STODDARD. THE ALLOSTERIC REGULATION OF PYRUVATE KINASE BY FRUCTOSE-1,6-BISPHOSPHATE  STRUCTURE (LONDON) v.6;195,1998AFRUCTOSE-DI-P BINDING RESIDUET - 407

Clusters included in this Subclass
CLUSTER: EH.4.6