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Information on SUBCLASS 6.57.1
Subclass Accession number: 3397
Subclass: 6.57.1 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
GO : GO:0003723 (>75 %)  GO:0003724 (>75 %)  GO:0003968 (>75 %)  GO:0004175 (>75 %)  GO:0004197 (>75 %)  GO:0004386 (>75 %)  GO:0005524 (>75 %)  GO:0008233 (>75 %)  GO:0008234 (>75 %)  GO:0016462 (>50 %)  GO:0016772 (>75 %)  GO:0016779 (>75 %)  GO:0016817 (>50 %)  GO:0016818 (>50 %)  
SCOP : 88632 (>75 %)  88633 (>75 %)  88634 (>75 %)  
 Number of loops: 3

Average sequence ID (%) : 52.9 +/- 8.6
Average RMSD (Å) : 0.300 +/- 0.173

Consensus geometry
d (Å): 17 delta (°): 45-90 theta (°): 0-45 rho (°): 180-225
Consensus Sequence: WpIphppXhQ
(φψ)-conformation: bppbaaabaa
Pattern: [AT][KMV][W][KNR][I][NT][LY][KQ][DE][MT][AV][Q][IL][R][R][K][FL]
Conservation:-0.623-1.1163.247-0.6260.158-0.402-0.571-0.2800.063-0.720-0.7210.600-0.2820.6000.6000.600-0.525
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1aym_1_931aym   194110TKWNINLQEMAQIRRKFEEEE--S-S-HHHHHHHbbbxxbaaabaaaaaaa
1hxs_1_1061hxs   1106122AVWKITYKDTVQLRRKLEEEE--S-SSSHHHHHHbbbxxbaaabaaaaaaa
1pvc_1_1051pvc   1106122AMWRITYKDTVQLRRKLEEEE--S-SSSHHHHHHbbbxxbaaabaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1aym_1_931aym   1     DAOLAURIC ACID W - 96
1aym_1_931aym   1     DAOLAURIC ACID I - 98
1aym_1_931aym   1     DAOLAURIC ACID N - 99
1aym_1_931aym   1     DAOLAURIC ACID L - 100
1aym_1_931aym   1     DAOLAURIC ACID Q - 101
1hxs_1_1061hxs   1     PLMPALMITIC ACID I - 110
1hxs_1_1061hxs   1     PLMPALMITIC ACID T - 111
1hxs_1_1061hxs   1     PLMPALMITIC ACID Y - 112
1hxs_1_1061hxs   1     PLMPALMITIC ACID K - 113
1hxs_1_1061hxs   1     PLMPALMITIC ACID L - 122
1pvc_1_1051pvc   1     SPHSPHINGOSINE I - 110
1pvc_1_1051pvc   1     SPHSPHINGOSINE Y - 112
1pvc_1_1051pvc   1     SPHSPHINGOSINE L - 122
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1aym_1_931aym   1 POCA MOIETY MODELLED AS A 12-CARBON FATTY ACID IS OBSERVED IN PARTIAL OCCUPANCY IN THE HYDROPHOBIC POCKET WHERE ANTI-VIRAL COMPOUNDS BIND. THE HEAD GROUP OXYGENS CONTACT N1212 AND L1100.L - 100

Clusters included in this Subclass
CLUSTER: EH.6.363