Logo
Information on SUBCLASS 8.15.1
Subclass Accession number: 3492
Subclass: 8.15.1 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 4.2 (>75 %)  4.2.1 (>75 %)  4.2.1.47
GO : GO:0000287 (>75 %)  GO:0008446 (>75 %)  GO:0016829 (>75 %)  GO:0016835 (>75 %)  GO:0016836 (>75 %)  
SCOP : 51734 (>75 %)  51735 (>75 %)  51751 (>75 %)  52517 (>75 %)  52518 (>75 %)  88749 (>75 %)  
Number of loops: 4

Average sequence ID (%) : 68.8 +/- 7.4
Average RMSD (Å) : 0.150 +/- 0.058

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 0-45 rho (°): 90-135
Consensus Sequence: HESPXRGXpFVT
(φψ)-conformation: bbeaappaapaa
Pattern: [H][E][S][P]x[R][G]x[ENT][F][V][T][R][K][IV][ST][DR][AS][ILV][AG][KNR][I]x
Conservation:2.1210.6220.1221.621-1.1380.6221.122-1.698-1.0411.1220.1220.6220.6220.622-0.118-0.418-0.977-0.597-0.534-0.675-0.7440.122-1.524
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1db3_A_1861db3   A186208HESPRRGETFVTRKITRAIANIAEE-TTS-TTSHHHHHHHHHHHHHbbeaappaaxaaaaaaaaaaaaa
1n7h_A_2151n7h   A215237HESPRRGENFVTRKITRALGRIKEE-TTS-TTSHHHHHHHHHHHHHbbeaappaaxaaaaaaaaaaaaa
1rpn_A_1801rpn   A180202HESPLRGIEFVTRKVTDAVARIKEE-TTS-TTSHHHHHHHHHHHHHbbeaappaaxaaaaaaaaaaaaa
1t2a_A_2091t2a   A209231HESPRRGANFVTRKISRSVAKIYEE-TTS-TTSHHHHHHHHHHHHHbbeaaxpaaxaaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1n7h_A_2151n7h   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE H - 215
1n7h_A_2151n7h   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE E - 216
1n7h_A_2151n7h   A     GDPGUANOSINE-5'-DIPHOSPHATE E - 216
1n7h_A_2151n7h   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE R - 219
1n7h_A_2151n7h   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE R - 220
1n7h_A_2151n7h   A     GDPGUANOSINE-5'-DIPHOSPHATE R - 220
1n7h_A_2151n7h   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 221
1n7h_A_2151n7h   A     GDPGUANOSINE-5'-DIPHOSPHATE N - 223
1n7h_A_2151n7h   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE F - 224
1n7h_A_2151n7h   A     GDPGUANOSINE-5'-DIPHOSPHATE F - 224
1n7h_A_2151n7h   A     GDPGUANOSINE-5'-DIPHOSPHATE V - 225
1n7h_A_2151n7h   A     GDPGUANOSINE-5'-DIPHOSPHATE T - 226
1n7h_A_2151n7h   A     GDPGUANOSINE-5'-DIPHOSPHATE K - 228
1rpn_A_1801rpn   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE H - 180
1rpn_A_1801rpn   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE E - 181
1rpn_A_1801rpn   A     GDPGUANOSINE-5'-DIPHOSPHATE E - 181
1rpn_A_1801rpn   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 184
1rpn_A_1801rpn   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE R - 185
1rpn_A_1801rpn   A     GDPGUANOSINE-5'-DIPHOSPHATE R - 185
1rpn_A_1801rpn   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 186
1rpn_A_1801rpn   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE E - 188
1rpn_A_1801rpn   A     GDPGUANOSINE-5'-DIPHOSPHATE E - 188
1rpn_A_1801rpn   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE F - 189
1rpn_A_1801rpn   A     GDPGUANOSINE-5'-DIPHOSPHATE F - 189
1rpn_A_1801rpn   A     GDPGUANOSINE-5'-DIPHOSPHATE V - 190
1rpn_A_1801rpn   A     GDPGUANOSINE-5'-DIPHOSPHATE T - 191
1rpn_A_1801rpn   A     GDPGUANOSINE-5'-DIPHOSPHATE K - 193
1t2a_A_2091t2a   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE H - 209
1t2a_A_2091t2a   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE E - 210
1t2a_A_2091t2a   A     GDPGUANOSINE-5'-DIPHOSPHATE E - 210
1t2a_A_2091t2a   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE R - 213
1t2a_A_2091t2a   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE R - 214
1t2a_A_2091t2a   A     GDPGUANOSINE-5'-DIPHOSPHATE R - 214
1t2a_A_2091t2a   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 215
1t2a_A_2091t2a   A     GDPGUANOSINE-5'-DIPHOSPHATE N - 217
1t2a_A_2091t2a   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE F - 218
1t2a_A_2091t2a   A     GDPGUANOSINE-5'-DIPHOSPHATE F - 218
1t2a_A_2091t2a   A     GDPGUANOSINE-5'-DIPHOSPHATE V - 219
1t2a_A_2091t2a   A     GDPGUANOSINE-5'-DIPHOSPHATE T - 220
1t2a_A_2091t2a   A     GDPGUANOSINE-5'-DIPHOSPHATE K - 222

Clusters included in this Subclass
CLUSTER: EH.7.93