ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 12.1.1

Subclass Accession number: 3578
Subclass: 12.1.1

Type: EH beta-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Number of loops: 6

Average sequence ID (%) : 64.0 +/- 20.5
Average RMSD (Å) : 0.983 +/- 0.382

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 135-180

rho (°): 315-360

Consensus Sequence:	YEPhWAIGTGKpATPp
(φψ)-conformation:	pbpaaaplalppppaa

Pattern:	[IV]	[IL]	[AV]	[Y]	[E]	[P]	[ILV]	[W]	[A]	[I]	[G]	[T]	[G]	[K]	[STV]	[AS]	[ST]	[GP]	[EQ]	[DQ]	[A]	[NQ]	[es]	[V]	[CH]	[EGK]	[ehkw]	[IL]	[R]	[AGKRS]	[FIVW]	[LV]	[KRS]	[DERST]	x
Conservation:	0.065	-0.175	-0.532	1.592	0.707	1.592	-0.314	3.363	0.264	0.264	1.149	0.707	1.149	0.707	-0.804	-0.345	-0.121	-0.211	0.065	-0.253	0.264	-0.253	-1.280	0.264	-0.143	-0.955	-1.559	-0.164	0.707	-1.226	-0.948	-0.383	-0.596	-1.167	-1.426

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1mo0_A_159	1mo0	A	160	194	VIAYEPVWAIGTGKTASGEQAQEVHEWIRAFLKEK	EEEE--GGGTTTS----HHHHHHHHHHHHHHHHHH	bxbxbpaaaxvavxxxxaaaaaaaaaaaaaaaaaa
1o5x_A_160	1o5x	A	161	195	ILVYEPLWAIGTGKTATPEQAQLVHKEIRKIVKDT	EEEE--GGGSSSS----HHHHHHHHHHHHHHHHHH	bxbxbwaaabvavxbxxaaaaaaaaaaaaaaaaaa
1r2r_A_160	1r2r	A	161	195	VLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSN	EEEE--GGGSSSS----HHHHHHHHHHHHHHHHHH	bxbxbwaaabvavxbxxaaaaaaaaaaaaaaaaaa
1tcd_A_163	1tcd	A	164	198	VIAYEPVWAIGTGKVATPQQAQEVHELLRRWVRSK	EEEE--GGGTTTS----HHHHHHHHHHHHHHHHHH	bbbxbxaaaxUavxxxxaaaaaaaaaaaaaaaaaa
1tph_1_160	1tph	1	161	195	VLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKTH	EEEE--GGGTTTS----HHHHHHHHHHHHHHHHHH	bxbxbpaaaxvavxxxxaaaaaaaaaaaaaaaaaa
2btm_A_162	2btm	A	162	196	VIAYEPIWAIGTGKSSTPEDANSVCGHIRSVVSRL	EEEE--GGGTTTS----HHHHHHHHHHHHHHHHHH	bbbxbpaaaxUavbxxxaaaaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1mo0_A_159	1mo0	A	ACTACETATE ION	E - 164
1mo0_A_159	1mo0	A	ACTACETATE ION	I - 169
1o5x_A_160	1o5x	A	3PY3-HYDROXYPYRUVIC ACID	V - 163
1o5x_A_160	1o5x	A	3PY3-HYDROXYPYRUVIC ACID	E - 165
1o5x_A_160	1o5x	A	3PY3-HYDROXYPYRUVIC ACID	I - 170
1tph_1_160	1tph	1	PGHPHOSPHOGLYCOLOHYDROXAMIC ACID	E - 165
1tph_1_160	1tph	1	PGHPHOSPHOGLYCOLOHYDROXAMIC ACID	A - 169
1tph_1_160	1tph	1	PGHPHOSPHOGLYCOLOHYDROXAMIC ACID	I - 170
1tph_1_160	1tph	1	PGHPHOSPHOGLYCOLOHYDROXAMIC ACID	G - 171
1tph_1_160	1tph	1	PGHPHOSPHOGLYCOLOHYDROXAMIC ACID	T - 172
2btm_A_162	2btm	A	PGA2-PHOSPHOGLYCOLIC ACID	E - 166
2btm_A_162	2btm	A	PGA2-PHOSPHOGLYCOLIC ACID	A - 170
2btm_A_162	2btm	A	PGA2-PHOSPHOGLYCOLIC ACID	I - 171
2btm_A_162	2btm	A	PGA2-PHOSPHOGLYCOLIC ACID	G - 172
2btm_A_162	2btm	A	PGA2-PHOSPHOGLYCOLIC ACID	T - 173
2btm_A_162	2btm	A	PGA2-PHOSPHOGLYCOLIC ACID	G - 174

Clusters included in this Subclass