ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 12.8.1

Subclass Accession number: 3585
Subclass: 12.8.1

Type: EH beta-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 3.2 (>75 %)  3.2.1 (>75 %)  3.2.1.8
GO : GO:0004175 (>75 %)  GO:0004222 (>75 %)  GO:0004553 (>50 %)  GO:0005509 (>75 %)  GO:0008233 (>75 %)  GO:0008237 (>75 %)  GO:0008270 (>75 %)  GO:0016798 (>50 %)  GO:0046914 (>75 %)
SCOP : 51445 (>75 %)  51487 (>75 %)  55485 (>75 %)  55486 (>75 %)  55519 (>75 %)

Number of loops: 4

Average sequence ID (%) : 50.0 +/- 19.0
Average RMSD (Å) : 0.300 +/- 0.082

Consensus geometry

d (Å): 19

delta (°): 45-90

theta (°): 90-135

rho (°): 315-360

Consensus Sequence:	phWSXXDhITVQXpXX
(φψ)-conformation:	bbpaabpabppbapaa

Pattern:	[IL]	x	[IV]	[ST]	[L]	[AST]	x	[IL]	[DE]	[IMV]	[W]	[S]	[AEG]	[AKQ]	[D]	[FL]	[I]	[DT]	[IV]	[EQ]	[AS]	[DS]	[AS]	x	[NT]	[T]	[AL]	[GKN]	x	[F]	[AG]	[DES]	[W]	[R]	[AE]	[KRT]
Conservation:	-0.053	-1.417	0.139	-0.182	0.327	-0.524	-1.324	-0.053	0.222	-0.255	3.241	0.327	-0.859	-0.711	1.159	-0.289	0.327	-0.326	0.139	0.185	-0.298	-0.332	-0.298	-1.182	-0.044	0.743	-0.631	-0.753	-0.919	1.159	-0.082	-0.420	3.241	0.743	-0.421	-0.575

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1bud_A_49	1bud	A	49	84	IDISLSGLEIWSGKDLIDVEASAGNTLKSFGEWRAK	EEEEEEEEEE--S--SS---S-HHHHHHHHHHHHHH	bxxbxabbbbxaabxabxxbaxaaaaaaaaaaaaaa
1kuf_A_51	1kuf	A	51	86	IAITLALLDVWSEKDFITVQADAPTTAGLFGDWRER	EEEEEEEEEE-SS--SS---S-HHHHHHHHHHHHHH	bxxbxabbbbxaabxabxxbaxaaaaaaaaaaaaaa
1qua_A_49	1qua	A	49	84	LVITLSGIEMWSAADLITVQSSSRNTLKLFASWRET	EEEEEEEEEE-SSS-SS---SSHHHHHHHHHHHHHH	bxbbxaebbbxaabxabxxxaxaaaaaaaaaaaaaa
4aig_*_49	4aig	-	49	84	IRVSLTDLEIWSGQDFITIQSSSSNTLNSFGEWRER	EEEEEEEEEE-SS--SS---S-HHHHHHHHHHHHHH	bbxbxabbbbxaabxabxxbaxaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Clusters included in this Subclass