Logo
Information on SUBCLASS 15.3.1
Subclass Accession number: 3606
Subclass: 15.3.1 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 2.2 (>50 %)  2.2.1 (>50 %)  2.2.1.13.5 (>75 %)  3.5.3 (>75 %)  3.5.3.1
GO : GO:0004053 (>75 %)  GO:0004802 (>75 %)  GO:0005509 (>50 %)  GO:0016744 (>75 %)  GO:0016810 (>75 %)  GO:0016813 (>75 %)  GO:0030145 (>75 %)  GO:0046914 (>75 %)  
SCOP : 52517 (>75 %)  52518 (>75 %)  52767 (>75 %)  52768 (>75 %)  52769 (>75 %)  88735 (>75 %)  
 Number of loops: 3

Average sequence ID (%) : 72.6 +/- -29.5
Average RMSD (Å) : 0.167 +/- 0.058

Consensus geometry
d (Å): 11 delta (°): 45-90 theta (°): 135-180 rho (°): 90-135
Consensus Sequence: hTHDSIGhGEDGPTHQPhE
(φψ)-conformation: bblabaaaeaaeaaapwaa
Pattern: [IV][MWY][V][AMY][T][H][D][S][I][G][LV][G][E][D][G][P][T][H][Q][P][IV][E][HQT][LV][AV][HS][FL][R]
Conservation:-0.509-0.999-0.254-1.8580.2621.8080.777-0.254-0.2540.777-1.0150.7770.2620.7770.7771.2930.2621.8080.2621.293-0.5090.262-1.629-1.020-1.264-1.130-0.9630.262
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1gpu_A_4641gpu   A464491IWVATHDSIGVGEDGPTHQPIETLAHFREEEEE--SGGG-TT-TTT--SSHHHHHHbbxbxlabaaaeaaeaaabwaaaaaaaa
1itz_A_4691itz   A469496IYVMTHDSIGLGEDGPTHQPIEHLVSFREEEEE--SGGG-TT-TTT--SSHHHHHHbxxbxvabaaaeaaeaaaxxNaaaaaaa
1qgd_A_4561qgd   A456483VMVYTHDSIGLGEDGPTHQPVEQVASLREEEEE--SGGG-TT-TTTS-SSHHHHHHxbxbbvabaaaeaaeaaaxwaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1gpu_A_4641gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE D - 477
1gpu_A_4641gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE H - 481
1itz_A_4691itz   A     TPPTHIAMINE DIPHOSPHATE H - 486
1qgd_A_4561qgd   A     TPPTHIAMINE DIPHOSPHATE H - 473
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gpu_A_4641gpu   A AC4THD BINDING SITE FOR CHAIN BH - 481

Clusters included in this Subclass
CLUSTER: EH.16.14