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Information on SUBCLASS 5.22.1
Subclass Accession number: 383
Subclass: 5.22.1 PSSM
Type: HE alpha-beta
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.2 (>75 %)  3.2.1 (>75 %)  3.2.1.8 (>75 %)  4.2 (>75 %)  4.2.1 (>75 %)  4.2.1.46
GO : GO:0004553 (>50 %)  GO:0008460 (>75 %)  GO:0008509 (>75 %)  GO:0015075 (>75 %)  GO:0015098 (>75 %)  GO:0015103 (>75 %)  GO:0015412 (>75 %)  GO:0016462 (>75 %)  GO:0016798 (>50 %)  GO:0016817 (>75 %)  GO:0016818 (>75 %)  GO:0016820 (>75 %)  GO:0016829 (>75 %)  GO:0016835 (>75 %)  GO:0016836 (>75 %)  GO:0042625 (>75 %)  GO:0042626 (>75 %)  GO:0043225 (>75 %)  
SCOP : 51445 (>75 %)  51487 (>75 %)  51734 (>75 %)  51735 (>75 %)  51751 (>75 %)  53849 (>75 %)  53850 (>75 %)  53851 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 21.3 +/- 19.2
Average RMSD (Å) : 0.675 +/- 0.350

Consensus geometry
d (Å): 13 delta (°): 90-135 theta (°): 135-180 rho (°): 225-270
Consensus Sequence: hpGXhhDhh
(φψ)-conformation: aagpppabb
Pattern: [QS][EGS][KPQT]xxxx[IMV]x[ANS][G]xx[APY][DN][LTV][FV][FGIT]
Conservation:0.568-0.039-0.435-0.804-0.670-0.7630.0040.720-0.6400.1702.933-0.766-0.579-0.5531.6300.0870.269-1.133
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1amf_*_391amf   -3956SSTLARQIEAGAPADLFIHHHHHHHHHHT---SEEEaaaaaaaaaagxxxabbb
1atg_*_371atg   -3754SGPVYAQIVNGAPYNVFFHHHHHHHHHTT---SEEEaaaaaaaaaavpxbabbb
1j1n_A_541j1n   A5572QEQFNLMMASGDLPDVVGHHHHHHHHTSS---SEEEaaaaaaaaaavbxxabbb
1sbp_*_451sbp   -4562SGKQATSVINGIEADTVTHHHHHHHHHTT---SEEEaaaaaaaaaagxxxabbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1amf_*_391amf   *     MOOMOLYBDATE ION S - 39
1amf_*_391amf   *     MOOMOLYBDATE ION S - 40
1atg_*_371atg   *     WO4TUNGSTATE(VI)ION S - 37
1atg_*_371atg   *     WO4TUNGSTATE(VI)ION G - 38
1atg_*_371atg   *     EDO1,2-ETHANEDIOL V - 40
1atg_*_371atg   *     EDO1,2-ETHANEDIOL Q - 43
1atg_*_371atg   *     EDO1,2-ETHANEDIOL Y - 50
1j1n_A_541j1n   A     MAVD-MANNURONIC ACID S - 54
1j1n_A_541j1n   A     MAVD-MANNURONIC ACID Q - 55
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1amf_*_391amf   * MO4MOLYBDATE BINDING SITE.S - 39
1atg_*_371atg   * MOBANION-BINDING POCKET LOCATED AT THE INTERFACE BETWEEN THE 2 DOMAINS OF THE PROTEIN. BINDS BOTH MOLYBDATE AND TUNGSTATE.S - 37

Clusters included in this Subclass
CLUSTER: HE.6.52