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Information on SUBCLASS 8.39.1
Subclass Accession number: 4228
Subclass: 8.39.1 PSSM
Type: AR beta-beta link
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
GO : GO:0004175 (>75 %)  GO:0004190 (>75 %)  GO:0008233 (>75 %)  
SCOP : 50629 (>75 %)  50630 (>75 %)  50631 (>75 %)  
 Number of loops: 2

Average sequence ID (%) : 83.3 +/- 0.0
Average RMSD (Å) : 0.400 +/- 0.000

Consensus geometry
d (Å): 13 delta (°): 90-135 theta (°): 90-135 rho (°): 180-225
Consensus Sequence: VLEEMcLPGpWK
(φψ)-conformation: bbppbpppepbb
Pattern: [V][L][E][E][M][DN][L][P][G][KR][W][K][P][K][IM][I][G][G]
Conservation:-0.644-0.644-0.111-0.111-0.111-0.911-0.6440.9550.422-0.9113.088-0.1110.955-0.111-1.311-0.6440.4220.422
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1c6y_A_311c6y   A3249VLEEMDLPGRWKPKIIGGEE-S---SS--EEEEEEEbbxxbbxxexbbwbbxbb
1kzk_A_321kzk   A3249VLEEMNLPGKWKPKMIGGEE-S----S--EEEEEEEbbppbxbxexbbwbbbbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1c6y_A_311c6y   A     MK1N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S) -HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE T - 31
1c6y_A_311c6y   A     MK1N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S) -HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE V - 32
1c6y_A_311c6y   A     MK1N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S) -HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE I - 47
1c6y_A_311c6y   A     MK1N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S) -HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE G - 48
1c6y_A_311c6y   A     MK1N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S) -HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE G - 49
1kzk_A_321kzk   A     JE2(R)-N-(2-METHYLBENZYL)-3-[(2S,3S)-2-HYDROXY-3-(3-HYDROXY-2-METHYLBENZOYL)AMINO-4-PHENYLBUTANOYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXAMIDE V - 32
1kzk_A_321kzk   A     EGLETHYLENE GLYCOL E - 34
1kzk_A_321kzk   A     EGLETHYLENE GLYCOL G - 40
1kzk_A_321kzk   A     EGLETHYLENE GLYCOL K - 41
1kzk_A_321kzk   A     EGLETHYLENE GLYCOL W - 42
1kzk_A_321kzk   A     EGLETHYLENE GLYCOL K - 43
1kzk_A_321kzk   A     EGLETHYLENE GLYCOL P - 44
1kzk_A_321kzk   A     JE2(R)-N-(2-METHYLBENZYL)-3-[(2S,3S)-2-HYDROXY-3-(3-HYDROXY-2-METHYLBENZOYL)AMINO-4-PHENYLBUTANOYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXAMIDE K - 45
1kzk_A_321kzk   A     JE2(R)-N-(2-METHYLBENZYL)-3-[(2S,3S)-2-HYDROXY-3-(3-HYDROXY-2-METHYLBENZOYL)AMINO-4-PHENYLBUTANOYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXAMIDE I - 47
1kzk_A_321kzk   A     JE2(R)-N-(2-METHYLBENZYL)-3-[(2S,3S)-2-HYDROXY-3-(3-HYDROXY-2-METHYLBENZOYL)AMINO-4-PHENYLBUTANOYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXAMIDE G - 48
1kzk_A_321kzk   A     JE2(R)-N-(2-METHYLBENZYL)-3-[(2S,3S)-2-HYDROXY-3-(3-HYDROXY-2-METHYLBENZOYL)AMINO-4-PHENYLBUTANOYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXAMIDE G - 49

Clusters included in this Subclass
CLUSTER: AR.8.89