Logo
Information on SUBCLASS 12.6.1
Subclass Accession number: 4287
Subclass: 12.6.1 PSSM
Type: AR beta-beta link
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 2.7 (>75 %)  2.7.1 (>75 %)  2.7.1.693.4 (>75 %)  3.4.21 (>75 %)  
GO : GO:0004175 (>75 %)  GO:0004252 (>75 %)  GO:0005351 (>50 %)  GO:0005386 (>50 %)  GO:0005509 (>75 %)  GO:0008233 (>75 %)  GO:0008236 (>75 %)  GO:0008982 (>50 %)  GO:0015144 (>50 %)  GO:0015290 (>50 %)  GO:0015291 (>50 %)  GO:0015455 (>50 %)  GO:0016772 (>50 %)  GO:0016773 (>50 %)  GO:0051119 (>50 %)  
SCOP : 50493 (>75 %)  50494 (>75 %)  50514 (>75 %)  51229 (>75 %)  51261 (>75 %)  51262 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 27.3 +/- 22.1
Average RMSD (Å) : 1.150 +/- 0.404

Consensus geometry
d (Å): 15 delta (°): 90-135 theta (°): 90-135 rho (°): 315-360
Consensus Sequence: XhXHhhpXpXchpXhX
(φψ)-conformation: bbaaaaaapabaaabb
Pattern: [W][LV][ILV][STV][AP][AST][H][AC][FLY]xxx[KP][DKNR]x[ERS]x[LMY]x[AFV][IVY][FL]
Conservation:3.3390.1280.097-0.437-0.090-0.1842.1790.8630.100-0.771-0.728-0.9160.028-0.384-0.723-0.286-0.602-0.182-0.826-0.525-0.1180.039
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ddj_A_5971ddj   A597618WVLTAAHCLEKSPRPSSYKVILEEEE-GGGGTT-S-GGG-EEEEbbbbbaaaaaabaxaaabbbbb
1gj7_B_511gj7   B5172WVISATHCFIDYPKKEDYIVYLEEEE-GGGTTT---GGGEEEEEbbbbbaaaaaabaxaaabbbbb
1hav_A_381hav   A3859WLLVPSHAYKFEKDYEMMEFYFEEEEEGGGTTT-S-GGG-EEEEbbbbxaaaaaaxabaaaxbbbb
1kli_H_511kli   H5172WVVSAAHCFDKIKNWRNLIAVLEEEE-GGGGTT-S-GGGEEEEEbbbbbaaaaaaxabaaaxbbbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1gj7_B_511gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE H - 57
1gj7_B_511gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE C - 58
1gj7_B_511gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE F - 59
1gj7_B_511gj7   B     1326-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE I - 60
1kli_H_511kli   H     GOLGLYCEROL A - 56
1kli_H_511kli   H     BENBENZAMIDINE H - 57
1kli_H_511kli   H     GOLGLYCEROL F - 59
1kli_H_511kli   H     GOLGLYCEROL D - 60
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1hav_A_381hav   A PROCYS-HIS DYAD AND STABILIZING ELECTROSTATIC ENVIRONMENT ( CYS 172, HIS 44, TYR 143).H - 44

Clusters included in this Subclass
CLUSTER: AR.13.9