ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 12.17.1

Subclass Accession number: 4298
Subclass: 12.17.1

Type: AR beta-beta link
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
SCOP : 54510 (>75 %) 54511 (>75 %) 54512 (>75 %)

Number of loops: 3

Average sequence ID (%) : 69.1 +/- -22.8
Average RMSD (Å) : 0.167 +/- 0.058

Consensus geometry

d (Å): 15

delta (°): 45-90

theta (°): 135-180

rho (°): 0-45

Consensus Sequence:	GhNFPXcGhVMQKKTX
(φψ)-conformation:	bblppaapaaaalaba

Pattern:	[C]	[FL]	[ITV]	[Y]	[HK]	[AV]	[K]	[FV]	x	[G]	[LV]	[N]	[F]	[P]	[PS]	[DN]	[G]	[AP]	[V]	[M]	[Q]	[K]	[K]	[T]	[KMQ]	[G]	[W]
Conservation:	1.869	-0.803	-1.124	1.027	-0.635	-1.066	0.185	-1.010	-1.498	0.606	-0.853	0.606	0.606	1.027	-1.035	-0.423	0.606	-0.879	-0.236	0.185	0.185	0.185	0.185	0.185	-1.218	0.606	2.711

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ggx_A_117	1ggx	A	117	143	CFIYKVKFIGVNFPSDGPVMQKKTMGW	EEEEEEEEEEE---TTSTTTTT-EEEE	bxbbbbbbbbbvxpaaxaaaalaxaex
1mou_A_117	1mou	A	117	143	CFTYHVKFSGLNFPPNGPVMQKKTQGW	EEEEEEEEEEE---TTSTTTTT-EEEE	bxbbbbbbbbbvxpaaxaaaalaxaex
1uis_A_114	1uis	A	114	140	CLVYHAKVTGVNFPSNGAVMQKKTKGW	EEEEEEEEEEE---TTSTTTTT-EEEE	bxbbbbbbbbblxpaaxaaaalabaex

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ggx_A_117	1ggx	A	CRQ[2-(3-CARBAMOYL-1-IMINO-PROPYL)-4-(4-HYDROXY-BENZYLIDENE)-5-OXO-4,5-DIHYDRO-IMIDAZOL-1-YL]-ACETIC ACID	Y - 120
1ggx_A_117	1ggx	A	CRQ[2-(3-CARBAMOYL-1-IMINO-PROPYL)-4-(4-HYDROXY-BENZYLIDENE)-5-OXO-4,5-DIHYDRO-IMIDAZOL-1-YL]-ACETIC ACID	W - 143
1mou_A_117	1mou	A	CRQ[2-(3-CARBAMOYL-1-IMINO-PROPYL)-4-(4-HYDROXY-BENZYLIDENE)-5-OXO-4,5-DIHYDRO-IMIDAZOL-1-YL]-ACETIC ACID	V - 122
1mou_A_117	1mou	A	IODIODIDE ION	N - 128
1mou_A_117	1mou	A	IODIODIDE ION	F - 129
1mou_A_117	1mou	A	IODIODIDE ION	P - 130
1mou_A_117	1mou	A	IODIODIDE ION	P - 131
1uis_A_114	1uis	A	NRQ[(4R,5R)-2-[(1S)-1-AMINO-3-(METHYLSULFANYL)PROPYL]-5-HYDROXY-4-(4-HYDROXYBENZYL)-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]ACETALDEHYDE	Y - 117
1uis_A_114	1uis	A	CACALCIUM ION	Y - 117

Clusters included in this Subclass