Information on SUBCLASS 1.2.1 |
Subclass Accession number: 4419
Subclass: 1.2.1 Type: HH alpha-alpha DB: ArchDB95 Image coordinates: Consensus coordinates: |
Number of loops: 81 Average sequence ID (%) : 11.2 +/- 14.7 Average RMSD (Å) : 0.551 +/- 0.171 Consensus geometry
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Consensus Sequence: | XpXXX |
(φψ)-conformation: | aabaa |
Pattern: | x | x | x | [adegknqrst] | x | [dehkpqrst] | x | x | x |
Conservation: | -1.249 | -0.714 | -0.690 | 0.980 | 0.381 | 1.727 | 0.788 | -0.604 | -0.618 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1a32_*_50 | 1a32 | - | 69 | 77 | LRNKDVARY | HHHH-HHHH | aaaabaaaa |
1a6m_*_21 | 1a6m | - | 32 | 40 | LFKSHPETL | HHHH-HHHH | aaaabaaaa |
1a8i_*_728 | 1a8i | - | 731 | 739 | YYDRIPELR | HHHH-HHHH | aaaabaaaa |
1aq0_A_59 | 1aq0 | A | 61 | 69 | NLAASPAAA | HHHH-HHHH | aaaabaaaa |
1bgp_*_260 | 1bgp | - | 265 | 273 | RFAQSQQDF | HHHH-HHHH | aaaabaaaa |
1bwv_A_437 | 1bwv | A | 448 | 456 | AAKTCGALR | HHHH-HHHH | aaaabaaaa |
1d6a_A_160 | 1d6a | A | 176 | 184 | EAARFKYIE | HHHHBHHHH | aaaabaaaa |
1e1o_A_169 | 1e1o | A | 172 | 180 | DLIANDKSR | HHHH-HHHH | aaaabaaaa |
1e85_A_71 | 1e85 | A | 71 | 79 | EIWSDAASF | HHHHTHHHH | aaaabaaaa |
1em8_B_108 | 1em8 | B | 110 | 118 | DLRANPTAR | HHHH-HHHH | aaaabaaaa |
1f0i_A_314 | 1f0i | A | 316 | 324 | YDTVNPEES | HHHH-HHHH | aaaabaaaa |
1fp2_A_150 | 1fp2 | A | 153 | 161 | FLDKNPEYN | HHHH-HHHH | aaaabaaaa |
1fzy_A_124 | 1fzy | A | 129 | 137 | HYLRDRESF | HHHH-HHHH | aaaabaaaa |
1g2q_A_31 | 1g2q | A | 32 | 40 | PIFRNPGLF | HHHHSHHHH | aaaabaaaa |
1gjn_A_21 | 1gjn | A | 32 | 40 | LFTGHPETL | HHHH-HHHH | aaaabaaaa |
1gk8_A_437 | 1gk8 | A | 448 | 456 | ACKWSPELA | HHHH-HHHH | aaaabaaaa |
1gwu_A_259 | 1gwu | A | 265 | 273 | SFANSTQTF | HHHH-HHHH | aaaabaaaa |
1h6k_A_83 | 1h6k | A | 93 | 101 | LNARNYNFG | HHHH-HHHH | aaaabaaaa |
1hh2_P_201 | 1hh2 | P | 208 | 216 | MKLEIPEVE | HHHH-HHHH | aaaabaaaa |
1hlb_*_34 | 1hlb | - | 42 | 50 | IFAYDPSAQ | HHHH-THHH | aaaabaaaa |
1htj_F_307 | 1htj | F | 309 | 317 | IIFQDLEKL | HHHH-HHHH | aaaabaaaa |
1htj_F_314 | 1htj | F | 316 | 324 | KLKSRPAHL | HHHH-HHHH | aaaabaaaa |
1hyo_A_95 | 1hyo | A | 95 | 103 | RLRDDKELR | HHHH-HHHH | aaaaxaaaa |
1i2a_A_82 | 1i2a | A | 87 | 95 | ELGKNKRKL | HHHH-HHHH | aaaabaaaa |
1i2t_A_1041 | 1i2t | A | 1046 | 1054 | LLLASEDSL | HHHH-HHHH | aaaabaaaa |
1imj_A_190 | 1imj | A | 190 | 198 | CYLDKPEEW | HHHH-HHHH | aaaabaaaa |
1iv8_A_365 | 1iv8 | A | 369 | 377 | ATKRNPEAY | HHHH-HHHH | aaaabaaaa |
1ixh_*_140 | 1ixh | - | 149 | 157 | LAKVNEEWK | HHHH-HHHH | aaaabaaaa |
1izo_A_247 | 1izo | A | 257 | 265 | ALHEHPKYK | HHHHSTHHH | aaaabaaaa |
1j1n_A_93 | 1j1n | A | 96 | 104 | IDQYAPHIK | HHHH-HHHH | aaaabaaaa |
1j1q_A_174 | 1j1q | A | 175 | 183 | EAARFKYIE | HHHH-HHHH | aaaabaaaa |
1j1v_A_434 | 1j1v | A | 447 | 455 | LREESHDIK | HHHH-HHHH | aaaabaaaa |
1j7n_A_749 | 1j7n | A | 755 | 763 | VQKNAPKTF | HHHH-HHHH | aaaabaaaa |
1j93_A_170 | 1j93 | A | 175 | 183 | LAFAEPKVL | HHHH-HHHH | aaaabaaaa |
1jat_A_126 | 1jat | A | 128 | 136 | DWIKNEQGA | HHHH-HHHH | aggabaaaa |
1jb0_A_344 | 1jb0 | A | 347 | 355 | VLTTSWHAQ | HHHH-HHHH | aaaabaaaa |
1jx6_A_31 | 1jx6 | A | 34 | 42 | FLDEFPEQR | HHHH-HHHH | aaaabaaaa |
1kfs_A_784 | 1kfs | A | 791 | 799 | YFERYPGVL | HHHH-HHHH | aaaabaaaa |
1khc_A_296 | 1khc | A | 298 | 306 | TFNKLVSYR | HHHH-HHHH | aaaabaaaa |
1kvk_A_243 | 1kvk | A | 253 | 261 | RLIKFPEIM | HHHHSHHHH | aaaabaaaa |
1l5w_A_693 | 1l5w | A | 696 | 704 | WRKKDKVLD | HHHH-HHHH | aaaabaaaa |
1lns_A_576 | 1lns | A | 581 | 589 | KYSKDFNVF | HHHH-HHHH | aaaabaaaa |
1lp8_A_176 | 1lp8 | A | 177 | 185 | EAARFRYIQ | HHHHBHHHH | aaaabaaaa |
1lpy_A_137 | 1lpy | A | 138 | 146 | WYNQTPNRA | HHHHSHHHH | aaaabaaaa |
1m3q_A_106 | 1m3q | A | 113 | 121 | WGSVDSHFQ | HHHH-HHHH | aaaabaaaa |
1mbs_*_21 | 1mbs | - | 32 | 40 | LFKSHPETL | HHHH-THHH | aaaabaaaa |
1mla_*_20 | 1mla | - | 22 | 30 | MAASYPIVE | HHHH-HHHH | aaaabaaaa |
1mrj_*_159 | 1mrj | - | 160 | 168 | EAARYKFIE | HHHHBHHHH | aaaabaaaa |
1msw_D_670 | 1msw | D | 685 | 693 | VSVTVVAAV | HHHH-HHHH | aaaabaaaa |
1n8v_A_60 | 1n8v | A | 73 | 81 | LIKNEIEIW | HHHH-HHHH | aaaabaaaa |
1n97_A_241 | 1n97 | A | 246 | 254 | RVAESEEAA | HHHH-HHHH | aaaabaaaa |
1nij_A_135 | 1nij | A | 138 | 146 | QMNQFTIAQ | HHHH-HHHH | aaaabaaaa |
1nk4_A_729 | 1nk4 | A | 739 | 747 | YFESFPGVK | HHHH-HHHH | aaaabaaaa |
1nln_A_164 | 1nln | A | 178 | 186 | LERHSPYFR | HHHH-HHHH | aaaabaaaa |
1nst_A_778 | 1nst | A | 780 | 788 | LLRTEPAKV | HHHH-HHHH | aaaabaaaa |
1o0s_A_92 | 1o0s | A | 102 | 110 | LQDRNEKLF | HHHH-HHHH | aaaabaaaa |
1o26_A_181 | 1o26 | A | 194 | 202 | FKEKCPWTF | HHHH-HHHH | aaaabaaaa |
1o5l_A_91 | 1o5l | A | 97 | 105 | LLMKDRELL | HHHH-HHHH | aaaabaaaa |
1oaf_A_217 | 1oaf | A | 223 | 231 | KYAADEDAF | HHHH-HHHH | aaaabaaaa |
1oe8_A_183 | 1oe8 | A | 192 | 200 | LLASSPRLA | HHHH-HHHH | aaaabaaaa |
1ogc_A_72 | 1ogc | A | 73 | 81 | IKASNQENA | HHHHTHHHH | aaaabaaaa |
1omr_A_169 | 1omr | A | 175 | 183 | GTLANKEIL | HHHH-HHHH | aaaaxaaaa |
1pa2_A_257 | 1pa2 | A | 263 | 271 | SFASNQTLF | HHHH-HHHH | aaaabaaaa |
1phn_A_48 | 1phn | A | 59 | 67 | VYSKFPYTS | HHHH-THHH | aaaabaaaa |
1pjr_*_194 | 1pjr | - | 202 | 210 | LFDRVPDVL | HHHH-HHHH | aaaabaaaa |
1q44_A_228 | 1q44 | A | 230 | 238 | ELKKQTEVE | HHHHTHHHH | aaaabaaaa |
1qo8_A_418 | 1qo8 | A | 420 | 428 | LYKKAKMVR | HHHH-HHHH | aaaabaaaa |
1r0o_B_55 | 1r0o | B | 55 | 63 | MRRKCQECR | HHHH-HHHH | aaaabaaaa |
1r0w_A_630 | 1r0w | A | 633 | 641 | LQSLRPDFS | HHHH-HHHH | aaaabaaaa |
1r4p_A_166 | 1r4p | A | 167 | 175 | EALRFRQIQ | HHHH-HHHH | aaaabaaaa |
1r7i_A_241 | 1r7i | A | 254 | 262 | FAAVDPYRA | HHHH-HHHH | aaaabaaaa |
1rjd_A_35 | 1rjd | A | 52 | 60 | LKKFSRRAF | HHHH-HHHH | aaaabaaaa |
1say_A_330 | 1say | A | 330 | 338 | ALETDDALA | HHHH-HHHH | aaaabaaaa |
1tsy_*_114 | 1tsy | - | 128 | 136 | RVLHDDAFA | HHHH-HHHH | aaaaxaaaa |
1u9a_A_131 | 1u9a | A | 136 | 144 | IYCQNRVEY | HHHH-HHHH | aaaabaaaa |
1ual_A_201 | 1ual | A | 216 | 224 | TWLRRPELL | HHHH-HHHH | aaaabaaaa |
1uq5_A_161 | 1uq5 | A | 177 | 185 | EAARFQYIE | HHHH-HHHH | aaaabaaaa |
1vj7_A_181 | 1vj7 | A | 192 | 200 | FRYLNETEF | HHHH-HHHH | aaaabaaaa |
1yac_A_180 | 1yac | A | 187 | 195 | FSNHIPDYR | HHHH-HHHH | aaaabaaaa |
2aak_*_124 | 2aak | - | 129 | 137 | MYSESKREY | HHHH-HHHH | aaaabaaaa |
2mas_A_130 | 2mas | A | 135 | 143 | AARLEPRIV | HHHH-THHH | aaaabaaaa |
PDB ligands within a cut-off distance of 6 Å in this subclass |
PDB Site Annotated loops in this subclass |
Loop | PDB | Chain | Site | Residue |
1uq5_A_161 | 1uq5 | A | AC1ACT BINDING SITE FOR CHAIN A | M - 174 |
1uq5_A_161 | 1uq5 | A | AC1ACT BINDING SITE FOR CHAIN A | I - 192 |
Clusters included in this Subclass |
CLUSTER: HH.0.4 |
CLUSTER: HH.1.6 |
CLUSTER: HH.2.7 |