ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 1.2.10

Subclass Accession number: 4428
Subclass: 1.2.10

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Number of loops: 11

Average sequence ID (%) : 16.2 +/- 22.4
Average RMSD (Å) : 0.591 +/- 0.151

Consensus geometry

d (Å): 9

delta (°): 90-135

theta (°): 90-135

rho (°): 90-135

Consensus Sequence:	XXpXp
(φψ)-conformation:	aabaa

Pattern:	[DEKNQSY]	x	[ilv]	x	[aers]	[dehnt]	[aegpt]	[ADEQRS]	[FIKLMV]	[acfgil]	[adkt]	x	[filmt]
Conservation:	0.378	-1.023	1.044	-1.637	0.025	1.055	0.551	0.654	0.850	-1.489	-0.537	-0.926	1.055

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a53_*_234	1a53	-	234	246	SSLMRNPEKIKEF	HHHHH-TTHHHHH	aaaaabaaaaaaa
1a79_A_71	1a79	A	77	89	YARNVEERLCLKY	HHHHH-TTHHHHH	aaaaabaaaaaaa
1gwu_A_14	1gwu	A	24	36	NELRSDPRIAASI	HHHHH-TTHHHHH	aaaaabaaaaaaa
1jkv_A_88	1jkv	A	89	101	EDLKRDPSLATTM	HHHHH-TTHHHHH	aaaaabaaaaaaa
1jl6_A_24	1jl6	A	33	45	KFLSAHHDMAAVF	HHHHH-GGGHHHH	aaaaabaaaaaaa
1jl7_A_24	1jl7	A	33	45	KFISAHPEMAAVF	HHHHH-GGGHHHH	aaaaabaaaaaaa
1m50_A_156	1m50	A	167	179	KAIGSTGAFNDWI	HHHHH-TTHHHHH	aaaaabaaaaaaa
1pa2_A_14	1pa2	A	24	36	QALQSDTRIGASL	HHHTT-TTHHHHH	aaaaabaaaaaaa
1qo2_A_103	1qo2	A	103	115	SKVLEDPSFLKSL	HHHHH-TTHHHHH	aaaaabaaaaaaa
1r6d_A_89	1r6d	A	90	102	DRSIAGASVFTET	HHHHH--HHHHHH	aaaaabaaaaaaa
2hbg_*_24	2hbg	-	33	45	KFLSAHPQMAAVF	HHHHH-TTHHHHH	aaaaabaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1a53_*_234	1a53	*	IGPINDOLE-3-GLYCEROL PHOSPHATE	S - 234
1a53_*_234	1a53	*	IGPINDOLE-3-GLYCEROL PHOSPHATE	S - 235
1a79_A_71	1a79	A	AUGOLD ION	Y - 75
1a79_A_71	1a79	A	AUGOLD ION	R - 79
1a79_A_71	1a79	A	AUGOLD ION	L - 85
1a79_A_71	1a79	A	AUGOLD ION	C - 86
1a79_A_71	1a79	A	AUGOLD ION	L - 87
1a79_A_71	1a79	A	AUGOLD ION	Y - 89
1a79_A_71	1a79	A	AUGOLD ION	L - 90
1gwu_A_14	1gwu	A	HEMPROTOPORPHYRIN IX CONTAINING FE	R - 31
1gwu_A_14	1gwu	A	CACALCIUM ION	R - 31
1gwu_A_14	1gwu	A	HEMPROTOPORPHYRIN IX CONTAINING FE	A - 33
1gwu_A_14	1gwu	A	HEMPROTOPORPHYRIN IX CONTAINING FE	A - 34
1gwu_A_14	1gwu	A	CACALCIUM ION	A - 34
1gwu_A_14	1gwu	A	HEMPROTOPORPHYRIN IX CONTAINING FE	S - 35
1gwu_A_14	1gwu	A	CACALCIUM ION	S - 35
1gwu_A_14	1gwu	A	HEMPROTOPORPHYRIN IX CONTAINING FE	I - 36
1gwu_A_14	1gwu	A	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 37
1gwu_A_14	1gwu	A	CACALCIUM ION	L - 37
1gwu_A_14	1gwu	A	HEMPROTOPORPHYRIN IX CONTAINING FE	R - 38
1gwu_A_14	1gwu	A	CACALCIUM ION	R - 38
1gwu_A_14	1gwu	A	ACTACETATE ION	R - 38
1gwu_A_14	1gwu	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 41
1gwu_A_14	1gwu	A	CACALCIUM ION	F - 41
1gwu_A_14	1gwu	A	ACTACETATE ION	F - 41
1gwu_A_14	1gwu	A	HEMPROTOPORPHYRIN IX CONTAINING FE	H - 42
1gwu_A_14	1gwu	A	CACALCIUM ION	H - 42
1gwu_A_14	1gwu	A	ACTACETATE ION	H - 42
1gwu_A_14	1gwu	A	CACALCIUM ION	D - 43
1gwu_A_14	1gwu	A	CACALCIUM ION	C - 44
1jl6_A_24	1jl6	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 31
1jl6_A_24	1jl6	A	CNCYANIDE GROUP	F - 31
1jl6_A_24	1jl6	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 34
1jl6_A_24	1jl6	A	HEMPROTOPORPHYRIN IX CONTAINING FE	M - 41
1jl6_A_24	1jl6	A	HEMPROTOPORPHYRIN IX CONTAINING FE	V - 44
1jl6_A_24	1jl6	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 45
1jl6_A_24	1jl6	A	CNCYANIDE GROUP	F - 45
1jl7_A_24	1jl7	A	CNCYANIDE GROUP	L - 31
1m50_A_156	1m50	A	BCLBACTERIOCHLOROPHYLL A	D - 157
1m50_A_156	1m50	A	BCLBACTERIOCHLOROPHYLL A	L - 158
1m50_A_156	1m50	A	BCLBACTERIOCHLOROPHYLL A	I - 159
1m50_A_156	1m50	A	BCLBACTERIOCHLOROPHYLL A	T - 161
1m50_A_156	1m50	A	BCLBACTERIOCHLOROPHYLL A	W - 162
1m50_A_156	1m50	A	BCLBACTERIOCHLOROPHYLL A	T - 165
1m50_A_156	1m50	A	BCLBACTERIOCHLOROPHYLL A	I - 169
1m50_A_156	1m50	A	BCLBACTERIOCHLOROPHYLL A	F - 175
1m50_A_156	1m50	A	BCLBACTERIOCHLOROPHYLL A	I - 179
1m50_A_156	1m50	A	BCLBACTERIOCHLOROPHYLL A	F - 182
1m50_A_156	1m50	A	BCLBACTERIOCHLOROPHYLL A	W - 183
1pa2_A_14	1pa2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	G - 33
1pa2_A_14	1pa2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 36
1pa2_A_14	1pa2	A	CACALCIUM ION	I - 37
1pa2_A_14	1pa2	A	HEMPROTOPORPHYRIN IX CONTAINING FE	I - 37
1r6d_A_89	1r6d	A	DAU2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE	V - 89
1r6d_A_89	1r6d	A	DAU2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE	D - 90
1r6d_A_89	1r6d	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	T - 102
1r6d_A_89	1r6d	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	N - 103

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1gwu_A_14	1gwu	A	HEMHEM BINDING SITE FOR CHAIN A	R - 31
1gwu_A_14	1gwu	A	HEMHEM BINDING SITE FOR CHAIN A	A - 34
1gwu_A_14	1gwu	A	HEMHEM BINDING SITE FOR CHAIN A	S - 35
1gwu_A_14	1gwu	A	HEMHEM BINDING SITE FOR CHAIN A	R - 38
1gwu_A_14	1gwu	A	HEMHEM BINDING SITE FOR CHAIN A	F - 41
1gwu_A_14	1gwu	A	AC1ACT BINDING SITE FOR CHAIN A	H - 42
1gwu_A_14	1gwu	A	CA1CA BINDING SITE FOR CHAIN A	D - 43

Clusters included in this Subclass