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Information on SUBCLASS 8.1.1
Subclass Accession number: 451
Subclass: 8.1.1 PSSM
Type: HE alpha-beta
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 2.3 (>75 %)  2.3.1 (>75 %)  2.7 (>75 %)  2.7 (>75 %)  2.7.1 (>75 %)  2.7.1 (>75 %)  2.7.1.372.7.1.37
GO : GO:0004672 (>75 %)  GO:0004672 (>75 %)  GO:0005524 (>75 %)  GO:0008415 (>75 %)  GO:0016301 (>75 %)  GO:0016301 (>75 %)  GO:0016746 (>75 %)  GO:0016747 (>75 %)  GO:0016772 (>75 %)  GO:0016772 (>75 %)  GO:0016773 (>75 %)  GO:0016773 (>75 %)  GO:0030554 (>75 %)  
SCOP : 53900 (>75 %)  53901 (>75 %)  53902 (>50 %)  56111 (>75 %)  56111 (>75 %)  56112 (>75 %)  56112 (>75 %)  88854 (>75 %)  88854 (>75 %)  
 Number of loops: 14

Average sequence ID (%) : 31.0 +/- 22.4
Average RMSD (Å) : 0.693 +/- 0.220

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 90-135 rho (°): 135-180
Consensus Sequence: pXhpHhXhhpLp
(φψ)-conformation: aapbbaabppba
Pattern: [EKNQRT][E][aiklv][adekqrs][iltv][alm][hknqrs][aeknqr][AFILTV][DHKNQRS][FH][epr]x[FILV][ILTV][aknqrt][FLV][dehkry]xx[cfgiy]
Conservation:0.0152.333-0.696-0.8670.113-0.222-0.514-0.829-0.076-0.2212.8540.164-0.5900.5980.601-0.4760.757-0.727-0.827-0.838-0.551
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a06_*_651a06   -6585NEIAVLHKIKHPNIVALDDIYHHHHHHHT---TTB--EEEEEaaaaaaaaxbbaabxxbabbb
1gz8_A_461gz8   A5070REISLLKELNHPNIVKLLDVIHHHHHHTT---TTB--EEEEEaaaaaaaaxbbaabpxxabbb
1jks_A_581jks   A6383REVSILKEIQHPNVITLHEVYHHHHHHHH---TTB--EEEEEaaaaaaaaxbbaabxbbabbb
1k2p_A_4391k2p   A444464EEAKVMMNLSHEKLVQLYGVCHHHHHHHT---TTB--EEEEEaaaaaaaaxbbaabxxxabbb
1kob_A_891kob   A97117NEISIMNQLHHPKLINLHDAFHHHHHHTT--STTB--EEEEEaaaaaaaaaxbaabpxxabbb
1mp8_A_4621mp8   A470490QEALTMRQFDHPHIVKLIGVIHHHHHHHT---TTB--EEEEEaaaaaaaabbbaabpxxaebb
1mq4_A_1751mq4   A180200REVEIQSHLRHPNILRLYGYFHHHHHHHH---TTB--EEEEEaaaaaaaaxbbaabxxbaebb
1nvr_A_521nvr   A5474KEICINKMLNHENVVKFYGHRHHHHHHHT---TTB--EEEEEaaaaaaaaxbbaabpxbaebb
1o6l_A_1941o6l   A199219TESRVLQNTRHPFLTALKYAFHHHHHHHS---TTB--EEEEEaaaaaaaabbbaabxxxabbb
1o6y_A_501o6y   A5878REAQNAAALNHPAIVAVYDTGHHHHHHHT---TTB--EEEEEaaaaaaaabbbaabpxbabbb
1q41_A_961q41   A96116RELQIMRKLDHCNIVRLRYFFHHHHHHHT---TTB--EEEEEaaaaaaaaxbbaabxxxabbb
1rdq_E_851rdq   E90110NEKRILQAVNFPFLVKLEFSFHHHHHHTT---TTB--EEEEEaaaaaaaaxbbaabxxxabbb
1tki_A_601tki   A6787KEISILNIARHRNILHLHESFHHHHHHHHS--TTB--EEEEEaaaaaaaaxxbaabpxxabbb
1uu3_A_1241uu3   A129149RERDVMSRLDHPFFVKLYFTFHHHHHHHH--STTB--EEEEEaaaaaaaaxbbaabpxxabbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1gz8_A_461gz8   A     MBP1-[(2-AMINO-6,9-DIHYDRO-1H-PURIN-6-YL)OXY]-3-METHYL-2-BUTANOL V - 64
1mp8_A_4621mp8   A     ADPADENOSINE-5'-DIPHOSPHATE F - 468
1mp8_A_4621mp8   A     ADPADENOSINE-5'-DIPHOSPHATE E - 471
1mp8_A_4621mp8   A     ADPADENOSINE-5'-DIPHOSPHATE V - 484
1mq4_A_1751mq4   A     PO4PHOSPHATE ION H - 176
1mq4_A_1751mq4   A     PO4PHOSPHATE ION Q - 177
1mq4_A_1751mq4   A     PO4PHOSPHATE ION R - 180
1mq4_A_1751mq4   A     MGMAGNESIUM ION E - 181
1mq4_A_1751mq4   A     ADPADENOSINE-5'-DIPHOSPHATE E - 181
1mq4_A_1751mq4   A     ADPADENOSINE-5'-DIPHOSPHATE L - 194
1nvr_A_521nvr   A     STUSTAUROSPORINE E - 55
1nvr_A_521nvr   A     STUSTAUROSPORINE V - 68
1o6l_A_1941o6l   A     TPOPHOSPHOTHREONINE H - 196
1o6l_A_1941o6l   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER E - 200
1o6l_A_1941o6l   A     MNMANGANESE (II) ION E - 200
1o6l_A_1941o6l   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER T - 213
1o6y_A_501o6y   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER E - 59
1o6y_A_501o6y   A     MGMAGNESIUM ION E - 59
1o6y_A_501o6y   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER V - 72
1q41_A_961q41   A     IXM(Z)-1H,1'H-[2,3']BIINDOLYLIDENE-3,2'-DIONE-3-OXIME E - 97
1q41_A_961q41   A     IXM(Z)-1H,1'H-[2,3']BIINDOLYLIDENE-3,2'-DIONE-3-OXIME V - 110
1rdq_E_851rdq   E     TPOPHOSPHOTHREONINE H - 87
1rdq_E_851rdq   E     TPOPHOSPHOTHREONINE N - 90
1rdq_E_851rdq   E     MGMAGNESIUM ION E - 91
1rdq_E_851rdq   E     ADPADENOSINE-5'-DIPHOSPHATE E - 91
1rdq_E_851rdq   E     ATPADENOSINE-5'-TRIPHOSPHATE E - 91
1rdq_E_851rdq   E     MPD2-METHYL-2,4-PENTANEDIOL F - 100
1rdq_E_851rdq   E     ADPADENOSINE-5'-DIPHOSPHATE V - 104
1rdq_E_851rdq   E     ATPADENOSINE-5'-TRIPHOSPHATE V - 104
1uu3_A_1241uu3   A     SEPPHOSPHOSERINE Y - 126
1uu3_A_1241uu3   A     GOLGLYCEROL Y - 126
1uu3_A_1241uu3   A     GOLGLYCEROL V - 127
1uu3_A_1241uu3   A     GOLGLYCEROL T - 128
1uu3_A_1241uu3   A     SEPPHOSPHOSERINE R - 129
1uu3_A_1241uu3   A     GOLGLYCEROL E - 130
1uu3_A_1241uu3   A     LY4(9R)-9-[(DIMETHYLAMINO)METHYL]-6,7,10,11-TETRAHYDRO-9H,18H-5,21:12,17-DIMETHENODIBENZO[E,K]PYRROLO[3,4-H] [1,4,13]OXADIAZACYCLOHEXADECINE-18,20-DIONE E - 130
1uu3_A_1241uu3   A     GOLGLYCEROL R - 131
1uu3_A_1241uu3   A     LY4(9R)-9-[(DIMETHYLAMINO)METHYL]-6,7,10,11-TETRAHYDRO-9H,18H-5,21:12,17-DIMETHENODIBENZO[E,K]PYRROLO[3,4-H] [1,4,13]OXADIAZACYCLOHEXADECINE-18,20-DIONE M - 134
1uu3_A_1241uu3   A     GOLGLYCEROL S - 135
1uu3_A_1241uu3   A     GOLGLYCEROL H - 139
1uu3_A_1241uu3   A     GOLGLYCEROL P - 140
1uu3_A_1241uu3   A     GOLGLYCEROL F - 141
1uu3_A_1241uu3   A     LY4(9R)-9-[(DIMETHYLAMINO)METHYL]-6,7,10,11-TETRAHYDRO-9H,18H-5,21:12,17-DIMETHENODIBENZO[E,K]PYRROLO[3,4-H] [1,4,13]OXADIAZACYCLOHEXADECINE-18,20-DIONE V - 143
1uu3_A_1241uu3   A     GOLGLYCEROL Y - 146
1uu3_A_1241uu3   A     GOLGLYCEROL F - 147
1uu3_A_1241uu3   A     GOLGLYCEROL T - 148
1uu3_A_1241uu3   A     GOLGLYCEROL F - 149
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1o6l_A_1941o6l   A AC1ANP BINDING SITE FOR CHAIN AT - 213
1uu3_A_1241uu3   A AC1LY4 BINDING SITE FOR CHAIN AE - 130

Clusters included in this Subclass
CLUSTER: HE.10.4
CLUSTER: HE.8.1
CLUSTER: HE.9.1
CLUSTER: HE.9.4