ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 2.2.17

Subclass Accession number: 4578
Subclass: 2.2.17

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 3.2 (>50 %)  3.2.1 (>50 %)  3.2.1.4
GO : GO:0004553 (>50 %)  GO:0008810 (>50 %)  GO:0016798 (>50 %)
SCOP : 48207 (>50 %)  48208 (>50 %)  48213 (>50 %)

Number of loops: 2

Average sequence ID (%) : 11.1 +/- 0.0
Average RMSD (Å) : 0.600 +/- 0.000

Consensus geometry

d (Å): 11

delta (°): 90-135

theta (°): 135-180

rho (°): 90-135

Consensus Sequence:	XXGpSX
(φψ)-conformation:	aalpaa

Pattern:	x	[LW]	[EL]	x	[AS]	[PS]	[I]	[FG]	[SY]	[HM]	[CG]	[CS]	x	[KL]	x	[IL]	[CG]	[DV]	[KV]	x	[G]	[DS]	[S]	[SV]	[KS]	[FI]	[DK]
Conservation:	-0.746	0.526	-1.170	-0.958	0.314	0.102	1.586	-0.534	-0.322	0.102	0.102	0.526	-0.534	-0.746	-0.958	0.738	0.102	-0.958	-0.746	-1.170	3.281	0.314	1.586	-0.958	0.102	0.314	0.102

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1n93_X_130	1n93	X	130	156	ELEISSIFSHCCSLLIGVVIGSSSKIK	HHHHHHHHHHHHHHHHHHHHT-SHHHH	aaaaaaaaaaaaaaaaaaaavbaaaaa
1pfv_A_252	1pfv	A	252	278	VWLDAPIGYMGSFKNLCDKRGDSVSFD	HHHHHHHHHHHHHHHHHHHHT-SSHHH	aaaaaaaaaaaaaaaaaaaavxaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1pfv_A_252	1pfv	A	2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE	W - 253
1pfv_A_252	1pfv	A	2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE	D - 255
1pfv_A_252	1pfv	A	2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE	A - 256
1pfv_A_252	1pfv	A	2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE	P - 257
1pfv_A_252	1pfv	A	2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE	I - 258
1pfv_A_252	1pfv	A	2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE	G - 259
1pfv_A_252	1pfv	A	2FMS-(DIFLUOROMETHYL)HOMOCYSTEINE	Y - 260

Clusters included in this Subclass