ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 2.3.15

Subclass Accession number: 4593
Subclass: 2.3.15

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Number of loops: 3

Average sequence ID (%) : 44.8 +/- 11.8
Average RMSD (Å) : 0.400 +/- 0.100

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 90-135

rho (°): 315-360

Consensus Sequence:	pXhcQX
(φψ)-conformation:	aabpaa

Pattern:	[APQ]	x	[W]	[KS]	[HY]	[EQ]	[WY]	x	[K]	[H]	[G]	[ST]	[C]	[ACS]	[EQ]	[KNS]	x	[FY]	[DN]	[Q]	x	[AGT]	[Y]	[F]	[GK]	[KL]	[A]	[LV]	[DR]	[LM]	[KR]	[DN]
Conservation:	-1.054	-0.799	2.864	-0.611	0.449	-0.092	0.851	-1.318	0.487	1.675	0.883	-0.354	2.072	-0.746	-0.092	-0.746	-1.230	0.374	-0.043	0.487	-0.966	-1.010	1.279	0.883	-0.794	-0.966	0.091	-0.468	-0.729	-0.225	-0.072	-0.081

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ioo_A_82	1ioo	A	82	113	PSWKYQYIKHGSCCQKRYNQNTYFGLALRLKD	HHHHHHHHHTGGG-TTT--HHHHHHHHHHHHH	aaaaaaaaaaaaaaaaabbaaaaaaaaaaaaa
1iyb_A_87	1iyb	A	88	119	AFWSHEWEKHGTCAENVFDQHGYFKKALDLKN	HHHHHHHHHTGGGGTTT--HHHHHHHHHHHHH	aaaaaaaaaaaaaaaaabxaaaaaaaaaaaaa
1uca_A_77	1uca	A	79	110	QFWSHEWTKHGTCSESTFNQAAYFKLAVDMRN	HHHHHHHHHTGGGGTTT--HHHHHHHHHHHHH	aaaaaaaaaaaaaaaaabxaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ioo_A_82	1ioo	A	MANALPHA-D-MANNOSE	R - 110
1ioo_A_82	1ioo	A	NAGN-ACETYL-D-GLUCOSAMINE	K - 112
1ioo_A_82	1ioo	A	NAGN-ACETYL-D-GLUCOSAMINE	D - 113
1ioo_A_82	1ioo	A	MANALPHA-D-MANNOSE	D - 113
1ioo_A_82	1ioo	A	XYSXYLOPYRANOSE	D - 113
1iyb_A_87	1iyb	A	5GPGUANOSINE-5'-MONOPHOSPHATE	A - 88
1iyb_A_87	1iyb	A	5GPGUANOSINE-5'-MONOPHOSPHATE	F - 89
1iyb_A_87	1iyb	A	5GPGUANOSINE-5'-MONOPHOSPHATE	H - 92
1iyb_A_87	1iyb	A	5GPGUANOSINE-5'-MONOPHOSPHATE	E - 93
1iyb_A_87	1iyb	A	5GPGUANOSINE-5'-MONOPHOSPHATE	K - 96
1iyb_A_87	1iyb	A	5GPGUANOSINE-5'-MONOPHOSPHATE	H - 97
1uca_A_77	1uca	A	U2PPHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER	F - 80
1uca_A_77	1uca	A	U2PPHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER	H - 83
1uca_A_77	1uca	A	U2PPHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER	E - 84
1uca_A_77	1uca	A	U2PPHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER	K - 87
1uca_A_77	1uca	A	U2PPHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER	H - 88

Clusters included in this Subclass