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Information on SUBCLASS 3.1.6
Subclass Accession number: 4652
Subclass: 3.1.6 PSSM
Type: HH alpha-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 18

Average sequence ID (%) : 21.5 +/- 22.3
Average RMSD (Å) : 0.522 +/- 0.234

Consensus geometry
d (Å): 13 delta (°): 45-90 theta (°): 90-135 rho (°): 90-135
Consensus Sequence: XhphpXp
(φψ)-conformation: aalppaa
Pattern: xxx[fiklmv]xx[almw][ehknqr][ilmpvy][dhqst]x[adekst][ade]x[aglmv][acgkl][afilmv]
Conservation:-0.894-0.744-0.7630.350-1.075-0.1570.2931.1560.8770.642-0.669-0.2342.881-0.484-0.307-1.0050.133
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1f20_A_11331f20   A11361152EEWKWGKNPTMVEVLEEHHHHHHH---HHHHHHHaaaaaaalxxaaaaaaa
1fcy_A_3081fcy   A315331AGQLLPLEMDDTETGLLHHHHGGG---HHHHHHHaaaaaaalxxaaaaaaa
1g2n_A_3531g2n   A353369SLKMRTLRVDQAEYVALHHHHHHTT--HHHHHHHaaaaaaalpbaaaaaaa
1i7g_A_3521i7g   A362378AMKFNALELDDSDISLFHHHHHTT---HHHHHHHaaaaaaalxbaaaaaaa
1ie9_A_3071ie9   A317333QVGLKKLNLHEEEHVLLHHHHHTT---HHHHHHHaaaaaaalxxaaaaaaa
1iwp_A_4541iwp   A461477VEEMMKRNITGLDIVGAHHHHHHTT--HHHHHHHaaaaaaalxbaaaaaaa
1j77_A_1491j77   A157173VEHLNALNLTPEAEAEAHHHHHHT---HHHHHHHaaaaaaalxxaaaaaaa
1n83_A_3971n83   A407423GKSLCSMHLTEDEIALFHHHHHTT---HHHHHHHaaaaaaalxxaaaaaaa
1nhz_A_6391nhz   A650666SSELHRLQVSYEEYLCMHHHHHHTT--HHHHHHHaaaaaaalxxaaaaaaa
1nq7_A_3361nq7   A346362AKNLCSLQLTEEEIALFHHHHHTT---HHHHHHHaaaaaaalxxaaaaaaa
1nrl_A_3221nrl   A327343HYMLKKLQLHEEEYVLMHHHHHHT---HHHHHHHaaaaaaalxxaaaaaaa
1ojq_A_91ojq   A1733NSLIKSAKYSSKDKMAIHHHHHHH---HHHHHHHaaaaaaalxxaaaaaaa
1osh_A_3661osh   A373389YKSIGELKMTQEEYALLHHHHHTT---HHHHHHHaaaaaaalxxaaaaaaa
1osv_A_3561osv   A366382YKSVGELKMTQEEYALLHHHHHHT---HHHHHHHaaaaaaalxbaaaaaaa
1qkm_A_3721qkm   A384400TSRFRELKLQHKEYLCVHHHHHTT--HHHHHHHHaaaaaaalpxaaaaaaa
1qkn_A_3291qkn   A339355TSRFRELKLQHKEYLCVHHHHHHTT--HHHHHHHaaaaaaavpxaaaaaaa
1qs1_A_701qs1   A7894KEKEKEWKLTATEKGKMHHHHHHH---HHHHHHHaaaaaaavxxaaaaaaa
1rkg_A_3031rkg   A313329QVGLKKLNLHEEEHVLLHHHHHHT---HHHHHHHaaaaaaalxxaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1f20_A_11331f20   A     FADFLAVIN-ADENINE DINUCLEOTIDE W - 1140
1f20_A_11331f20   A     FADFLAVIN-ADENINE DINUCLEOTIDE N - 1143
1i7g_A_3521i7g   A     AZ2(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL} ETHOXY)PHENYL]PROPANOIC ACID I - 354
1i7g_A_3521i7g   A     AZ2(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL} ETHOXY)PHENYL]PROPANOIC ACID M - 355
1i7g_A_3521i7g   A     AZ2(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL} ETHOXY)PHENYL]PROPANOIC ACID K - 358
1i7g_A_3521i7g   A     CPQN,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE S - 373
1i7g_A_3521i7g   A     CPQN,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE L - 377
1ie9_A_3071ie9   A     VDX5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL L - 309
1ie9_A_3071ie9   A     VDX5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL L - 313
1ie9_A_3071ie9   A     VDX5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL Q - 317
1j77_A_1491j77   A     HEMPROTOPORPHYRIN IX CONTAINING FE W - 153
1j77_A_1491j77   A     HEMPROTOPORPHYRIN IX CONTAINING FE A - 180
1j77_A_1491j77   A     HEMPROTOPORPHYRIN IX CONTAINING FE F - 181
1j77_A_1491j77   A     HEMPROTOPORPHYRIN IX CONTAINING FE Y - 184
1n83_A_3971n83   A     CLRCHOLESTEROL F - 399
1n83_A_3971n83   A     CLRCHOLESTEROL I - 400
1n83_A_3971n83   A     CLRCHOLESTEROL V - 403
1n83_A_3971n83   A     CLRCHOLESTEROL F - 404
1nhz_A_6391nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE M - 639
1nhz_A_6391nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE Q - 642
1nhz_A_6391nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE C - 643
1nhz_A_6391nhz   A     HEZHEXANE-1,6-DIOL K - 644
1nhz_A_6391nhz   A     HEZHEXANE-1,6-DIOL H - 645
1nhz_A_6391nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE M - 646
1nhz_A_6391nhz   A     HEZHEXANE-1,6-DIOL M - 646
1nhz_A_6391nhz   A     HEZHEXANE-1,6-DIOL Y - 648
1nhz_A_6391nhz   A     HEZHEXANE-1,6-DIOL K - 667
1nq7_A_3361nq7   A     ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID L - 338
1nq7_A_3361nq7   A     ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID V - 339
1nq7_A_3361nq7   A     ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID A - 342
1nq7_A_3361nq7   A     ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID F - 343
1nrl_A_3221nrl   A     SRL[2-(3,5-DI-TERT-BUTYL-4-HYDROXY-PHENYL)-1-(DIETHOXY-PHOSPHORYL)-VINYL]-PHOSPHONIC ACID DIETHLYL ESTER M - 323
1nrl_A_3221nrl   A     SRL[2-(3,5-DI-TERT-BUTYL-4-HYDROXY-PHENYL)-1-(DIETHOXY-PHOSPHORYL)-VINYL]-PHOSPHONIC ACID DIETHLYL ESTER L - 324
1nrl_A_3221nrl   A     SRL[2-(3,5-DI-TERT-BUTYL-4-HYDROXY-PHENYL)-1-(DIETHOXY-PHOSPHORYL)-VINYL]-PHOSPHONIC ACID DIETHLYL ESTER H - 327
1osh_A_3661osh   A     FEXMETHYL 3-[3-(BENZOYL{[4'-(DIMETHYLAMINO)-1,1'-BIPHENYL -4-YL]METHYL}AMINO)PHENYL]PROPANOATE M - 369
1osh_A_3661osh   A     FEXMETHYL 3-[3-(BENZOYL{[4'-(DIMETHYLAMINO)-1,1'-BIPHENYL -4-YL]METHYL}AMINO)PHENYL]PROPANOATE F - 370
1osh_A_3661osh   A     FEXMETHYL 3-[3-(BENZOYL{[4'-(DIMETHYLAMINO)-1,1'-BIPHENYL -4-YL]METHYL}AMINO)PHENYL]PROPANOATE Y - 373
1osv_A_3561osv   A     CHC6-ETHYL-CHENODEOXYCHOLIC ACID Y - 358
1osv_A_3561osv   A     CHC6-ETHYL-CHENODEOXYCHOLIC ACID I - 359
1osv_A_3561osv   A     CHC6-ETHYL-CHENODEOXYCHOLIC ACID M - 362
1osv_A_3561osv   A     CHC6-ETHYL-CHENODEOXYCHOLIC ACID F - 363
1osv_A_3561osv   A     CHC6-ETHYL-CHENODEOXYCHOLIC ACID Y - 366
1qkm_A_3721qkm   A     GENGENISTEIN I - 373
1qkm_A_3721qkm   A     GENGENISTEIN I - 376
1qkm_A_3721qkm   A     GENGENISTEIN F - 377
1qkm_A_3721qkm   A     GENGENISTEIN L - 380
1qkn_A_3291qkn   A     RALRALOXIFENE I - 331
1qkn_A_3291qkn   A     RALRALOXIFENE F - 332
1qkn_A_3291qkn   A     RALRALOXIFENE L - 335
1qkn_A_3291qkn   A     ACTACETATE ION R - 341
1qkn_A_3291qkn   A     ACTACETATE ION E - 344
1qkn_A_3291qkn   A     ACTACETATE ION L - 345
1rkg_A_3031rkg   A     VD15-{2-[1-(1-METHYL-PROPYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-2-METHYLENE-CYCLOHEXANE-1,3-DIOL L - 305
1rkg_A_3031rkg   A     VD15-{2-[1-(1-METHYL-PROPYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-2-METHYLENE-CYCLOHEXANE-1,3-DIOL L - 309
1rkg_A_3031rkg   A     VD15-{2-[1-(1-METHYL-PROPYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-2-METHYLENE-CYCLOHEXANE-1,3-DIOL Q - 313

Clusters included in this Subclass
CLUSTER: HH.3.108
CLUSTER: HH.4.55
CLUSTER: HH.5.36
CLUSTER: HH.6.67